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The graph alignment problem, which considers the optimal node correspondence across networks, has recently gained significant attention due to its wide applications. There are graph alignment methods suited for various network types, but we…

Social and Information Networks · Computer Science 2025-05-15 Ashley Wang , Peter Chin

Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…

Multimodal knowledge graphs (MMKGs) enrich traditional knowledge graphs (KGs) by incorporating diverse modalities such as images and text. multimodal knowledge graph completion (MMKGC) seeks to exploit these heterogeneous signals to infer…

Computation and Language · Computer Science 2025-08-12 Yongkang Xiao , Rui Zhang

Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the…

Machine Learning · Computer Science 2018-12-27 Anees Kazi , S. Arvind krishna , Shayan Shekarforoush , Karsten Kortuem , Shadi Albarqouni , Nassir Navab

Objective: Modern medicine needs to shift from a wait and react, curative discipline to a preventative, interdisciplinary science aiming at providing personalised, systemic and precise treatment plans to patients. The aim of this work is to…

Machine Learning · Statistics 2020-09-18 Pietro Barbiero , Ramon Viñas Torné , Pietro Lió

Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of…

Quantitative Methods · Quantitative Biology 2017-05-23 Peng Yang

Every day, poison control centers (PCC) are called for immediate classification and treatment recommendations if an acute intoxication is suspected. Due to the time-sensitive nature of these cases, doctors are required to propose a correct…

Fault diagnosis is important to the design and maintenance of large multiprocessor systems. PMC model is the most famous diagnosis model in the system level diagnosis of multiprocessor systems. Under the PMC model, only node faults are…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-09-20 Qiang Zhu

Understanding the relationships between different properties of data, such as whether a connectome or genome has information about disease status, is becoming increasingly important in modern biological datasets. While existing approaches…

Machine Learning · Statistics 2024-06-27 Joshua T. Vogelstein , Eric Bridgeford , Qing Wang , Carey E. Priebe , Mauro Maggioni , Cencheng Shen

Label Distribution Learning (LDL) is a novel machine learning paradigm that addresses the problem of label ambiguity and has found widespread applications. Obtaining complete label distributions in real-world scenarios is challenging, which…

Machine Learning · Computer Science 2024-10-18 Zhiqiang Kou , Haoyuan Xuan , Jing Wang , Yuheng Jia , Xin Geng

Multimodal fusion benefits disease diagnosis by providing a more comprehensive perspective. Developing algorithms is challenging due to data heterogeneity and the complex within- and between-modality associations. Deep-network-based…

Neurons and Cognition · Quantitative Biology 2020-06-18 Wenxing Hu , Xianghe Meng , Yuntong Bai , Aiying Zhang , Biao Cai , Gemeng Zhang , Tony W. Wilson , Julia M. Stephen , Vince D. Calhoun , Yu-Ping Wang

Predicting whether subjects with mild cognitive impairment (MCI) will convert to Alzheimer's disease is a significant clinical challenge. Longitudinal variations and complementary information inherent in longitudinal and multimodal data are…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Tao Wang , Xiumei Chen , Xiaoling Zhang , Shuoling Zhou , Qianjin Feng , Meiyan Huang

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Multi-modal knowledge graphs (MKGs) include not only the relation triplets, but also related multi-modal auxiliary data (i.e., texts and images), which enhance the diversity of knowledge. However, the natural incompleteness has…

Artificial Intelligence · Computer Science 2022-09-07 Shangfei Zheng , Weiqing Wang , Jianfeng Qu , Hongzhi Yin , Wei Chen , Lei Zhao

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide…

Image and Video Processing · Electrical Eng. & Systems 2021-02-11 Riqiang Gao , Yucheng Tang , Kaiwen Xu , Michael N. Kammer , Sanja L. Antic , Steve Deppen , Kim L. Sandler , Pierre P. Massion , Yuankai Huo , Bennett A. Landman

BACKGROUND: As databases grow larger, it becomes harder to fully control their collection, and they frequently come with missing values: incomplete observations. These large databases are well suited to train machine-learning models, for…

Machine Learning · Computer Science 2022-02-23 Alexandre Perez-Lebel , Gaël Varoquaux , Marine Le Morvan , Julie Josse , Jean-Baptiste Poline

The emergence of medical generalist foundation models has revolutionized conventional task-specific model development paradigms, aiming to better handle multiple tasks through joint training on large-scale medical datasets. However, recent…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Xun Zhu , Fanbin Mo , Zheng Zhang , Jiaxi Wang , Yiming Shi , Ming Wu , Chuang Zhang , Miao Li , Ji Wu

Major depressive disorder is a serious and heterogeneous psychiatric disorder that needs accurate diagnosis. Resting-state functional MRI (rsfMRI), which captures multiple perspectives on brain structure, function, and connectivity, is…

Machine Learning · Computer Science 2023-08-21 Yunsong Luo , Wenyu Chen , Ling Zhan , Jiang Qiu , Tao Jia

Bridging the gap between internal and external validity is crucial for heterogeneous treatment effect estimation. Randomised controlled trials (RCTs), favoured for their internal validity due to randomisation, often encounter challenges in…

Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support systems. Over the past decade, numerous architectures specifically tailored to medical imaging have emerged to address…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Vanessa Borst , Samuel Kounev