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This article reports a first update on the assesment of the model previously presented in arXiv:2003.13890v1. New available data have been used to feed the model and the comparison with real data still shows good agreement. The main novelty…

Populations and Evolution · Quantitative Biology 2020-04-14 Efren M. Benavides

Accurate numbers are needed to understand and predict viral dynamics. Curation of high-quality literature values for the infectious period duration or household secondary attack rate, for example, is especially pressing currently because…

Other Quantitative Biology · Quantitative Biology 2020-07-10 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

Reporting test-retest reliability using the intraclass correlation coefficient (ICC) has received increasing attention due to the criticisms of poor transparency and replicability in neuroimaging research, as well as many other biomedical…

Methodology · Statistics 2026-01-07 Yufeng Liu , Xiangfei Hong , Shanbao Tong

Breaking a complex bio-social phenomenon (epidemic) into its components, considering the processes that determine its dynamics, formalizing the accepted hypotheses in mathematical equations, selecting appropriate experimental and…

Physics and Society · Physics 2020-06-16 A. V. Sokolov , L. A. Sokolova

Estimating prevalence, the fraction of a population with a certain medical condition, is fundamental to epidemiology. Traditional methods rely on classification of test samples taken at random from a population. Such approaches to…

Methodology · Statistics 2022-03-25 Paul Patrone , Anthony Kearsley

In this paper, we show that many structured epidemic models may be described using a straightforward product structure. Such products, derived from products of directed graphs, may represent useful refinements including geographic and…

Populations and Evolution · Quantitative Biology 2017-06-30 Lee Worden , Travis C. Porco

Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…

This article reviews quantitative methods to estimate the basic reproduction number of pandemic influenza, a key threshold quantity to help determine the intensity of interventions required to control the disease. Although it is difficult…

Populations and Evolution · Quantitative Biology 2009-11-13 Gerardo Chowell , Hiroshi Nishiura

If model identifiability is not confirmed, inferences from infectious disease transmission models may not be reliable, so they might lead to misleading recommendations. Structural identifiability analysis characterizes whether it is…

Quantitative Methods · Quantitative Biology 2022-06-09 Emmanuelle A. Dankwa , Andrew F. Brouwer , Christl A. Donnelly

Many countries have established population-based biobanks, which are being used increasingly in epidemiolgical and clinical research. These biobanks offer opportunities for large-scale studies addressing questions beyond the scope of…

Methodology · Statistics 2024-03-28 Malka Gorfine , David M. Zucker , Shoval Shoham

Over the course of the COVID-19 pandemic, Generalised Additive Models (GAMs) have been successfully employed on numerous occasions to obtain vital data-driven insights. In this paper we further substantiate the success story of GAMs,…

We present a new analysis of relationships between disease incidence and the prevalence of an experimentally defined state of `recent infection'. This leads to a clean separation between biological parameters (properties of disease…

Populations and Evolution · Quantitative Biology 2008-06-09 Thomas A. McWalter , Alex Welte

The accurate estimation of time-varying transmission rates is fundamental for understanding infectious disease dynamics and implementing effective public health interventions. To this end, we propose an improved inverse method for…

Populations and Evolution · Quantitative Biology 2025-12-17 Shuanglin Jing , Yuting Huang , Hai-Feng Huo

Our main goal is to examine the role of communities in epidemic spread in a random graph model. More precisely, we consider a random graph model which consists of overlapping complete graphs, representing households, workplaces, school…

Physics and Society · Physics 2023-08-25 Ágnes Backhausz , György J. Székely

Interval identification of parameters such as average treatment effects, average partial effects and welfare is particularly common when using observational data and experimental data with imperfect compliance due to the endogeneity of…

Econometrics · Economics 2025-04-09 Sukjin Han , Adam McCloskey

In epidemiological studies, the capture-recapture (CRC) method is a powerful tool that can be used to estimate the number of diseased cases or potentially disease prevalence based on data from overlapping surveillance systems. Estimators…

Applications · Statistics 2023-06-21 Yuzi Zhang , Lin Ge , Lance A. Waller , Robert H. Lyles

Epidemiological compartmental models are useful for understanding infectious disease propagation and directing public health policy decisions. Calibration of these models is an important step in offering accurate forecasts of disease…

Machine Learning · Computer Science 2023-12-12 Nikunj Gupta , Anh Mai , Azza Abouzied , Dennis Shasha

Mathematical modeling has played a central role in understanding how infectious disease transmission manifests in populations. These models have demonstrated the importance of key community-level factors in structuring epidemic risk, and…

Quantitative Methods · Quantitative Biology 2025-06-27 Sudam Surasinghe , Swathi Nachiar Manivannan , Samuel V. Scarpino , Lorin Crawford , C. Brandon Ogbunugafor

I employ a simple mathematical model of an epidemic process to evaluate how four basic quantities: the reproduction number (R), the numbers of sensitive (S) and infectious individuals(I), and total community size (N) affect strategies to…

Populations and Evolution · Quantitative Biology 2020-05-08 Michael E. Hochberg

Beneficial to advanced computing devices, models with massive parameters are increasingly employed to extract more information to enhance the precision in describing and predicting the patterns of objective systems. This phenomenon is…

Information Theory · Computer Science 2024-03-08 Liye Jia , Fengyufan Yang , Ka Lok Man , Erick Purwanto , Sheng-Uei Guan , Jeremy Smith , Yutao Yue