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The rate of recombination affects the mode of molecular evolution. In high-recombining sequence, the targets of selection are individual genetic loci; under low recombination, selection collectively acts on large, genetically linked genomic…

Populations and Evolution · Quantitative Biology 2017-11-30 Stephan Schiffels , Ville Mustonen , Michael Lässig

Atherosclerotic plaques are fatty growths in artery walls that cause heart attacks and strokes. Plaque formation is orchestrated by macrophages that are recruited to the artery wall to consume and remove blood-derived lipids, such as…

Cell Behavior · Quantitative Biology 2022-05-12 M. G. Watson , K. L. Chambers , M. R. Myerscough

A novel method for analyzing counterflow diffusion flames, inspired by Zurada's sensitivity approach for neural networks, is proposed to identify critical species influencing the heat release rate in combustion. By further analyzing…

Chemical Physics · Physics 2024-07-03 Liang Ji , Kalyanasundaram Seshadri

Ethanol (CH$_3$CH$_2$OH) is a relatively common molecule, often found in star forming regions. Recent studies suggest that it could be a parent molecule of several so-called interstellar complex organic molecules (iCOMs). Yet, the formation…

This study explored how lifestyle, personal background, and family history contribute to the risk of developing Alcohol Use Disorder (AUD). Survey data from the All of Us Program was utilized to extract information on AUD status, lifestyle,…

Machine Learning · Computer Science 2024-10-25 Chenlan Wang , Gaojian Huang , Yue Luo

In recent studies of methanol masers, a substantial fraction of the objects show maser components aligned in large-scale elliptical configurations. These can be readily interpreted as rings centred on a high mass star in formation, seen in…

Objective: To assess the antioxidant, wound healing, anti-ulcer, and anti-inflammatory properties of Jatropha maheshwari. Methods: Jatropha maheshwari was collected from Kanyakumari district and authenticated. Ethanol was used for…

Quantitative Methods · Quantitative Biology 2024-11-08 Sankar V , Anand Babu K , Deepak M , Poojitha Mallapu , Raghu S , Anandharaj G

Identifying anomalies in the fuel consumption of the vehicles of a fleet is a crucial aspect for optimizing consumption and reduce costs. However, this information alone is insufficient, since fleet operators need to know the causes behind…

Machine Learning · Computer Science 2021-07-23 Alberto Barbado , Óscar Corcho

Mixtures of polyethylene glycol (PEG) and dextran (Dex) represent a widely used class of aqueous two-phase systems (ATPS), with applications ranging from the purification of various biomolecules such as nucleic acids to the synthesis of…

Soft Condensed Matter · Physics 2026-01-28 Hiroki Sakuta , Yuki Akamine , Akari Kamo , Hao Gong , Norikazu Ichihashi , Arash Nikoubashman , Miho Yanagisawa

The reactivity and mechanistic intricacies of azatrienes in Diels-Alder reactions have been relatively unexplored despite their intriguing potential applications. In this study, we employ Molecular Electron Density Theory to theoretically…

Selection bias is pervasive in observational studies. For example, large scale biobanks data can exhibit ``healthy volunteer bias'' when respondents are healthier and of higher socio-economic status than the population they are meant to…

Methodology · Statistics 2026-05-14 Yiwen Qiu , Filip Kovacevic , Shimeng Huang , Peter Spirtes , Francesco Locatello

We report the temperature, pressure and composition dependence of some basic properties of model liquid water-methanol mixtures. For this purpose the isobaric-isothermal molecular dynamics computer simulations are employed. Our principal…

Soft Condensed Matter · Physics 2025-04-01 M. Cruz Sanchez , V. Trejos Montoya , O. Pizio

Methanol (CH$_3$OH) is found to be abundant and widespread towards the Central Molecular Zone, the inner few hundred parsecs of our Galaxy. Its origin is, however, not fully understood. It was proposed that the high cosmic ray ionisation…

Astrophysics of Galaxies · Physics 2017-01-25 Audrey Coutens , Jonathan M. C. Rawlings , Serena Viti , David A. Williams

Cold cores are an early step of star formation, characterized by densities > 10$^4$ cm$^{-3}$, low temperatures (< 15 K), and very low external UV radiation. We investigate the physico-chemical processes at play to tracing the origin of…

Astrophysics of Galaxies · Physics 2023-01-04 A. Taillard , V. WakelaM , P. Gratier , E. Dartois , M. Chabot , J. A. Noble , J. V. Keane , A. C. A. Boogert , D. Harsono

Maternal obesity is associated with increased risk of diabetes, cardiovascular disease and hypertension in adult offspring. Midlife hypercholesterolemia and hypertension are risk factors for Alzheimer's disease, suggesting that the ageing…

Some species of the Baccharis genus have been shown to possess important biomedical properties, including cytotoxic activity. In this study, we examined the cytotoxic effect of methanol extract from Baccharis obtusifolia (Asteraceae) in…

Understanding the pathways through which diet affects human metabolism is a central task in nutritional epidemiology. This article proposes novel methodology to identify food items associated with blood metabolites in two cohorts of…

Coexistence of plants depends on their competition for common resources and indirect interactions mediated by shared exploiters or mutualists. These interactions are driven either by changes in animal abundance (density-mediated…

Populations and Evolution · Quantitative Biology 2019-08-12 Vlastimil Křivan , Tomás A. Revilla

Theories to explain the prevalence of sex and recombination have long been a central theme of evolutionary biology. Yet despite decades of attention dedicated to the evolution of sex and recombination, the widespread pattern of…

Populations and Evolution · Quantitative Biology 2011-12-12 Yaniv Brandvain , Graham Coop