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Inferring causality using longitudinal observational databases is challenging due to the passive way the data are collected. The majority of associations found within longitudinal observational data are often non-causal and occur due to…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Jenna Reps , Uwe Aickelin

Stress detection and classification from wearable sensor data is an emerging area of research with significant implications for individuals' physical and mental health. In this work, we introduce a new dataset, ADARP, which contains…

Human-Computer Interaction · Computer Science 2022-06-30 Ramesh Kumar Sah , Michael McDonell , Patricia Pendry , Sara Parent , Hassan Ghasemzadeh , Michael J Cleveland

Difficult-to-treat depression (DTD) has been proposed as a broader and more clinically comprehensive perspective on a person's depressive disorder where despite treatment, they continue to experience significant burden. We sought to develop…

Computation and Language · Computer Science 2024-02-13 Isabelle Lorge , Dan W. Joyce , Niall Taylor , Alejo Nevado-Holgado , Andrea Cipriani , Andrey Kormilitzin

Personalized medicine seeks to identify the causal effect of treatment for a particular patient as opposed to a clinical population at large. Most investigators estimate such personalized treatment effects by regressing the outcome of a…

Machine Learning · Statistics 2021-09-02 Eric V. Strobl , Shyam Visweswaran

Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of…

Information Retrieval · Computer Science 2017-09-07 Shashank Gupta , Sachin Pawar , Nitin Ramrakhiyani , Girish Palshikar , Vasudeva Varma

Clinical interactions are initially recorded and documented in free text medical notes. ICD coding is the task of classifying and coding all diagnoses, symptoms and procedures associated with a patient's visit. The process is often manual…

Information Retrieval · Computer Science 2020-06-09 Zachariah Zhang , Jingshu Liu , Narges Razavian

Big data has found applications in multiple domains. One of the largest sources of textual big data is scientific documents and papers. Big scholarly data have been used in numerous ways to create innovative applications such as…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-19 Samiya Khan , Xiufeng Liu , Mansaf Alam

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

Computational Engineering, Finance, and Science · Computer Science 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

Unstructured text from legal, medical, and administrative sources offers a rich but underutilized resource for research in public health and the social sciences. However, large-scale analysis is hampered by two key challenges: the presence…

Computation and Language · Computer Science 2025-07-16 Anders Ledberg , Anna Thalén

We explore the hyperparameters and introduce a methodological framework to convert disease patterns from time series data of blood test results into correlation graphs for causal hypothesis exploration. The networks represent hypotheses…

Other Quantitative Biology · Quantitative Biology 2025-12-29 David Patrick Duys Montealegre , Alexander Fulton , Mahta Haghighat Ghahfarokhi , Abicumaran Uthamacumaran , Hector Zenil

Objective: Electronic health records (EHR) are widely available to complement administrative data-based disease surveillance and healthcare performance evaluation. Defining conditions from EHR is labour-intensive and requires extensive…

Computation and Language · Computer Science 2025-04-09 Jie Pan , Seungwon Lee , Cheligeer Cheligeer , Elliot A. Martin , Kiarash Riazi , Hude Quan , Na Li

This paper explores whether the use of drug reviews and social media could be leveraged as potential alternative sources for pharmacovigilance of adverse drug reactions (ADRs). We examined the performance of BERT alongside two variants that…

Computation and Language · Computer Science 2020-04-21 Brent Biseda , Katie Mo

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Machine Learning · Computer Science 2020-05-01 Chirag Nagpal , Dennis Wei , Bhanukiran Vinzamuri , Monica Shekhar , Sara E. Berger , Subhro Das , Kush R. Varshney

With the explosive increase of big data in industry and academic fields, it is necessary to apply large-scale data processing systems to analysis Big Data. Arguably, Spark is state of the art in large-scale data computing systems nowadays,…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-17 Shanjiang Tang , Bingsheng He , Ce Yu , Yusen Li , Kun Li

There has been a rapidly growing interest in Automatic Symptom Detection (ASD) and Automatic Diagnosis (AD) systems in the machine learning research literature, aiming to assist doctors in telemedicine services. These systems are designed…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Zhi Wen , Julien Martel , Joumana Ghosn

Treatment planning for chronic diseases is a critical task in medical artificial intelligence, particularly in traditional Chinese medicine (TCM). However, generating optimized sequential treatment strategies for patients with chronic…

Artificial Intelligence · Computer Science 2023-04-26 Kuo Yang , Zecong Yu , Xin Su , Xiong He , Ning Wang , Qiguang Zheng , Feidie Yu , Zhuang Liu , Tiancai Wen , Xuezhong Zhou

Chronic pain is a significant global health issue, with many patients experiencing persistent pain despite no identifiable organic cause, classified as nociplastic pain. Increasing evidence highlights the role of danger signal processing in…

Neurons and Cognition · Quantitative Biology 2025-02-18 Carmit Himmelblau Gat , Natalia Polyviannaya , Pavel Goldstein

Medication recommendation is a crucial task for intelligent healthcare systems. Previous studies mainly recommend medications with electronic health records (EHRs). However, some details of interactions between doctors and patients may be…

Computation and Language · Computer Science 2022-09-16 Zhenfeng He , Yuqiang Han , Zhenqiu Ouyang , Wei Gao , Hongxu Chen , Guandong Xu , Jian Wu

In modern drug development, the broader availability of high-dimensional observational data provides opportunities for scientist to explore subgroup heterogeneity, especially when randomized clinical trials are unavailable due to cost and…

Methodology · Statistics 2021-02-24 Xinzhou Guo , Linqing Wei , Chong Wu , Jingshen Wang
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