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Related papers: Repositioning of 8565 existing drugs for COVID-19

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The new coronavirus (2019-nCoV or SARS-CoV2), inducing the current pandemic disease (COVID-19) and causing pneumoniae in humans, is dramatically increasing in epidemic scale since its first appearance in Wuhan, China, in December 2019. The…

Molecular Networks · Quantitative Biology 2020-03-28 Maria Luisa Chiusano

Development of new drugs is an expensive and time-consuming process. Due to the world-wide SARS-CoV-2 outbreak, it is essential that new drugs for SARS-CoV-2 are developed as soon as possible. Drug repurposing techniques can reduce the time…

Machine Learning · Computer Science 2022-01-19 Shrimon Mukherjee , Madhusudan Ghosh , Partha Basuchowdhuri

The novel coronavirus disease, named COVID-19, emerged in China in December 2019, and has rapidly spread around the world. It is clearly urgent to fight COVID-19 at global scale. The development of methods for identifying drug uses based on…

Quantitative Methods · Quantitative Biology 2021-10-06 Lu Han , G. C. Shan , B. F. Chu , H. Y. Wang , Z. J. Wang , S. Q. Gao , W. X. Zhou

Diabetes is considered as an critical comorbidity linked with the latest coronavirus disease 2019 (COVID-19) which spreads through Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2). The diabetic patients have higher threat of…

Other Quantitative Biology · Quantitative Biology 2022-04-07 Amit M. Joshi , Urvashi P. Shukla , Saraju P. Mohanty

The novel coronavirus, SARS-CoV-2, and the disease it causes, COVID-19 was declared a pandemic on March 11, 2020 by the World Health Organization. Since then, the disease has spread all over the world, with the United States becoming the…

Populations and Evolution · Quantitative Biology 2020-04-08 Keshav Amla , Tarun Amla

Globally the SARS-CoV-2 coronavirus has infected more than 59 million people and killed more than 1.39 million. Designing and monitoring interventions to slow and stop the spread of the virus require knowledge of how many people have been…

The outbreak of COVID-19 caused by SARS-CoV-2 has rapidly spread worldwide and has caused over 1,400,000 infections and 80,000 deaths. There are currently no drugs or vaccines with proven efficacy for its prevention and little knowledge was…

Genomics · Quantitative Biology 2020-04-13 Zhi Liu , Jianwei Wang , Yuyu Xu , Mengchen Guo , Kai Mi , Rui Xu , Yang Pei , Qiangkun Zhang , Xiaoting Luan , Zhibin Hu , Xingyin Liu#

The pandemic of COVID-19 has caused millions of infections, which has led to a great loss all over the world, socially and economically. Due to the false-negative rate and the time-consuming of the conventional Reverse Transcription…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Delong Chen , Shunhui Ji , Fan Liu , Zewen Li , Xinyu Zhou

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a variable clinical presentation that ranges from asymptomatic, to severe disease with cytokine storm. The mortality rates also differ across the globe, ranging from 0.5-13%.…

As a reaction to the pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a multitude of clinical trials for the treatment of SARS-CoV-2 or the resulting corona disease (COVID-19) are globally at various stages from…

Applications · Statistics 2020-12-04 Jan Beyersmann , Tim Friede , Claudia Schmoor

Covid-19 infection, which spread to the whole world in December 2019 and is still active, caused more than 250 thousand deaths in the world today. Researches on this subject have been focused on analyzing the genetic structure of the virus,…

Machine Learning · Computer Science 2023-04-25 Selcuk Yazar

More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies,…

Background: The COVID-19 pandemic clock is ticking and the survival of many of mankind's modern institutions and or survival of many individuals is at stake. There is a need for treatments to significantly reduce the morbidity and mortality…

Genomics · Quantitative Biology 2020-12-08 Ali Ebrahimpour Boroojeny , Hamidreza Chitsaz

The world is still struggling in controlling and containing the spread of the COVID-19 pandemic caused by the SARS-CoV-2 virus. The medical conditions associated with SARS-CoV-2 infections have resulted in a surge in the number of patients…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Hossein Aboutalebi , Maya Pavlova , Mohammad Javad Shafiee , Ali Sabri , Amer Alaref , Alexander Wong

Coronavirus disease 2019 (CoViD-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Among many symptoms, cough, fever and tiredness are the most common. People over 60 years old and with…

Dynamical Systems · Mathematics 2021-08-25 João P. S. Maurício de Carvalho , Beatriz Moreira-Pinto

The COVID-19 pandemic caused by the SARS-CoV-2 virus has spread rapidly worldwide, leading to a global outbreak. Most governments, enterprises, and scientific research institutions are participating in the COVID-19 struggle to curb the…

Quantitative Methods · Quantitative Biology 2021-03-12 Jianguo Chen , Kenli Li , Zhaolei Zhang , Keqin Li , Philip S. Yu

The development of therapeutic targets for COVID-19 treatment is based on the understanding of the molecular mechanism of pathogenesis. The identification of genes and proteins involved in the infection mechanism is the key to shed out…

Biomolecules · Quantitative Biology 2021-05-19 Jayanta Kumar Das , Swarup Roy , Pietro Hiram Guzzi

The Coronavirus Disease (COVID-19) pandemic caused by the SARS-coronavirus 2 (SARS-CoV-2) urgently calls for the design of drugs directed against this new virus. Given its essential role in proteolytic processing, the main protease Mpro has…

Biomolecules · Quantitative Biology 2020-05-21 Cintia A. Menendez , Fabian Bylehn , Gustavo R. Perez-Lemus , Walter Alvarado , Juan J. de Pablo

Recent epidemiological data report that worldwide more than 53 million people have been infected by SARS-CoV-2, resulting in 1.3 million deaths. The disease has been spreading very rapidly and few months after the identification of the…