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Medical imaging diagnosis increasingly relies on Machine Learning (ML) models. This is a task that is often hampered by severely imbalanced datasets, where positive cases can be quite rare. Their use is further compromised by their limited…

Machine Learning · Computer Science 2024-01-26 Yumnah Hasan , Allan de Lima , Fatemeh Amerehi , Darian Reyes Fernandez de Bulnes , Patrick Healy , Conor Ryan

The number of scientific papers grows exponentially in many disciplines. The share of online available papers grows as well. At the same time, the period of time for a paper to loose at chance to be cited anymore shortens. The decay of the…

Computation and Language · Computer Science 2016-01-11 Rustam Tagiew

We aim to automatically generate natural language descriptions about an input structured knowledge base (KB). We build our generation framework based on a pointer network which can copy facts from the input KB, and add two attention…

Computation and Language · Computer Science 2020-11-03 Qingyun Wang , Xiaoman Pan , Lifu Huang , Boliang Zhang , Zhiying Jiang , Heng Ji , Kevin Knight

Knowledge hypergraphs surpass traditional binary knowledge graphs by encapsulating complex $n$-ary atomic facts, providing a more comprehensive paradigm for semantic representation. However, constructing high-quality hypergraphs remains…

Computation and Language · Computer Science 2026-02-24 Rizhuo Huang , Yifan Feng , Rundong Xue , Shihui Ying , Jun-Hai Yong , Chuan Shi , Shaoyi Du , Yue Gao

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

Artificial Intelligence · Computer Science 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

Open Domain Question Answering (QA) is evolving from complex pipelined systems to end-to-end deep neural networks. Specialized neural models have been developed for extracting answers from either text alone or Knowledge Bases (KBs) alone.…

Computation and Language · Computer Science 2018-09-05 Haitian Sun , Bhuwan Dhingra , Manzil Zaheer , Kathryn Mazaitis , Ruslan Salakhutdinov , William W. Cohen

Emerging topics in biomedical research are continuously expanding, providing a wealth of information about genes and their function. This rapid proliferation of knowledge presents unprecedented opportunities for scientific discovery and…

Genomics · Quantitative Biology 2024-12-25 Zhijian Chen , Chuan Hu , Min Wu , Qingqing Long , Xuezhi Wang , Yuanchun Zhou , Meng Xiao

Machine learning is bringing a paradigm shift to healthcare by changing the process of disease diagnosis and prognosis in clinics and hospitals. This development equips doctors and medical staff with tools to evaluate their hypotheses and…

Black box deep learning models trained on genomic sequences excel at predicting the outcomes of different gene regulatory mechanisms. Therefore, interpreting these models may provide novel insights into the underlying biology, supporting…

Machine Learning · Computer Science 2024-07-18 Pedro Barbosa , Rosina Savisaar , Alcides Fonseca

While we once thought of cancer as single monolithic diseases affecting a specific organ site, we now understand that there are many subtypes of cancer defined by unique patterns of gene mutations. These gene mutational data, which can be…

Quantitative Methods · Quantitative Biology 2017-03-07 Jipeng Qiang , Wei Ding , John Quackenbush , Ping Chen

Automated text generation requires a underlying knowledge base from which to generate, which is often difficult to produce. Software documentation is one domain in which parts of this knowledge base may be derived automatically. In this…

cmp-lg · Computer Science 2008-02-03 Cecile Paris , Keith Vander Linden

With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace that creates challenges when physicians try…

Recent advances in the healthcare industry have led to an abundance of unstructured data, making it challenging to perform tasks such as efficient and accurate information retrieval at scale. Our work offers an all-in-one scalable solution…

Information Retrieval · Computer Science 2023-02-15 Shreya Saxena , Raj Sangani , Siva Prasad , Shubham Kumar , Mihir Athale , Rohan Awhad , Vishal Vaddina

Statistical inference on the cancer-site specificities of collective ultra-rare whole genome somatic mutations is an open problem. Traditional statistical methods cannot handle whole-genome mutation data due to their…

Methodology · Statistics 2023-01-02 Saptarshi Chakraborty , Zoe Guan , Colin B. Begg , Ronglai Shen

Extracting useful signals or pattern to support important business decisions for example analyzing investment product traction and discovering customer preference, risk monitoring etc. from unstructured text is a challenging task. Capturing…

Computation and Language · Computer Science 2025-06-03 Anshika Rawal , Abhijeet Kumar , Mridul Mishra

Knowledge base is the way to store structured and unstructured data throughout the web. Since the size of the web is increasing rapidly, there are huge needs to structure the knowledge in a fully automated way. However fully-automated…

Artificial Intelligence · Computer Science 2016-04-05 Sundong Kim

Benchmarking drug efficacy is a critical step in clinical trial design and planning. The challenge is that much of the data on efficacy endpoints is stored in scientific papers in free text form, so extraction of such data is currently a…

The conventional process of building Ontologies and Knowledge Graphs (KGs) heavily relies on human domain experts to define entities and relationship types, establish hierarchies, maintain relevance to the domain, fill the ABox (or populate…

Computation and Language · Computer Science 2024-03-14 Vamsi Krishna Kommineni , Birgitta König-Ries , Sheeba Samuel

Feature selection in Knowledge Graphs (KGs) are increasingly utilized in diverse domains, including biomedical research, Natural Language Processing (NLP), and personalized recommendation systems. This paper delves into the methodologies…

Machine Learning · Computer Science 2024-06-24 Sisi Shao , Pedro Henrique Ribeiro , Christina Ramirez , Jason H. Moore

Discovery gene-disease links is important in biology and medicine areas, enabling disease identification and drug repurposing. Machine learning approaches accelerate this process by leveraging biological knowledge represented in ontologies…

Machine Learning · Computer Science 2025-04-14 Catarina Canastra , Cátia Pesquita