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Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the…

Machine Learning · Computer Science 2019-02-14 Benjamin Shickel , Tyler J. Loftus , Lasith Adhikari , Tezcan Ozrazgat-Baslanti , Azra Bihorac , Parisa Rashidi

Coding diagnosis and procedures in medical records is a crucial process in the healthcare industry, which includes the creation of accurate billings, receiving reimbursements from payers, and creating standardized patient care records. In…

Computation and Language · Computer Science 2020-01-01 Siddhartha Nuthakki , Sunil Neela , Judy W. Gichoya , Saptarshi Purkayastha

Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…

Machine Learning · Computer Science 2024-03-28 Bar Eini Porat , Danny Eytan , Uri Shalit

Objective: Clinical notes contain information not present elsewhere, including drug response and symptoms, all of which are highly important when predicting key outcomes in acute care patients. We propose the automatic annotation of…

Computation and Language · Computer Science 2021-11-25 Jingqing Zhang , Luis Bolanos , Ashwani Tanwar , Julia Ive , Vibhor Gupta , Yike Guo

Background: Hypertensive kidney disease (HKD) patients in intensive care units (ICUs) face high short-term mortality, but tailored risk prediction tools are lacking. Early identification of high-risk individuals is crucial for clinical…

Machine Learning · Computer Science 2025-07-28 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Background: Patients with both diabetes mellitus (DM) and atrial fibrillation (AF) face elevated mortality in intensive care units (ICUs), yet models targeting this high-risk group remain limited. Objective: To develop an interpretable…

Machine Learning · Computer Science 2025-06-23 Li Sun , Shuheng Chen , Yong Si , Junyi Fan , Maryam Pishgar , Elham Pishgar , Kamiar Alaei , Greg Placencia

Prediction of mortality in intensive care unit (ICU) patients typically relies on black box models (that are unacceptable for use in hospitals) or hand-tuned interpretable models (that might lead to the loss in performance). We aim to…

Machine Learning · Computer Science 2025-01-09 Chloe Qinyu Zhu , Muhang Tian , Lesia Semenova , Jiachang Liu , Jack Xu , Joseph Scarpa , Cynthia Rudin

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

Machine Learning · Computer Science 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi

Accurate early prediction of in-hospital mortality in intensive care units (ICUs) is essential for timely clinical intervention and efficient resource allocation. This study develops and evaluates machine learning models that integrate both…

Machine Learning · Computer Science 2025-10-22 Nursultan Mamatov , Philipp Kellmeyer

Early prediction of in-hospital mortality in critically ill patients can aid clinicians in optimizing treatment. The objective was to develop a multimodal deep learning model, using structured and unstructured clinical data, to predict…

Machine Learning · Computer Science 2025-12-24 Behrooz Mamandipoor , Chun-Nan Hsu , Martin Krause , Ulrich H. Schmidt , Rodney A. Gabriel

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Healthcare data continues to flourish yet a relatively small portion, mostly structured, is being utilized effectively for predicting clinical outcomes. The rich subjective information available in unstructured clinical notes can possibly…

Machine Learning · Computer Science 2019-11-20 Mohammad Hashir , Rapinder Sawhney

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

Computation and Language · Computer Science 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

Sepsis is a leading cause of mortality in intensive care units (ICUs), representing a substantial medical challenge. The complexity of analyzing diverse vital signs to predict sepsis further aggravates this issue. While deep learning…

Machine Learning · Computer Science 2024-05-24 Yuwei Liu , Chen Dan , Anubhav Bhatti , Bingjie Shen , Divij Gupta , Suraj Parmar , San Lee

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Heart failure affects millions of people worldwide, significantly reducing quality of life and leading to high mortality rates. Despite extensive research, the relationship between heart failure and mortality rates among ICU patients is not…

Machine Learning · Computer Science 2024-09-04 Negin Ashrafi , Armin Abdollahi , Jiahong Zhang , Maryam Pishgar

Good predictors of ICU Mortality have the potential to identify high-risk patients earlier, improve ICU resource allocation, or create more accurate population-level risk models. Machine learning practitioners typically make choices about…

Artificial Intelligence · Computer Science 2016-02-09 Harini Suresh

Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the…

Machine Learning · Computer Science 2017-07-18 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

Clinical text provides essential information to estimate the acuity of a patient during hospital stays in addition to structured clinical data. In this study, we explore how clinical text can complement a clinical predictive learning task.…