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Current state-of-the-art deep learning segmentation methods have not yet made a broad entrance into the clinical setting in spite of high demand for such automatic methods. One important reason is the lack of reliability caused by models…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Jörg Sander , Bob D. de Vos , Jelmer M. Wolterink , Ivana Išgum

Deep learning has shown tremendous progress in a wide range of digital pathology and medical image classification tasks. Its integration into safe clinical decision-making support requires robust and reliable models. However, real-world…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abdur R. Fayjie , Jutika Borah , Florencia Carbone , Jan Tack , Patrick Vandewalle

In the United States, heart disease is the leading cause of death for both men and women, accounting for 610,000 deaths each year [1]. Physicians use Magnetic Resonance Imaging (MRI) scans to take images of the heart in order to…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Ehab Abdelmaguid , Jolene Huang , Sanjay Kenchareddy , Disha Singla , Laura Wilke , Mai H. Nguyen , Ilkay Altintas

EEG decoding systems based on deep neural networks have been widely used in decision making of brain computer interfaces (BCI). Their predictions, however, can be unreliable given the significant variance and noise in EEG signals. Previous…

Signal Processing · Electrical Eng. & Systems 2022-10-04 Tiehang Duan , Zhenyi Wang , Sheng Liu , Sargur N. Srihari , Hui Yang

Segmentation tasks in medical imaging are inherently ambiguous: the boundary of a target structure is oftentimes unclear due to image quality and biological factors. As such, predicted segmentations from deep learning algorithms are…

Image and Video Processing · Electrical Eng. & Systems 2019-11-18 Katharina Hoebel , Ken Chang , Jay Patel , Praveer Singh , Jayashree Kalpathy-Cramer

Deep learning based methods for automatic organ segmentation have shown promise in aiding diagnosis and treatment planning. However, quantifying and understanding the uncertainty associated with model predictions is crucial in critical…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Jadie Adams , Shireen Y. Elhabian

Accurate medical image segmentation is crucial for diagnosis and analysis. However, the models without calibrated uncertainty estimates might lead to errors in downstream analysis and exhibit low levels of robustness. Estimating the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Yanwu Yang , Xutao Guo , Yiwei Pan , Pengcheng Shi , Haiyan Lv , Ting Ma

We address the selection and evaluation of uncertain segmentation methods in medical imaging and present two case studies: prostate segmentation, illustrating that for minimal annotator variation simple deterministic models can suffice, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Kilian Zepf , Jes Frellsen , Aasa Feragen

Echocardiography image quality assessment is not a trivial issue in transthoracic examination. As the in vivo examination of heart structures gained prominence in cardiac diagnosis, it has been affirmed that accurate diagnosis of the left…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Robert B. Labs , Massoud Zolgharni , Jonathan P. Loo

Uncertainty quantification in medical images has become an essential addition to segmentation models for practical application in the real world. Although there are valuable developments in accurate uncertainty quantification methods using…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Christiaan G. A. Viviers , Amaan M. M. Valiuddin , Peter H. N. de With , Fons van der Sommen

The ability of deep learning to predict with uncertainty is recognized as key for its adoption in clinical routines. Moreover, performance gain has been enabled by modelling uncertainty according to empirical evidence. While previous work…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jiawei Yang , Yuan Liang , Yao Zhang , Weinan Song , Kun Wang , Lei He

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

Reliable MRI is crucial for accurate interpretation in therapeutic and diagnostic tasks. However, undersampling during MRI acquisition as well as the overparameterized and non-transparent nature of deep learning (DL) leaves substantial…

Computer Vision and Pattern Recognition · Computer Science 2020-04-28 Vineet Edupuganti , Morteza Mardani , Shreyas Vasanawala , John Pauly

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

In medical image segmentation, uncertainty estimates are often reported but rarely used to guide decisions. We study the missing step: how uncertainty maps are converted into actionable policies such as accepting, flagging, or deferring…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Saket Maganti

Distribution shift is an important concern in deep image classification, produced either by corruption of the source images, or a complete change, with the solution involving domain adaptation. While the primary goal is to improve accuracy…

Machine Learning · Statistics 2021-10-19 Tiago Salvador , Vikram Voleti , Alexander Iannantuono , Adam Oberman

Electrocardiogram (ECG) is a widely used reliable, non-invasive approach for cardiovascular disease diagnosis. With the rapid growth of ECG examinations and the insufficiency of cardiologists, accurate and automatic diagnosis of ECG signals…

Machine Learning · Computer Science 2020-10-21 Dongdong Zhang , Xiaohui Yuan , Ping Zhang

The standard electrocardiogram (ECG) is a point-wise evaluation of the body potential at certain given locations. These locations are subject to uncertainty and may vary from patient to patient or even for a single patient. In this work, we…

Numerical Analysis · Mathematics 2021-04-20 Michael Multerer , Simone Pezzuto

Medical images are increasingly used as input to deep neural networks to produce quantitative values that aid researchers and clinicians. However, standard deep neural networks do not provide a reliable measure of uncertainty in those…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jacob C. Reinhold , Yufan He , Shizhong Han , Yunqiang Chen , Dashan Gao , Junghoon Lee , Jerry L. Prince , Aaron Carass

Deep learning-based methods have spearheaded the automatic analysis of echocardiographic images, taking advantage of the publication of multiple open access datasets annotated by experts (CAMUS being one of the largest public databases).…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Hang Jung Ling , Nathan Painchaud , Pierre-Yves Courand , Pierre-Marc Jodoin , Damien Garcia , Olivier Bernard