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The lateral diffusion and trapping of neurotransmitter receptors within the postsynaptic membrane of a neuron plays a key role in determining synaptic strength and plasticity. Trapping is mediated by the reversible binding of receptors to…

Quantitative Methods · Quantitative Biology 2022-03-25 Ryan D. Schumm , Paul C. Bressloff

Many important complex networks, including critical infrastructure and emerging industrial automation systems, are becoming increasingly intricate webs of interacting feedback control loops. A fundamental concern is to quantify the control…

Optimization and Control · Mathematics 2017-07-17 Tyler Summers , Justin Ruths

What is the physiological basis of long-term memory? The prevailing view in neuroscience attributes changes in synaptic efficacy to memory acquisition. This view implies that stable memories correspond to stable connectivity patterns.…

Neurons and Cognition · Quantitative Biology 2019-10-09 Lee Susman , Naama Brenner , Omri Barak

In this work, we investigate the use of three information-theoretic quantities -- entropy, mutual information with the class variable, and a class selectivity measure based on Kullback-Leibler divergence -- to understand and study the…

Machine Learning · Computer Science 2022-12-02 Rana Ali Amjad , Kairen Liu , Bernhard C. Geiger

Brain responses related to working memory originate from distinct brain areas and oscillate at different frequencies. EEG signals with high temporal correlation can effectively capture these responses. Therefore, estimating the functional…

Machine Learning · Computer Science 2024-05-01 Harshini Gangapuram , Vidya Manian

An associative memory has been discussed of neural networks consisting of spiking N (=100) Hodgkin-Huxley (HH) neurons with time-delayed couplings, which memorize P patterns in their synaptic weights. In addition to excitatory synapses…

Disordered Systems and Neural Networks · Physics 2009-10-31 Hideo Hasegawa

Various neurophysiological and cognitive functions are based on transferring information between spiking neurons via a complex system of synaptic connections. In particular, the capacity of presynaptic inputs to influence the postsynaptic…

Neurons and Cognition · Quantitative Biology 2018-10-30 Y. Dabaghian

Learning is a complex dynamical process shaped by a range of interconnected decisions. Careful design of hyperparameter schedules for artificial neural networks or efficient allocation of cognitive resources by biological learners can…

Disordered Systems and Neural Networks · Physics 2025-07-11 Francesca Mignacco , Francesco Mori

Learning and memory in the brain are implemented by complex, time-varying changes in neural circuitry. The computational rules according to which synaptic weights change over time are the subject of much research, and are not precisely…

Machine Learning · Statistics 2014-11-18 Scott W. Linderman , Christopher H. Stock , Ryan P. Adams

The background activity of a cortical neural network is modeled by a homogeneous integrate-and-fire network with unreliable inhibitory synapses. Numerical and analytical calculations show that the network relaxes into a stationary state of…

Disordered Systems and Neural Networks · Physics 2007-05-23 Wolfgang Kinzel

The paper analyses and serves with a positioning of various error measures applied in neural network training and identifies that there is no best of measure, although there is a set of measures with changing superiorities in different…

Machine Learning · Computer Science 2022-11-22 Zsolt János Viharos , Ágnes Szűcs

Neural networks with synaptic weights constructed according to the weighted Hebb rule, a variant of the familiar Hebb rule, are studied in the presence of noise(finite temperature), when the number of stored patterns is finite and in the…

Condensed Matter · Physics 2009-10-22 Caren Marzban , Raju Viswanathan

Neuronal dynamics is intrinsically unstable, producing activity fluctuations that are essentially scale-free. Here we show that while these scale-free fluctuations are independent of temporal input statistics, they can be entrained by input…

Neurons and Cognition · Quantitative Biology 2013-05-02 Asaf Gal , Shimon Marom

A fundamental aspect of limitations in learning any computation in neural architectures is characterizing their optimal capacities. An important, widely-used neural architecture is known as autoencoders where the network reconstructs the…

Neurons and Cognition · Quantitative Biology 2017-05-23 Alireza Alemi , Alia Abbara

We propose a new weighted average estimator for the high dimensional parameters under the distributed learning system, in which the weight assigned to each coordinate is precisely proportional to the inverse of the variance of the local…

Methodology · Statistics 2025-02-06 Jun Lu , Xiaoyu Mao , Mengyao Li , Chenping Hou

Modern statistical analysis often encounters high-dimensional problems but with a limited sample size. It poses great challenges to traditional statistical estimation methods. In this work, we adopt auxiliary learning to solve the…

Statistics Theory · Mathematics 2025-01-08 Hanchao Yan , Feifei Wang , Chuanxin Xia , Hansheng Wang

A key question in neuroscience is at which level functional meaning emerges from biophysical phenomena. In most vertebrate systems, precise functions are assigned at the level of neural populations, while single-neurons are deemed…

Neurons and Cognition · Quantitative Biology 2017-03-17 Wieland Brendel , Ralph Bourdoukan , Pietro Vertechi , Christian K. Machens , Sophie Denéve

General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…

Neural and Evolutionary Computing · Computer Science 2016-02-17 David Kappel , Stefan Habenschuss , Robert Legenstein , Wolfgang Maass

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

Neurons and Cognition · Quantitative Biology 2013-04-09 Matthias Schultze-Kraft , Markus Diesmann , Sonja Grün , Moritz Helias

Darwinian evolution tends to produce energy-efficient outcomes. On the other hand, energy limits computation, be it neural and probabilistic or digital and logical. Taking a particular energy-efficient viewpoint, we define neural…

Neurons and Cognition · Quantitative Biology 2021-04-05 William B Levy , Victoria G. Calvert