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X-ray photon-counting computed tomography (PCCT) for extremity allows multi-energy high-resolution (HR) imaging but its radiation dose can be further improved. Despite the great potential of deep learning techniques, their application in HR…

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Multiple objective assessment of image-quality-based studies have reported that several deep-learning-based denoising methods show limited performance on signal-detection tasks. Our goal was to investigate the reasons for this limited…

The cost-effectiveness and practical harmlessness of ultrasound imaging have made it one of the most widespread tools for medical diagnosis. Unfortunately, the beam-forming based image formation produces granular speckle noise, blurring,…

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image contrast in multispectral optoacoustic tomography (MSOT) can be severely reduced by electrical noise and interference in the acquired optoacoustic signals. Signal processing techniques have proven insufficient to remove the effects of…

Purpose: Proximal femur image analyses based on quantitative computed tomography (QCT) provide a method to quantify the bone density and evaluate osteoporosis and risk of fracture. We aim to develop a deep-learning-based method for…

Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…

Quantitative image reconstruction in dual-energy computed tomography (CT) remains a topic of active research. We read with interest ``DIRECT-Net: A unified mutual-domain material decomposition network for quantitative dual-energy CT…

Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…

Purpose: To investigate whether synthetically generated fractal data can be used to train deep learning (DL) models for dynamic MRI reconstruction, thereby avoiding the privacy, licensing, and availability limitations associated with…

In nuclear imaging, limited resolution causes partial volume effects (PVEs) that affect image sharpness and quantitative accuracy. Partial volume correction (PVC) methods incorporating high-resolution anatomical information from CT or MRI…

Industrial X-ray cone-beam CT (XCT) scanners are widely used for scientific imaging and non-destructive characterization. Industrial CBCT scanners use large detectors containing millions of pixels and the subsequent 3D reconstructions can…

Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of coronary artery diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-view (LV) SPECT, such as…

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

Since 2016, deep learning (DL) has advanced tomographic imaging with remarkable successes, especially in low-dose computed tomography (LDCT) imaging. Despite being driven by big data, the LDCT denoising and pure end-to-end reconstruction…

This study proposes a novel imaging and reconstruction framework for dual-energy cone-beam CT (DECBCT) using only two orthogonal X-ray projections at different energy levels (2V-DECBCT). The goal is to enable fast and low-dose DE volumetric…

Objective: This study aims at investigating a novel super resolution CBCT imaging technique with the dual-layer flat panel detector (DL-FPD). Approach: In DL-FPD based CBCT imaging, the low-energy and high-energy projections acquired from…

Recently, Self-supervised learning methods able to perform image denoising without ground truth labels have been proposed. These methods create low-quality images by adding random or Gaussian noise to images and then train a model for…

The purpose of this study was to accelerate MR cholangiopancreatography (MRCP) acquisitions using deep learning-based (DL) reconstruction at 3T and 0.55T. A total of 35 healthy volunteers underwent conventional two-fold accelerated MRCP…