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This paper studies quantum optimization baselines for the Generalized Traveling Salesman Problem (GTSP), a clustered routing problem that naturally models variant selection and sequencing problems under discrete alternatives. We propose a…

Molecular docking, which aims to find the most stable interacting configuration of a set of molecules, is of critical importance to drug discovery. Although a considerable number of classical algorithms have been developed to carry out…

Biomolecules · Quantitative Biology 2022-10-21 Mohit Pandey , Tristan Zaborniak , Hans Melo , Alexey Galda , Vikram K. Mulligan

The prospect of quantum solutions for complicated optimization problems is contingent on mapping the original problem onto a tractable quantum energy landscape, e.g. an Ising-type Hamiltonian. Subsequently, techniques like adiabatic…

Quantum Physics · Physics 2025-10-17 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

The work explores the integration of quantum computing into logistics and supply chain management, emphasising its potential for use in complex optimisation problems. The discussion introduces quantum computing principles, focusing on…

Quantum Physics · Physics 2025-04-03 Frank Phillipson

We propose a feature-based guidance mechanism to enhance metaheuristic algorithms for solving the Capacitated Vehicle Routing Problem (CVRP). This mechanism leverages an Explainable AI (XAI) model to identify features that correlate with…

Artificial Intelligence · Computer Science 2025-12-23 Bachtiar Herdianto , Romain Billot , Flavien Lucas , Marc Sevaux

Quantum annealing has emerged as a promising approach for solving NP-hard optimization problems, leveraging quantum phenomena such as quantum tunneling to navigate complex energy landscapes. However, the extent to which quantum tunneling…

Quantum Physics · Physics 2026-03-02 Vishwajeet Ohal , Pierre Boulanger

The Vehicle Routing Problem (VRP) is the combinatorial optimization problem of designing routes for vehicles to visit customers in such a fashion that a cost function, typically the number of vehicles, or the total travelled distance is…

Artificial Intelligence · Computer Science 2021-07-01 Sabino Francesco Roselli , Martin Fabian , Knut Åkesson

Modular, distributed and multi-core architectures are currently considered a promising approach for scalability of quantum computing systems. The integration of multiple Quantum Processing Units necessitates classical and quantum-coherent…

Quantum Physics · Physics 2026-04-28 Enrico Russo , Maurizio Palesi , Davide Patti , Giuseppe Ascia , Vincenzo Catania

Solving hard optimization problems is one of the most promising application domains for quantum computers due to the ubiquity of such problems in industry and the availability of broadly applicable quantum speedups. However, the ability of…

Quantum Physics · Physics 2025-07-25 Zichang He , Rudy Raymond , Ruslan Shaydulin , Marco Pistoia

This paper presents a generalization of a method allowing the transformation of the Elliptic Curve Discrete Logarithm Problem (ECDLP) over prime fields to the Quadratic Unconstrained Binary Optimization (QUBO) problem. The original method…

Cryptography and Security · Computer Science 2024-10-14 Łukasz Dzierzkowski

Quantum annealing is a promising paradigm for building practical quantum computers. Compared to other approaches, quantum annealing technology has been scaled up to a larger number of qubits. On the other hand, deep learning has been…

Quantum Physics · Physics 2021-07-07 Michele Sasdelli , Tat-Jun Chin

Node embedding is a key technique for representing graph nodes as vectors while preserving structural and relational properties, which enables machine learning tasks like feature extraction, clustering, and classification. While classical…

Quantum Physics · Physics 2025-03-11 Hristo N. Djidjev

Quantum algorithms for combinatorial optimization typically encode constraints as soft penalties within the objective function, which can reduce efficiency and scalability compared to state-of-the-art classical methods that instead exploit…

Quantum Physics · Physics 2025-11-20 Matteo Vandelli , Francesco Ferrari , Daniele Dragoni

Multi-vehicle routing problem with soft time windows (MVRPSTW) is an indispensable constituent in urban logistics distribution systems. Over the past decade, numerous methods for MVRPSTW have been proposed, but most are based on heuristic…

Artificial Intelligence · Computer Science 2020-10-28 Ke Zhang , Meng Li , Zhengchao Zhang , Xi Lin , Fang He

Developments in cooperative trajectory planning of connected autonomous vehicles (CAVs) have gathered considerable momentum and research attention. Generally, such problems present strong non-linearity and non-convexity, rendering great…

Robotics · Computer Science 2023-01-12 Zhenmin Huang , Shaojie Shen , Jun Ma

Resource allocation of wide-area internet networks is inherently a combinatorial optimization problem that if solved quickly, could provide near real-time adaptive control of internet-protocol traffic ensuring increased network efficacy and…

Quantum Physics · Physics 2024-05-21 Arthur Witt , Jangho Kim , Christopher Körber , Thomas Luu

Quantum annealing has shown significant potential as an approach to near-term quantum computing. Despite promising progress towards obtaining a quantum speedup, quantum annealers are limited by the need to embed problem instances within the…

Data Structures and Algorithms · Computer Science 2018-07-31 Alastair A. Abbott , Cristian S. Calude , Michael J. Dinneen , Richard Hua

The Vehicle Fleet Sizing, Positioning and Routing Problem with Stochastic Customers (VFSPRP-SC) consists on pairing strategic decisions of depot positioning and fleet sizing with operational vehicle routing decisions while taking into…

Optimization and Control · Mathematics 2021-09-21 David Corredor-Montenegro , Maria Jose Consuegra-Laino , Alfaima Lucía Solano-Blanco , Camilo Gómez

Quantum annealing (QA) is proposed for vector perturbation precoding (VPP) in multiple input multiple output (MIMO) communications systems. The mathematical framework of VPP is presented, outlining the problem formulation and the benefits…

Information Theory · Computer Science 2024-02-15 Samuel Winter , Yangyishi Zhang , Gan Zheng , Lajos Hanzo

Electric vehicles (EVs) have been adopted in urban areas to reduce environmental pollution and global warming as a result of the increasing number of freight vehicles. However, there are still deficiencies in routing the trajectories of…

Artificial Intelligence · Computer Science 2022-06-08 Erick Rodríguez-Esparza , Antonio D Masegosa , Diego Oliva , Enrique Onieva
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