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This paper presents NimbleReg, a light-weight deep-learning (DL) framework for diffeomorphic image registration leveraging surface representation of multiple segmented anatomical regions. Deep learning has revolutionized image registration…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Antoine Legouhy , Ross Callaghan , Nolah Mazet , Vivien Julienne , Hojjat Azadbakht , Hui Zhang

Background: Automated segmentation of spinal MR images plays a vital role both scientifically and clinically. However, accurately delineating posterior spine structures presents challenges. Methods: This retrospective study, approved by the…

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

Estimated brain age from magnetic resonance image (MRI) and its deviation from chronological age can provide early insights into potential neurodegenerative diseases, supporting early detection and implementation of prevention strategies.…

In this paper, we propose a method for denoising diffusion-weighted images (DWI) of the brain using a convolutional neural network trained on realistic, synthetic MR data. We compare our results to averaging of repeated scans, a widespread…

Image and Video Processing · Electrical Eng. & Systems 2022-06-02 Jakub Jurek , Andrzej Materka , Kamil Ludwisiak , Agata Majos , Kamil Gorczewski , Kamil Cepuch , Agata Zawadzka

Medical image registration drives quantitative analysis across organs, modalities, and patient populations. Recent deep learning methods often combine low-level "trend-driven" computational blocks from computer vision, such as large-kernel…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Bailiang Jian , Jiazhen Pan , Rohit Jena , Morteza Ghahremani , Hongwei Bran Li , Daniel Rueckert , Christian Wachinger , Benedikt Wiestler

Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to…

Machine Learning · Statistics 2016-02-01 Thien Bao Nguyen , Emanuele Olivetti , Paolo Avesani

Denosing diffusion model, as a generative model, has received a lot of attention in the field of image generation recently, thanks to its powerful generation capability. However, diffusion models have not yet received sufficient research in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 ZiHan Cao , ShiQi Cao , Xiao Wu , JunMing Hou , Ran Ran , Liang-Jian Deng

The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

Text-to-image (T2I) generative models have recently emerged as a powerful tool, enabling the creation of photo-realistic images and giving rise to a multitude of applications. However, the effective integration of T2I models into…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Zhicai Wang , Longhui Wei , Tan Wang , Heyu Chen , Yanbin Hao , Xiang Wang , Xiangnan He , Qi Tian

Diffeomorphic image registration is a fundamental step in medical image analysis, owing to its capability to ensure the invertibility of transformations and preservation of topology. Currently, unsupervised learning-based registration…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jiong Wu , Shuang Zhou , Li Lin , Xin Wang , Wenxue Tan

Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Ana Lawry Aguila , Dina Zemlyanker , You Cheng , Sudeshna Das , Daniel C. Alexander , Oula Puonti , Annabel Sorby-Adams , W. Taylor Kimberly , Juan Eugenio Iglesias

Current fMRI foundation models primarily rely on a limited range of brain states and mismatched pretraining tasks, restricting their ability to learn generalized representations across diverse brain states. We present \textit{Brain-DiT}, a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Junfeng Xia , Wenhao Ye , Xuanye Pan , Xinke Shen , Mo Wang , Quanying Liu

Accurate segmentation of ischemic stroke lesions from diffusion magnetic resonance imaging (MRI) is essential for clinical decision-making and outcome assessment. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-24 Muhammad Usman , Azka Rehman , Muhammad Mutti Ur Rehman , Abd Ur Rehman , Muhammad Umar Farooq

With the rapid development of imaging sensor technology in the field of remote sensing, multi-modal remote sensing data fusion has emerged as a crucial research direction for land cover classification tasks. While diffusion models have made…

Computer Vision and Pattern Recognition · Computer Science 2024-01-08 DaiXun Li , Weiying Xie , ZiXuan Wang , YiBing Lu , Yunsong Li , Leyuan Fang

Diffusion models demonstrate remarkable capabilities in capturing complex data distributions and have achieved compelling results in many generative tasks. While they have recently been extended to dense prediction tasks such as depth…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Haorui Ji , Taojun Lin , Hongdong Li

Discriminative classifiers have become a foundational tool in deep learning for medical imaging, excelling at learning separable features of complex data distributions. However, these models often need careful design, augmentation, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Gian Mario Favero , Parham Saremi , Emily Kaczmarek , Brennan Nichyporuk , Tal Arbel

Diffeomorphic image registration (DIR) is a fundamental task in 3D medical image analysis that seeks topology-preserving deformations between image pairs. To ensure diffeomorphism, a common approach is to model the deformation field as the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Mohammadjavad Matinkia , Nilanjan Ray

In this paper, a new variational model with fractional-order regularization term arising in registration of diffusion tensor image(DTI) is presented. Moreover, the existence of its solution is proved to ensure that there is a regular…

Functional Analysis · Mathematics 2017-02-28 Huan Han

Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are…

Medical Physics · Physics 2020-08-14 Valerij G. Kiselev