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Related papers: Repurpose Open Data to Discover Therapeutics for C…

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Drug repurposing (or repositioning) is the process of finding new therapeutic uses for drugs already approved by drug regulatory authorities (e.g., the Food and Drug Administration (FDA) and Therapeutic Goods Administration (TGA)) for other…

Artificial Intelligence · Computer Science 2023-06-27 Chaarvi Bansal , Rohitash Chandra , Vinti Agarwal , P. R. Deepa

The coronavirus disease (COVID-19) has claimed the lives of over 350,000 people and infected more than 6 million people worldwide. Several search engines have surfaced to provide researchers with additional tools to find and retrieve…

Novel coronavirus (COVID-19) outbreak, has raised a calamitous situation all over the world and has become one of the most acute and severe ailments in the past hundred years. The prevalence rate of COVID-19 is rapidly rising every day…

Image and Video Processing · Electrical Eng. & Systems 2022-09-09 Md. Milon Islam , Fakhri Karray , Reda Alhajj , Jia Zeng

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the strain of coronavirus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic. Currently there is no known vaccine or…

Biomolecules · Quantitative Biology 2020-06-29 Emilio Angelina , Sebastian Andujar , Oscar Parravicini , Daniel Enriz , Nelida Peruchena

The COVID-19 (coronavirus) is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was first identified in mid-December 2019 in the Hubei province of Wuhan, China and by now has spread…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Aditya Saxena , Shamsheer Pal Singh

COVID-19, the disease caused by the SARS-CoV-2 virus, has been declared a pandemic by the World Health Organization, which has reported over 18 million confirmed cases as of August 5, 2020. In this review, we present an overview of recent…

Computers and Society · Computer Science 2021-01-12 Joseph Bullock , Alexandra Luccioni , Katherine Hoffmann Pham , Cynthia Sin Nga Lam , Miguel Luengo-Oroz

Drug repurposing is an unconventional approach that is used to investigate new therapeutic aids of existing and shelved drugs. Recent advancement in technologies and the availability of the data of genomics, proteomics, transcriptomics,…

Quantitative Methods · Quantitative Biology 2022-07-27 Imra Aqeel , Abdul Majid , Muhammad Ismail , Hina Bashir

The outbreak of novel coronavirus disease (COVID- 19) has claimed millions of lives and has affected all aspects of human life. This paper focuses on the application of deep learning (DL) models to medical imaging and drug discovery for…

Image and Video Processing · Electrical Eng. & Systems 2021-07-21 Subrato Bharati , Prajoy Podder , M. Rubaiyat Hossain Mondal , V. B. Surya Prasath

To better understand the potential of drug repurposing in COVID-19, we analyzed control strategies over essential host factors for SARS-CoV-2 infection. We constructed comprehensive directed protein-protein interaction networks integrating…

The 2019 coronavirus disease (COVID-19) became a worldwide pandemic with currently no effective antiviral drug except treatments for symptomatic therapy. Flux balance analysis is an efficient method to analyze metabolic networks. It allows…

Molecular Networks · Quantitative Biology 2021-11-12 Ali Kishk , Maria Pires Pacheco , Thomas Sauter

The outbreak of COVID-19 disease caused more than 100,000 deaths so far in the USA alone. It is necessary to conduct an initial screening of patients with the symptoms of COVID-19 disease to control the spread of the disease. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Md Manjurul Ahsan , Kishor Datta Gupta , Mohammad Maminur Islam , Sajib Sen , Md. Lutfar Rahman , Mohammad Shakhawat Hossain

After emerging in China in late 2019, the novel Severe acute respiratory syndrome-like coronavirus 2 (SARS-CoV-2) spread worldwide and as of early 2021, continues to significantly impact most countries. Only a small number of coronaviruses…

SARS-CoV2, which causes coronavirus disease (COVID-19) is continuing to spread globally and has become a pandemic. People have lost their lives due to the virus and the lack of counter measures in place. Given the increasing caseload and…

The novel coronavirus disease, named COVID-19, emerged in China in December 2019, and has rapidly spread around the world. It is clearly urgent to fight COVID-19 at global scale. The development of methods for identifying drug uses based on…

Quantitative Methods · Quantitative Biology 2021-10-06 Lu Han , G. C. Shan , B. F. Chu , H. Y. Wang , Z. J. Wang , S. Q. Gao , W. X. Zhou

The recent global pandemic of Coronavirus Disease 2019 (COVID-19) caused by the new coronavirus SARS-CoV-2 presents an urgent need for new therapeutic candidates. Many efforts have been devoted to screening existing drug libraries with the…

Quantitative Methods · Quantitative Biology 2020-07-27 Hu Zhu , Catherine Z. Chen , Srilatha Sakamuru , Anton Simeonov , Mathew D. Hall , Menghang Xia , Wei Zheng , Ruili Huang

The emergence of the novel COVID-19 pandemic has had a significant impact on global healthcare and the economy over the past few months. The virus's rapid widespread has led to a proliferation in biomedical research addressing the pandemic…

Artificial Intelligence · Computer Science 2020-07-21 Chongyan Chen , Islam Akef Ebeid , Yi Bu , Ying Ding

The world has faced the devastating outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), or COVID-19, in 2020. Research in the subject matter was fast-tracked to such a point that scientists were struggling to keep up…

Information Retrieval · Computer Science 2020-09-03 Maksim Ekin Eren , Nick Solovyev , Edward Raff , Charles Nicholas , Ben Johnson

Novel Coronavirus (COVID-19) has drastically overwhelmed more than 200 countries affecting millions and claiming almost 1 million lives, since its emergence in late 2019. This highly contagious disease can easily spread, and if not…

Coronavirus disease (COVID-19) is an infectious disease discovered in 2019 and currently in outbreak across the world. Lung injury with severe respiratory failure is the leading cause of death in COVID-19, brought by severe acute…

Tissues and Organs · Quantitative Biology 2020-05-05 Bing He , Lana Garmire

Knowledge graph (KG) is used to represent data in terms of entities and structural relations between the entities. This representation can be used to solve complex problems such as recommendation systems and question answering. In this…

Artificial Intelligence · Computer Science 2022-12-09 Ajay Kumar Gogineni