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Optical spectroscopy and imaging of microscopic samples have opened up a wide range of applications throughout the physical, chemical, and biological sciences. High chemical specificity may be achieved by directly interrogating the…

Coherent Raman scattering (CRS) spectroscopy techniques have been widely developed and optimized for different applications in biomedicine and fundamental science. The most utilized CRS technique has been coherent anti-Stokes Raman…

Optics · Physics 2020-03-05 Pavel Kolesnichenko , Jonathan O. Tollerud , Jeffrey A. Davis

Raman spectroscopy is one of the key techniques in the study of vibrational modes and molecular structures. In Coherent Anti-Stokes Raman Scattering (CARS) spectroscopy, a molecular vibrational spectrum is resolved via the third-order…

Optics · Physics 2010-12-02 Ori Katz , Jonathan M. Levitt , Eran Grinvald , Yaron Silberberg

We demonstrate coherent anti-Stokes Raman scattering (CARS) microscopy with 1089 foci, enabled by a high repetition rate amplified oscillator and optical parametric amplifier. We employ a camera as multichannel detector to acquire and…

Optics · Physics 2024-08-27 Dominykas Gudavicius , Lukas Kontenis , Wolfgang Langbein

Chemical imaging enabled by Raman processes is crucial to investigating biological and chemical samples in a label-free manner. Stimulated Raman spectroscopy (SRS) overcomes the key limitation associated with low signal levels in…

Optics · Physics 2026-03-25 Florian M. Schweizer , Hannah Terrasa , Manish Garg

We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique…

The ability to enhance resonant signals and eliminate the non-resonant background is analyzed for Coherent Anti-Stokes Raman Scattering (CARS). The analysis is done at a specific frequency as well as for broadband excitation using…

Quantum Physics · Physics 2015-03-19 Fang Gao , Feng Shuang , JunHui Shi , Herschel Rabitz , HaiFeng Wang , JiXin Cheng

Surface-enhanced coherent anti-Stokes Raman scattering (SE-CARS) takes advantage of surface plasmon resonances supported on metallic nanostructures to amplify the coherent Raman response of target molecules. While these metallic antennas…

Optics · Physics 2022-09-07 Shamsul Abedin , Yong Li , Abid Anjum Sifat , Khokan Roy , Eric Olaf Potma

A major impediment of using Coherent Anti-Stokes Raman Scattering to identify biological molecules is that the illumination levels required to produce a measurable signal often also produce significant nonresonant background from the…

We report stimulated Raman spectroscopy of the G phonon in both single and multi-layer graphene, through Coherent anti-Stokes Raman Scattering (CARS). The signal generated by the third order nonlinearity is dominated by a vibrationally…

Mesoscale and Nanoscale Physics · Physics 2019-09-11 A. Virga , C. Ferrante , G. Batignani , D. De Fazio , A. D. G. Nunn , A. C. Ferrari , G. Cerullo , T. Scopigno

We propose a full-vectorial numerical study of far field radiation patterns in coherent anti-Stokes Raman scattering (CARS) microscopy. We emphasis the particular role of the Raman depolarisation ratio of the observed medium and show how it…

Optics · Physics 2009-11-13 D. Gachet , N. Sandeau , H. Rigneault

Coherent anti-Stokes Raman scattering (CARS) microscope system was built and applied to a non-intrusive gas concentration measurement of a mixing flow in a millimeter-scale channel. Carbon dioxide and nitrogen were chosen as test fluids and…

Fluid Dynamics · Physics 2015-08-07 Ken Yamamoto , Yuki Yamagata , Madoka Moriya , Reiko Kuriyama , Yohei Sato

We demonstrate a single-beam, standoff (>10m) coherent anti-Stokes Raman scattering spectroscopy (CARS) of various materials, including trace amounts of explosives and nitrate samples, under ambient light conditions. The multiplex…

Optics · Physics 2010-12-02 O. Katz , A. Natan , S. Rosenwaks , Y. Silberberg

We theoretically investigate a scheme in which backward coherent anti-Stokes Raman scattering (CARS) is significantly enhanced by using slow light. Specifically, we reduce the group velocity of the Stokes excitation pulse by introducing a…

Optics · Physics 2017-01-03 Li Gong , Haifeng Wang

We propose an elegant scheme towards phase locking of two independent degenerate coherent anti-Stokes Raman scattering (CARS) processes. The optical implementation involves a modified Mach-Zehnder interferometer that is utilized to transfer…

Optics · Physics 2008-12-25 Qun Zhang

The sensitivity of classical Raman spectroscopy methods, such as Coherent Anti-Stokes Raman spectroscopy (CARS) or Stimulated Raman spectroscopy (SRS), is ultimately limited by shot-noise from the stimulating fields. We present the complete…

Optics · Physics 2021-10-22 Yoad Michael , Leon Bello , Michael Rosenbluh , Avi Pe'er

Airborne contaminants, e.g., bacterial spores, are usually analyzed by time consuming microscopic, chemical and biological assays. Current research into real time laser spectroscopic detectors of such contaminants is based on e.g. resonant…

We use a Langevin approach to analyze the quantum noise in Coherent Anti-Stokes Raman Spectroscopy (CARS) in several experimental scenarios: with continuous wave input fields acting simultaneously and with fast sequential pulsed lasers…

Statistical Mechanics · Physics 2009-11-10 Kunal K. Das , G. S. Agarwal , Yu. M. Golubev , M. O. Scully

Far field radiation pattern under tight focusing condition is investigated in Coherent Anti-stokes Raman Scattering (CARS) microscopy both in the forward (F-CARS) and backward (E-CARS) directions. While we assume no refraction index…

Optics · Physics 2009-11-11 D. Gachet , N. Sandeau , H. Rigneault

We propose an all-fiber-generated dual-soliton pulses based scheme for the background-free detection of coherent anti-Stokes Raman spectroscopy under the spectral focusing mechanism. Due to the strong birefringence and high nonlinearity of…

Optics · Physics 2016-05-30 Kun Chen , Tao Wu , Haoyun Wei , Yan Li