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Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Nanna E. Wielenberg , Ilinca Popp , Oliver Blanck , Lucas Zander , Jan C. Peeken , Stephanie E. Combs , Anca-Ligia Grosu , Dimos Baltas , Tobias Fechter

Accurate registration of brain MRI scans is fundamental for cross-subject analysis in neuroscientific studies. This involves aligning both the cortical surface of the brain and the interior volume. Traditional methods treat volumetric and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 S. Mazdak Abulnaga , Andrew Hoopes , Malte Hoffmann , Robin Magnet , Maks Ovsjanikov , Lilla Zöllei , John Guttag , Bruce Fischl , Adrian Dalca

Precise 3D segmentation of infant brain tissues is an essential step towards comprehensive volumetric studies and quantitative analysis of early brain developement. However, computing such segmentations is very challenging, especially for…

Computer Vision and Pattern Recognition · Computer Science 2017-12-20 Jose Dolz , Christian Desrosiers , Li Wang , Jing Yuan , Dinggang Shen , Ismail Ben Ayed

Deep learning approaches may help radiologists in the early diagnosis and timely treatment of cerebrovascular diseases. Accurate cerebral vessel segmentation of Time-of-Flight Magnetic Resonance Angiographs (TOF-MRAs) is an essential step…

Image and Video Processing · Electrical Eng. & Systems 2021-01-25 V. de Vos , K. M. Timmins , I. C. van der Schaaf , Y. Ruigrok , B. K. Velthuis , H. J. Kuijf

Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Haoran Dou , Davood Karimi , Caitlin K. Rollins , Cynthia M. Ortinau , Lana Vasung , Clemente Velasco-Annis , Abdelhakim Ouaalam , Xin Yang , Dong Ni , Ali Gholipour

Preterm infants (born between 28 and 37 weeks of gestation) face elevated risks of neurodevelopmental delays, making early identification crucial for timely intervention. While deep learning-based volumetric segmentation of brain MRI scans…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Lexin Ren , Jiamiao Lu , Weichuan Zhang , Benqing Wu , Tuo Wang , Yi Liao , Jiapan Guo , Changming Sun , Liang Guo

Fetal brain segmentation is an important first step for slice-level motion correction and slice-to-volume reconstruction in fetal MRI. Fast and accurate segmentation of the fetal brain on fetal MRI is required to achieve real-time fetal…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdogmus , Ali Gholipour

In obstetric ultrasound (US) scanning, the learner's ability to mentally build a three-dimensional (3D) map of the fetus from a two-dimensional (2D) US image represents a significant challenge in skill acquisition. We aim to build a US…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Chiara Di Vece , Maela Le Lous , Brian Dromey , Francisco Vasconcelos , Anna L David , Donald Peebles , Danail Stoyanov

Whole brain segmentation on a structural magnetic resonance imaging (MRI) is essential in non-invasive investigation for neuroanatomy. Historically, multi-atlas segmentation (MAS) has been regarded as the de facto standard method for whole…

Computer Vision and Pattern Recognition · Computer Science 2018-06-06 Yuankai Huo , Zhoubing Xu , Katherine Aboud , Prasanna Parvathaneni , Shunxing Bao , Camilo Bermudez , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

3D medical image processing with deep learning greatly suffers from a lack of data. Thus, studies carried out in this field are limited compared to works related to 2D natural image analysis, where very large datasets exist. As a result,…

Computer Vision and Pattern Recognition · Computer Science 2020-11-24 Hicham Messaoudi , Ahror Belaid , Mohamed Lamine Allaoui , Ahcene Zetout , Mohand Said Allili , Souhil Tliba , Douraied Ben Salem , Pierre-Henri Conze

Segmentation of magnetic resonance images (MRI) facilitates analysis of human brain development by delineating anatomical structures. However, in infants and young children, accurate segmentation is challenging due to development and…

Machine Learning · Computer Science 2026-04-01 Malte Hoffmann , Lilla Zöllei , Adrian V. Dalca

This paper presents DeepFLASH, a novel network with efficient training and inference for learning-based medical image registration. In contrast to existing approaches that learn spatial transformations from training data in the high…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Jian Wang , Miaomiao Zhang

Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Dennis Bontempi , Sergio Benini , Alberto Signoroni , Michele Svanera , Lars Muckli

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

Introduction: Fetal resting-state functional magnetic resonance imaging (rs-fMRI) is a rapidly evolving field that provides valuable insight into brain development before birth. Accurate segmentation of the fetal brain from the surrounding…

Purpose: Widening the availability of fetal MRI with fully automatic real-time planning of radiological brain planes on 0.55T MRI. Methods: Deep learning-based detection of key brain landmarks on a whole-uterus EPI scan enables the…

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, head segmentation is commonly used for measuring and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Haleh Akrami , Wenhui Cui , Anand A Joshi , Richard M. Leahy

The lack of a comprehensive high-resolution atlas of the cerebellum has hampered studies of cerebellar involvement in normal brain function and disease. A good representation of the tightly foliated aspect of the cerebellar cortex is…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Xuan Li , Paule-J Toussaint , Alan Evans , Xue Liu