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The infections and fatalities due to SARS-CoV-2 virus for cases specific to India have been studied using a deterministic susceptible-exposed-infected-recovered-dead (SEIRD) compartmental model. One of the most significant epidemiological…

Populations and Evolution · Quantitative Biology 2020-06-09 Vishwajeet Jha

The real-time analysis of infectious disease surveillance data, e.g., in the form of a time-series of reported cases or fatalities, is essential in obtaining situational awareness about the current dynamics of an adverse health event such…

Methodology · Statistics 2023-01-11 Fanny Bergström , Felix Günther , Michael Höhle , Tom Britton

A key challenge in estimating the infection fatality rate (IFR) -- and its relation with various factors of interest -- is determining the total number of cases. The total number of cases is not known because not everyone is tested, but…

Since two people came down a county of north Seattle with positive COVID-19 (coronavirus-19) in 2019, the current total cases in the United States (U.S.) are over 12 million. Predicting the pandemic trend under effective variables is…

Applications · Statistics 2021-02-10 Qinan Wang , Yaomu Zhou , Xiaofei Chen

Nowcasting and forecasting of epidemic spreading rely on incidence series of reported cases to derive the fundamental epidemiological parameters for a given pathogen. Two relevant drawbacks for predictions are the unknown fractions of…

Populations and Evolution · Quantitative Biology 2022-08-31 Guilherme S. Costa , Wesley Cota , Silvio C. Ferreira

The aim of this study is to propose a modified Susceptible-Exposed-Infectious-Removed (SEIR) model that describes the behaviour of symptomatic, asymptomatic and hospitalized patients of COVID-19 epidemic, including the effect of demographic…

A simple analytical model for modeling the evolution of the 2020 COVID-19 pandemic is presented. The model is based on the numerical solution of the widely used Susceptible-Infectious-Removed (SIR) populations model for describing…

Populations and Evolution · Quantitative Biology 2020-08-26 Efthimios Kaxiras , George Neofotistos , Eleni Angelaki

The advent of the COVID-19 pandemic has instigated unprecedented changes in many countries around the globe, putting a significant burden on the health sectors, affecting the macro economic conditions, and altering social interactions…

Physics and Society · Physics 2020-07-23 Dmitry Gordeev , Philipp Singer , Marios Michailidis , Mathias Müller , SriSatish Ambati

In an effort to provide regional decision support for the public healthcare, we design a data-driven compartment-based model of COVID-19 in Sweden. From national hospital statistics we derive parameter priors, and we develop linear…

Applications · Statistics 2023-07-31 Robin Marin , Håkan Runvik , Alexander Medvedev , Stefan Engblom

We investigate the problem of estimating the distribution of the individual reproduction number governing the COVID-19 pandemic. Under the assumption that this random variable follows a Negative Binomial distribution, we focus on…

Applications · Statistics 2021-01-21 Alexander Braumann , Jonas Krampe , Jens-Peter Kreiss , Efstathios Paparoditis

Having accurate and timely data on confirmed active COVID-19 cases is challenging, since it depends on testing capacity and the availability of an appropriate infrastructure to perform tests and aggregate their results. In this paper, we…

Due to the rapidly evolving COVID-19 pandemic caused by the SARS-CoV-2 virus, quick public health investigations of the relationships between behaviours and infection risk are essential. Recently the test-negative design was proposed to…

Methodology · Statistics 2021-02-09 Mireille E. Schnitzer , Daphna Harel , Vikki Ho , Anita Koushik , Joanna Merckx

Autoregressive (AR) models are useful tools in time series analysis. Inferences under such models are distorted in the presence of measurement error, which is very common in practice. In this article, we establish analytical results for…

Methodology · Statistics 2022-03-11 Qihuang Zhang , Grace Y. Yi

During an epidemic outbreak, decision makers crucially need accurate and robust tools to monitor the pathogen propagation. The effective reproduction number, defined as the expected number of secondary infections stemming from one…

Signal Processing · Electrical Eng. & Systems 2026-01-14 Etienne Lasalle , Barbara Pascal

The COVID-19 pandemic has impacted lives and economies across the globe, leading to many deaths. While vaccination is an important intervention, its roll-out is slow and unequal across the globe. Therefore, extensive testing still remains…

We consider a single outbreak susceptible-infected-recovered (SIR) model and corresponding estimation procedures for the effective reproductive number $\mathcal{R}(t)$. We discuss the estimation of the underlying SIR parameters with a…

Populations and Evolution · Quantitative Biology 2020-04-16 Ariel Cintrón-Arias , Carlos Castillo-Chávez , Luís M. A. Bettencourt , Alun L. Lloyd , H. T. Banks

We propose a compartmental mathematical model for the spread of the COVID-19 disease, showing its usefulness with respect to the pandemic in Portugal, from the first recorded case in the country till the end of the three states of…

Populations and Evolution · Quantitative Biology 2020-11-30 Ana P. Lemos-Paiao , Cristiana J. Silva , Delfim F. M. Torres

In this paper, we present a model to predict the spread of the Covid-19 epidemic and apply it to the specific case of Italy. We started from a simple Susceptible, Infected, Recovered (SIR) model and we added the condition that, after a…

We present a general framework for using existing data to estimate the efficiency gain from using a covariate-adjusted estimator of a marginal treatment effect in a future randomized trial. We describe conditions under which it is possible…

Methodology · Statistics 2021-05-03 Xiudi Li , Sijia Li , Alex Luedtke

An important parameter for COVID-19 is the case fatality rate (CFR). It has been applied to wide applications, including the measure of the severity of the infection, the estimation of the number of infected cases, risk assessment etc.…

Applications · Statistics 2026-02-10 Donghui Yan , Aiyou Chen , Buqing Yang
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