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The screening testing is an effective tool to control the early spread of an infectious disease such as COVID-19. When the total testing capacity is limited, we aim to optimally allocate testing resources among n counties. We build a…

Methodology · Statistics 2022-03-28 Yaxuan Huang , Zheng Tracy Ke , Jiashun Jin

The relative case fatality rates (CFRs) between groups and countries are key measures of relative risk that guide policy decisions regarding scarce medical resource allocation during the ongoing COVID-19 pandemic. In the middle of an active…

Quantitative Methods · Quantitative Biology 2022-12-08 Anastasios Nikolas Angelopoulos , Reese Pathak , Rohit Varma , Michael I. Jordan

The COVID-19 pandemic has caused major disturbance to human life. An important reason behind the widespread social anxiety is the huge uncertainty about the pandemic. A fundamental uncertainty is how many or what percentage of people have…

Populations and Evolution · Quantitative Biology 2021-03-04 Donghui Yan , Ying Xu , Pei Wang

The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…

Machine Learning · Computer Science 2020-07-28 Rahul Singh , Fang Liu , Ness B. Shroff

Globally the SARS-CoV-2 coronavirus has infected more than 59 million people and killed more than 1.39 million. Designing and monitoring interventions to slow and stop the spread of the virus require knowledge of how many people have been…

Policy responses to COVID-19, particularly those related to non-pharmaceutical interventions, are unprecedented in scale and scope. Epidemiologists are more involved in policy decisions and evidence generation than ever before. However,…

Methodology · Statistics 2021-04-20 Noah A Haber , Emma Clarke-Deelder , Joshua A Salomon , Avi Feller , Elizabeth A Stuart

Due to delay in reporting, the daily national and statewide COVID-19 incidence counts are often unreliable and need to be estimated from recent data. This process is known in economics as nowcasting. We describe in this paper a simple…

Quantitative Methods · Quantitative Biology 2021-04-07 Saumya Yashmohini Sahai , Saket Gurukar , Wasiur R. KhudaBukhsh , Srinivasan Parthasarathy , Grzegorz A. Rempala

The coronavirus disease 2019 (COVID-19) has quickly grown from a regional outbreak in Wuhan, China to a global pandemic. Early estimates of the epidemic growth and incubation period of COVID-19 may have been biased due to sample selection.…

Applications · Statistics 2020-09-25 Qingyuan Zhao , Nianqiao Ju , Sergio Bacallado , Rajen D. Shah

At the time of this article, COVID-19 has been transmitted to more than 42 million people and resulted in more than 673,000 deaths across the United States. Throughout this pandemic, public health authorities have monitored the results of…

Computers and Society · Computer Science 2021-10-19 Zhen Zhong , Ribhu Sengupta , Kamran Paynabar , Lance A. Waller

Timely prediction of the COVID-19 progression is not possible without a comprehensive understanding of environmental factors that may affect the infection transmissibility. Studies addressing parameters that may influence COVID-19…

Populations and Evolution · Quantitative Biology 2021-03-30 Igor Salom , Andjela Rodic , Ognjen Milicevic , Dusan Zigic , Magdalena Djordjevic , Marko Djordjevic

Over the past few months, the outbreak of Coronavirus disease (COVID-19) has been expanding over the world. A reliable and accurate dataset of the cases is vital for scientists to conduct related research and for policy-makers to make…

Applications · Statistics 2020-12-01 Guannan Wang , Zhiling Gu , Xinyi Li , Shan Yu , Myungjin Kim , Yueying Wang , Lei Gao , Li Wang

Propensity score methods are an important tool to help reduce confounding in non-experimental studies. Most propensity score methods assume that covariates are measured without error. However, covariates are often measured with error, which…

Methodology · Statistics 2017-06-08 Hwanhee Hong , David A. Aaby , Juned Siddique , Elizabeth A. Stuart

We present a method for efficient estimation of the prevalence of infection in a population with high accuracy using only a small number of tests. The presented approach uses pool testing with a mix of pool sizes of various sizes. The test…

Applications · Statistics 2020-04-08 Itsik Bergel

To strengthen inferences meta analyses are commonly used to summarize information from a set of independent studies. In some cases, though, the data may not satisfy the assumptions underlying the meta analysis. Using three Bayesian methods…

Applications · Statistics 2022-04-07 Dexter Cahoy , Joseph Sedransk

The spread of COVID-19 has been greatly impacted by regulatory policies and behavior patterns that vary across counties, states, and countries. Population-level dynamics of COVID-19 can generally be described using a set of ordinary…

Applications · Statistics 2022-04-11 Joshua P. Keller , Tianjian Zhou , Andee Kaplan , G. Brooke Anderson , Wen Zhou

We consider the problem of estimating the reproduction number $R_t$ of an epidemic for populations where the probability of detection of cases depends on a known covariate. We argue that in such cases the normal empirical estimator can fail…

Applications · Statistics 2020-12-04 Guido Sanguinetti

A number of models in mathematical epidemiology have been developed to account for control measures such as vaccination or quarantine. However, COVID-19 has brought unprecedented social distancing measures, with a challenge on how to…

Populations and Evolution · Quantitative Biology 2021-09-07 Magdalena Djordjevic , Andjela Rodic , Igor Salom , Dusan Zigic , Ognjen Milicevic , Bojana Ilic , Marko Djordjevic

In the absence of neither an effective treatment or vaccine and with an incomplete understanding of the epidemiological cycle, Govt. has implemented a nationwide lockdown to reduce COVID-19 transmission in India. To study the effect of…

Populations and Evolution · Quantitative Biology 2020-08-26 Tridip Sardar , Sk Shahid Nadim , Sourav Rana , Joydev Chattopadhyay

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

Populations and Evolution · Quantitative Biology 2021-01-27 Timo de Wolff , Dirk Pflüger , Michael Rehme , Janin Heuer , Martin-Immanuel Bittner

During an ongoing epidemic, especially in the case of a new agent, data are partial and sparse, also affected by external factors as for example climatic effects or preparedness and response capability of healthcare structures. Despite that…

Methodology · Statistics 2021-04-26 Filippo Carone Fabiani