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Related papers: TeaMPI -- Replication-based Resilience without the…

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Replica exchange (REX) is one of the most widely used enhanced sampling methodologies, yet its efficiency is limited by the requirement for a large number of intermediate temperature replicas. Here we present Generative Replica Exchange…

Biomolecules · Quantitative Biology 2026-03-20 Shengjie Huang , Sijie Yang , Jianqiao Yi , Rui Zheng , Haocong Liao , Muzammal Hussain , Yaoquan Tu , Xiaoyun Lu , Yang Zhou

Recent advances in secure hardware technologies, such as Intel SGX or ARM TrustZone, offer an opportunity to substantially reduce the costs of Byzantine fault-tolerance by placing the program code and state within a secure enclave known as…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-24 Sadegh Keshavarzi , Gregory Chockler , Alexey Gotsman

Supercomputers are equipped with an increasingly large number of cores to use computational power as a way of solving problems that are otherwise intractable. Unfortunately, getting serial algorithms to run in parallel to take advantage of…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-12-31 Faisal N. Abu-Khzam , Khuzaima Daudjee , Amer E. Mouawad , Naomi Nishimura

Existing Programming-By-Example (PBE) systems often rely on simplified benchmarks that fail to capture the high structural complexity-such as deeper nesting and frequent Unions-of real-world regexes. To overcome the resulting performance…

Programming Languages · Computer Science 2026-03-27 Seongmin Kim , Hyunjoon Cheon , Su-Hyeon Kim , Yo-Sub Han , Sang-Ki Ko

The orchestration of complex algorithms demands high levels of automation to use modern hardware efficiently. Task-based programming with OpenMP 5.0 is a prominent candidate to accomplish this goal. We study OpenMP 5.0's tasking in the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-11 Holger Schulz , Gonzalo Brito Gadeschi , Oleksandr Rudyy , Tobias Weinzierl

In this work, we describe a self-replication-based mechanism for designing agents of increasing complexity. We demonstrate the validity of this approach by solving simple, standard evolutionary computation problems in simulation. In the…

Neural and Evolutionary Computing · Computer Science 2018-07-20 Thommen George Karimpanal

With the proliferation of Trusted Execution Environments (TEEs) such as Intel SGX, a number of cloud providers will soon introduce TEE capabilities within their offering (e.g., Microsoft Azure). Although the integration of SGX within the…

Cryptography and Security · Computer Science 2018-09-14 Claudio Soriente , Ghassan Karame , Wenting Li , Sergey Fedorov

Exascale computing will get mankind closer to solving important social, scientific and engineering problems. Due to high prototyping costs, High Performance Computing (HPC) system architects make use of simulation models for design space…

Performance · Computer Science 2018-03-28 Alexandra Ferreron , Radhika Jagtap , Sascha Bischoff , Roxana Rusitoru

We investigate the merits of replication, and provide methods for optimal design (including replicates), with the goal of obtaining globally accurate emulation of noisy computer simulation experiments. We first show that replication can be…

Methodology · Statistics 2019-01-28 Mickael Binois , Jiangeng Huang , Robert B Gramacy , Mike Ludkovski

Machine learning workflow development is a process of trial-and-error: developers iterate on workflows by testing out small modifications until the desired accuracy is achieved. Unfortunately, existing machine learning systems focus…

Databases · Computer Science 2018-12-17 Doris Xin , Stephen Macke , Litian Ma , Jialin Liu , Shuchen Song , Aditya Parameswaran

It is commonly agreed that highly parallel software on Exascale computers will suffer from many more runtime failures due to the decreasing trend in the mean time to failures (MTTF). Therefore, it is not surprising that a lot of research is…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-05-19 Faisal Shahzad , Moritz Kreutzer , Thomas Zeiser , Rui Machado , Andreas Pieper , Georg Hager , Gerhard Wellein

Models invoking the chemical master equation are used in many areas of science, and, hence, their simulation is of interest to many researchers. The complexity of the problems at hand often requires considerable computational power, so a…

Biological Physics · Physics 2016-03-02 Fabian Spill , Philip K. Maini , Helen Byrne

The rapid advancement of large language models (LLMs) has spurred significant interest in tool learning, where LLMs are augmented with external tools to tackle complex tasks. However, existing tool environments face challenges in balancing…

Computation and Language · Computer Science 2025-03-27 Zhicheng Guo , Sijie Cheng , Yuchen Niu , Hao Wang , Sicheng Zhou , Wenbing Huang , Yang Liu

Reproducibility of modeling is a problem that exists for any machine learning practitioner, whether in industry or academia. The consequences of an irreproducible model can include significant financial costs, lost time, and even loss of…

Machine Learning · Computer Science 2018-10-11 Peter Sugimura , Florian Hartl

As transformer sequence lengths grow, existing pipeline parallelisms incur suboptimal performance due to the quadratic attention computation and the substantial memory overhead. To relieve these challenges, we propose HelixPipe, a novel…

Machine Learning · Computer Science 2025-07-02 Geng Zhang , Shenggan Cheng , Xuanlei Zhao , Ziming Liu , Yang You

In this paper, we propose a pragmatic approach to improve reproducibility of experimental analyses of traffic engineering (TE) algorithms, whose implementation, evaluation and comparison are currently hard to replicate. Our envisioned goal…

Networking and Internet Architecture · Computer Science 2017-10-25 Steven Gay , Pierre Schaus , Stefano Vissicchio

Recent advances in probabilistic modelling have led to a large number of simulation-based inference algorithms which do not require numerical evaluation of likelihoods. However, a public benchmark with appropriate performance metrics for…

Machine Learning · Statistics 2021-04-12 Jan-Matthis Lueckmann , Jan Boelts , David S. Greenberg , Pedro J. Gonçalves , Jakob H. Macke

The availability of large idea repositories (e.g., the U.S. patent database) could significantly accelerate innovation and discovery by providing people with inspiration from solutions to analogous problems. However, finding useful…

Computation and Language · Computer Science 2017-06-20 Tom Hope , Joel Chan , Aniket Kittur , Dafna Shahaf

The ability to record and replay program executions with low overhead enables many applications, such as reverse-execution debugging, debugging of hard-to-reproduce test failures, and "black box" forensic analysis of failures in deployed…

Programming Languages · Computer Science 2017-05-18 Robert O'Callahan , Chris Jones , Nathan Froyd , Kyle Huey , Albert Noll , Nimrod Partush

Scientific knowledge discovery increasingly relies on large language models, yet many existing scholarly assistants depend on proprietary systems with tens or hundreds of billions of parameters. Such reliance limits reproducibility and…

Information Retrieval · Computer Science 2026-04-23 Florian Kelber , Matthias Jobst , Yuni Susanti , Michael Färber