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Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

We present an edge preserving and denoising filter for enhancing the features in images, which contain an ROI having a narrow spatial extent. Typical examples include angiograms, or ROI spatially distributed in multiple locations and…

Computer Vision and Pattern Recognition · Computer Science 2013-03-12 Joseph Suresh Paul , Joshin John Mathew , Souparnika Kandoth Naroth , Chandrasekar Kesavadas

We propose a modular framework for predicting cancer specific survival directly from whole slide pathology images (WSIs). The framework consists of four key stages designed to capture prognostic and morphological heterogeneity. First, a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Garima Jain , Pranav Jeevan , Amit Sethi

Deep-learning techniques have been used widely to alleviate the labour-intensive and time-consuming manual annotation required for pixel-level tissue characterization. Our previous study introduced an efficient single dynamic network -…

Image and Video Processing · Electrical Eng. & Systems 2023-05-25 Haoju Leng , Ruining Deng , Zuhayr Asad , R. Michael Womick , Haichun Yang , Lipeng Wan , Yuankai Huo

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Using deep learning models to diagnose cancer from histology data presents several challenges. Cancer grading and localization of regions of interest (ROIs) in these images normally relies on both image- and pixel-level labels, the latter…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Jérôme Rony , Soufiane Belharbi , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Precise segmentation of bladder walls and tumor regions is an essential step towards non-invasive identification of tumor stage and grade, which is critical for treatment decision and prognosis of patients with bladder cancer (BC). However,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Jose Dolz , Xiaopan Xu , Jerome Rony , Jing Yuan , Yang Liu , Eric Granger , Christian Desrosiers , Xi Zhang , Ismail Ben Ayed , Hongbing Lu

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsheng He , Xingyu Li

Motivation: High resolution 2D whole slide imaging provides rich information about the tissue structure. This information can be a lot richer if these 2D images can be stacked into a 3D tissue volume. A 3D analysis, however, requires…

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Region of Interest (ROI)-based image compression optimizes bit allocation by prioritizing ROI for higher-quality reconstruction. However, as the users (including human clients and downstream machine tasks) become more diverse, ROI-based…

Computer Vision and Pattern Recognition · Computer Science 2025-07-04 Jian Jin , Fanxin Xia , Feng Ding , Xinfeng Zhang , Meiqin Liu , Yao Zhao , Weisi Lin , Lili Meng

Multiple Instance Learning (MIL) has been widely applied in histopathology to classify Whole Slide Images (WSIs) with slide-level diagnoses. While the ground truth is established by expert pathologists, the slides can be difficult to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marie Arrivat , Rémy Peyret , Elsa Angelini , Pietro Gori

Transferring large volumes of high-resolution images during wind turbine inspections introduces a bottleneck in assessing and detecting severe defects. Efficient coding must preserve high fidelity in blade regions while aggressively…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Raül Pérez-Gonzalo , Andreas Espersen , Søren Forchhammer , Antonio Agudo

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

Cancer remains one of the leading causes of morbidity and mortality worldwide. Comprehensive datasets that combine histopathological images with genetic and survival data across various tumour sites are essential for advancing computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Craig Myles , In Hwa Um , Craig Marshall , David Harris-Birtill , David J. Harrison

Whole slide image (WSI) has been widely used to assist automated diagnosis under the deep learning fields. However, most previous works only discuss the SINGLE task setting which is not aligned with real clinical setting, where pathologists…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Weiqin Zhao , Shujun Wang , Maximus Yeung , Tianye Niu , Lequan Yu

Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in…

Image and Video Processing · Electrical Eng. & Systems 2019-02-20 Brendon Lutnick , Brandon Ginley , Darshana Govind , Sean D. McGarry , Peter S. LaViolette , Rabi Yacoub , Sanjay Jain , John E. Tomaszewski , Kuang-Yu Jen , Pinaki Sarder

Specific and effective breast cancer therapy relies on the accurate quantification of PD-L1 positivity in tumors, which appears in the form of brown stainings in high resolution whole slide images (WSIs). However, the retrieval and…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Giacomo Cignoni , Cristian Scatena , Chiara Frascarelli , Nicola Fusco , Antonio Giuseppe Naccarato , Giuseppe Nicoló Fanelli , Alina Sîrbu

Whole Slide Image (WSI) analysis, with its ability to reveal detailed tissue structures in magnified views, plays a crucial role in cancer diagnosis and prognosis. Due to their giga-sized nature, WSIs require substantial storage and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Doanh Cao Bui , Jin Tae Kwak