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In the realm of neuroscience, identifying distinctive patterns associated with neurological disorders via brain networks is crucial. Resting-state functional magnetic resonance imaging (fMRI) serves as a primary tool for mapping these…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Jiaxing Xu , Mengcheng Lan , Xia Dong , Kai He , Wei Zhang , Qingtian Bian , Yiping Ke

Scientists construct connectomes, comprehensive descriptions of neuronal connections across a brain, in order to better understand and model brain function. Interactive visualizations of these pathways would enable exploratory analysis of…

Neurons and Cognition · Quantitative Biology 2022-05-06 Seth Daetwiler , Angus Read , Jessica Stillwell , Kameron Decker Harris

Diffusion MRI (dMRI) is a critical non-invasive technique to estimate fiber orientation distribution (FOD) for characterizing white matter integrity. Estimating FOD from single-shell low angular resolution dMRI (LAR-FOD) is limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Hao Tang , Hanyu Liu , Alessandro Perelli , Xi Chen , Chao Li

Functional magnetic resonance imaging (fMRI) time series data presents a unique opportunity to understand the behavior of temporal brain connectivity, and models that uncover the complex dynamic workings of this organ are of keen interest…

Methodology · Statistics 2024-01-22 Martin Ondrus , Emily Olds , Ivor Cribben

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Jihoon Cho , Suhyun Ahn , Beomju Kim , Hyungjoon Bae , Xiaofeng Liu , Fangxu Xing , Kyungeun Lee , Georges Elfakhri , Van Wedeen , Jonghye Woo , Jinah Park

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato

Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs) that describe the distribution, direction, and volume of…

In many laboratories, conventional bright-field transmission microscopes are available to study the structure and organization principles of fibrous tissue samples, but they usually provide only 2D information. To access the third…

Tractography traces the peak directions extracted from fiber orientation distribution (FOD) suffering from ambiguous spatial correspondences between diffusion directions and fiber geometry, which is prone to producing erroneous tracks while…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Yuanjing Feng , Lei Xie , Jingqiang Wang , Qiyuan Tian , Jianzhong He , Qingrun Zeng , Fei Gao

The anatomical structure of the brain can be observed via non-invasive techniques such as diffusion imaging. However, these are imperfect because they miss connections that are actually known to exist, especially long range…

Neurons and Cognition · Quantitative Biology 2015-02-25 Somwrita Sarkar , Sanjay Chawla , Donna Xu

Brain fiber tracts are widely used in studying brain diseases, which may lead to a better understanding of how disease affects the brain. The segmentation of brain fiber tracts assumed enormous importance in disease analysis. In this paper,…

Neurons and Cognition · Quantitative Biology 2020-11-04 Chaoqing Xu , Guodao Sun , Ronghua Liang , Xiufang Xu

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

Reconstructing visual stimuli from functional Magnetic Resonance Imaging fMRI enables fine-grained retrieval of brain activity. However, the accurate reconstruction of diverse details, including structure, background, texture, color, and…

Neural and Evolutionary Computing · Computer Science 2025-01-09 Haoyu Li , Hao Wu , Badong Chen

Functional connectivity estimates are highly sensitive to analysis choices and can be dominated by noise when the number of sampled time points is small relative to network dimensionality. This issue is particularly acute in fMRI, where…

Disordered Systems and Neural Networks · Physics 2026-02-10 Izaro Fernandez-Iriondo , Antonio Jimenez-Marin , Jesus Cortes , Pablo Villegas

We present DeepTract, a deep-learning framework for estimating white matter fibers orientation and streamline tractography. We adopt a data-driven approach for fiber reconstruction from diffusion weighted images (DWI), which does not assume…

Computer Vision and Pattern Recognition · Computer Science 2019-10-18 Itay Benou , Tammy Riklin-Raviv

We present a novel dual-encoded magnetization transfer (MT) and diffusion-weighted sequence and demonstrate its potential to resolve distinct properties of white matter fiber tracts at the sub-voxel level. The sequence was designed and…

So far, fingerprinting studies have focused on identifying features from single-modality MRI data, which capture individual characteristics in terms of brain structure, function, or white matter microstructure. However, due to the lack of a…

Computer Vision and Pattern Recognition · Computer Science 2017-09-20 Kuldeep Kumar , Laurent Chauvin , Mathew Toews , Olivier Colliot , Christian Desrosiers

We present the concept of fiber-flux density for locally quantifying white matter (WM) fiber bundles. By combining scalar diffusivity measures (e.g., fractional anisotropy) with fiber-flux measurements, we define new local descriptors…

Computer Vision and Pattern Recognition · Computer Science 2017-09-20 Itay Benou , Ronel Veksler , Alon Friedman , Tammy Riklin Raviv