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A major trend in academia and data science is the rapid adoption of Bayesian statistics for data analysis and modeling, leading to the development of probabilistic programming languages (PPL). A PPL provides a framework that allows users to…

Instrumentation and Methods for Astrophysics · Physics 2021-02-15 James. W. Nightingale , Richard G. Hayes , Matthew Griffiths

We introduce inference trees (ITs), a new class of inference methods that build on ideas from Monte Carlo tree search to perform adaptive sampling in a manner that balances exploration with exploitation, ensures consistency, and alleviates…

Ligands entering a protein binding pocket essentially compete with water molecules for binding to the protein. Hence, the location and thermodynamic properties of water molecules in protein structures have gained increased attention in the…

Biomolecules · Quantitative Biology 2019-08-28 David Schaller , Szymon Pach , Gerhard Wolber

Bayesian Knowledge Tracing, a model used for cognitive mastery estimation, has been a hallmark of adaptive learning research and an integral component of deployed intelligent tutoring systems (ITS). In this paper, we provide a brief history…

Mathematical Software · Computer Science 2021-06-01 Anirudhan Badrinath , Frederic Wang , Zachary Pardos

Despite attractive theoretical guarantees and practical successes, Predictive Interval (PI) given by Conformal Prediction (CP) may not reflect the uncertainty of a given model. This limitation arises from CP methods using a constant…

Machine Learning · Statistics 2023-06-01 Salim I. Amoukou , Nicolas J. B Brunel

Geographical random forest (GRF) is a recently developed and spatially explicit machine learning model. With the ability to provide more accurate predictions and local interpretations, GRF has already been used in many studies. The current…

Computers and Society · Computer Science 2024-09-24 Kai Sun , Ryan Zhenqi Zhou , Jiyeon Kim , Yingjie Hu

NIMS-OS (NIMS Orchestration System) is a Python library created to realize a closed loop of robotic experiments and artificial intelligence (AI) without human intervention for automated materials exploration. It uses various combinations of…

Materials Science · Physics 2026-04-30 Ryo Tamura , Koji Tsuda , Shoichi Matsuda

We present a unifying, tractable approach for studying the spread of viruses causing complex diseases requiring to be modeled using a large number of types (e.g., infective stage, clinical state, risk factor class). We show that recording…

This paper introduces PyGAD, an open-source easy-to-use Python library for building the genetic algorithm. PyGAD supports a wide range of parameters to give the user control over everything in its life cycle. This includes, but is not…

Neural and Evolutionary Computing · Computer Science 2021-06-14 Ahmed Fawzy Gad

A variety of approaches using compartmental models have been used to study the COVID-19 pandemic and the usage of machine learning methods with these models has had particularly notable success. We present here an approach toward analyzing…

Populations and Evolution · Quantitative Biology 2022-08-19 Haoran Hu , Connor M Kennedy , Panayotis G. Kevrekidis , Hongkun Zhang

Partially-observed time series (POTS) is ubiquitous in real-world applications, yet most existing toolchains separate missing-value handling from downstream learning, which limits reproducibility and overall performance. This tutorial…

Machine Learning · Computer Science 2026-04-28 Wenjie Du , Yiyuan Yang , Tianxiang Zhan , Qingsong Wen

Countries around the world implement nonpharmaceutical interventions (NPIs) to mitigate the spread of COVID-19. Design of efficient NPIs requires identification of the structure of the disease transmission network. We here identify the key…

Populations and Evolution · Quantitative Biology 2021-05-18 Simon Syga , Diana David-Rus , Yannik Schälte , Michael Meyer-Hermann , Haralampos Hatzikirou , Andreas Deutsch

The appropriateness of the Poisson model is frequently challenged when examining spatial count data marked by unbalanced distributions, over-dispersion, or under-dispersion. Moreover, traditional parametric models may inadequately capture…

Methodology · Statistics 2025-03-26 Mahsa Nadifar , Andriette Bekker , Mohammad Arashi , Abel Ramoelo

ProSper is a python library containing probabilistic algorithms to learn dictionaries. Given a set of data points, the implemented algorithms seek to learn the elementary components that have generated the data. The library widens the scope…

Signal Processing · Electrical Eng. & Systems 2019-08-20 Georgios Exarchakis , Jörg Bornschein , Abdul-Saboor Sheikh , Zhenwen Dai , Marc Henniges , Jakob Drefs , Jörg Lücke

The current landscape of scientific research is widely based on modeling and simulation, typically with complexity in the simulation's flow of execution and parameterization properties. Execution flows are not necessarily straightforward…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-26 Eduardo Ponce , Brittany Stephenson , Suzanne Lenhart , Judy Day , Gregory D. Peterson

At many scales in neuroscience, appropriate mathematical models take the form of complex dynamical systems. Parametrising such models to conform to the multitude of available experimental constraints is a global nonlinear optimisation…

Recent years have experienced increasing utilization of complex machine learning models across multiple sources of data to inform more generalizable decision-making. However, distribution shifts across data sources and privacy concerns…

Methodology · Statistics 2024-05-16 Yi Liu , Alexander W. Levis , Sharon-Lise Normand , Larry Han

Background: Clinical prediction models are increasingly used to inform healthcare decisions, but determining the minimum sample size for their development remains a critical and unresolved challenge. Inadequate sample sizes can lead to…

Machine Learning · Computer Science 2026-03-02 Diana Shamsutdinova , Felix Zimmer , Oyebayo Ridwan Olaniran , Sarah Markham , Daniel Stahl , Gordon Forbes , Ewan Carr

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

We focus on the problem of uncertainty informed allocation of medical resources (vaccines) to heterogeneous populations for managing epidemic spread. We tackle two related questions: (1) For a compartmental ordinary differential equation…

Optimization and Control · Mathematics 2023-07-04 Samarth Gupta , Saurabh Amin
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