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The ordering of rod-like particles in soft, deformable containers emerges from the interplay of anisotropic interactions, geometric confinement, and boundary compliance. This competition couples internal particle organization to container…

Soft Condensed Matter · Physics 2026-05-22 Stijn van der Ham , André F. V. Matias , Marjolein Dijkstra , Hanumantha Rao Vutukuri

The actin cytoskeleton is a key component in the machinery of eukaryotic cells, and it selfassembles out of equilibrium into a wide variety of biologically crucial structures. While the molecular mechanisms involved are well characterized,…

Soft Condensed Matter · Physics 2017-01-04 Giulia Foffano , Nicolas Levernier , Martin Lenz

Controlling the motion of active matter is a central issue that has recently garnered significant attention in fields ranging from non-equilibrium physics to chemical engineering and biology. Distinct methods for controlling active matter…

Soft Condensed Matter · Physics 2023-07-25 Archit Negi , Kazusa Beppu , Yusuke T. Maeda

Active matter systems evade the constraints of thermal equilibrium, leading to the emergence of intriguing collective behavior. A paradigmatic example is given by motor-filament mixtures, where the motion of motor proteins drives alignment…

Soft Condensed Matter · Physics 2024-09-11 Filippo De Luca , Ivan Maryshev , Erwin Frey

We model analytically the dynamics of a cytoskeletal filament in a motility assay. The filament is described as rigid rod free to slide in two dimensions. The motor proteins consist of polymeric tails tethered to the plane and modeled as…

Statistical Mechanics · Physics 2015-03-19 Shiladitya Banerjee , M. Cristina Marchetti , Kristian Müller-Nedebock

We use Brownian dynamics simulations and theory to study the over-damped spatiotemporal dynamics and pattern formation in a fluid-permeated array of equally spaced, active, elastic filaments that are pinned at one end and free at the other.…

Soft Condensed Matter · Physics 2024-12-31 Sonu Karayat , Prashant K. Purohit , L. Mahadevan , Arvind Gopinath , Raghunath Chelakkot

We characterize cell motion in experiments and show that the transition to collective motion in colonies of gliding bacterial cells confined to a monolayer appears through the organization of cells into larger moving clusters. Collective…

Cytoskeletal motor proteins are involved in major intracellular transport processes which are vital for maintaining appropriate cellular function. The motor exhibits distinct states of motility: active motion along filaments, and…

Biological Physics · Physics 2016-11-29 Anne E. Hafner , Ludger Santen , Heiko Rieger , M. Reza Shaebani

Anisotropic colloidal particles have the ability to self-assemble into cholesteric structures. We used molecular dynamics to simulate the self-assembly of ellipsoidal particles with the objective to establish a general framework to reveal…

Soft Condensed Matter · Physics 2024-01-08 Jiaxin Hou , William Sampson , Ahu Gümrah Dumanli

Active hydrodynamic theories are a powerful tool to study the emergent ordered phases of internally driven particles such as bird flocks, bacterial suspension and their artificial analogues. While theories of orientationally ordered phases…

Soft Condensed Matter · Physics 2019-03-06 Ananyo Maitra , Martin Lenz

Motility coupled to responsive behavior is essential for many microorganisms to seek and establish appropriate habitats. One of the simplest possible responses, reversing the direction of motion, is believed to enable filamentous…

The occurrence of coiled or helical morphologies is common in nature, from plant roots to DNA packaging into viral capsids, as well as in applications such as oil drilling processes. In many examples, chiral structures result from the…

Cytoskeletal networks, which are essentially motor-filament assemblies, play a major role in many developmental processes involving structural remodeling and shape changes. These are achieved by nonequilibrium self-organization processes…

Soft Condensed Matter · Physics 2014-12-22 Shenshen Wang , Peter G. Wolynes

Non-equilibrium processes which convert chemical energy into mechanical motion enable the motility of organisms. Bundles of inextensible filaments driven by energy transduction of molecular motors form essential components of micron-scale…

Soft Condensed Matter · Physics 2013-06-13 Abhrajit Laskar , Rajeev Singh , Somdeb Ghose , Gayathri Jayaraman , P. B. Sunil Kumar , R. Adhikari

Molecular-motor generated active stresses drive the cytoskeleton away from equilibrium, endowing it with tunable mechanical properties that are essential for diverse functions such as cell division and motility[1-5]. Designing analogous…

Left-right axis specification establishes embryonic laterality through asymmetric signaling cascades originating at the cellular scale. We previously reported the presence of a directionality bias in confined pairs of endothelial (and…

Cell Behavior · Quantitative Biology 2026-03-31 Egun Im , Ghina Badih , Laetitia Kurzawa , Andreas Buttenschön , Calina Copos

Myosin motor proteins drive vigorous steady-state fluctuations in the actin cytoskeleton of cells. Endogenous embedded semiflexible filaments such as microtubules, or added filaments such as single-walled carbon nanotubes are used as novel…

Biological Physics · Physics 2016-06-21 J. Gladrow , N. Fakhri , F. C. MacKintosh , C. F. Schmidt , C. P. Broedersz

Synchronous and directed ciliary beating in trachea allows transport and ejection of virus and dust from the body. This ciliary function depends on the coordinated configuration of basal bodies (root of cilia) in apical cell membrane.…

Cell Behavior · Quantitative Biology 2020-03-19 Toshinori Namba , Shuji Ishihara

The colonisation of a soft passive material by motile cells such as bacteria is common in biology. The resulting colonies of the invading cells are often observed to exhibit intricate patterns whose morphology and dynamics can depend on a…

Soft Condensed Matter · Physics 2021-01-12 Mohammad Imaran , Mandar Inamdar , Ranganathan Prabhakar , Raghunath Chelakkot

Cytoskeletal motors known as motor proteins are molecules that drive cellular transport along several parallel cytoskeletal filaments and support many biological processes. Experimental evidences suggest that they interact with the nearest…

Statistical Mechanics · Physics 2017-11-22 Tripti Midha , A. K. Gupta