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Due to the recent coronavirus outbreak, many efforts and innovative solutions have surfaced to deal with the possible shortage of ventilators upon catastrophic surges of patients. One solution involves splitting one ventilator to treat…

Mechanical ventilation is used for patients with a variety of lung diseases. Traditionally, ventilators have been designed to monotonously deliver equal sized breaths. While it may seem intuitive that lungs may benefit from unvarying and…

Quantitative Methods · Quantitative Biology 2015-09-18 Reena Yadav , Mayur Ghatge , Kirankumar Hiremath , Ganesh Bagler

Mechanical ventilators sustain life of patients that are unable to breathe (sufficiently) on their own. The aim of this paper is to improve pressure tracking performance of mechanical ventilators for a wide variety of sedated patients. This…

Systems and Control · Electrical Eng. & Systems 2020-04-02 Joey Reinders , Ruben Verkade , Bram Hunnekens , Nathan van de Wouw , Tom Oomen

Background: Mechanical ventilation is life-saving for preterm infants with respiratory distress syndrome but can also contribute to lung injury and long-term morbidity. Protective ventilation strategies are recommended, yet implementation…

Medical Physics · Physics 2025-09-24 Sina Saffaran , Tng Chang Kwok , Don Sharkey , Declan G. Bates

A variety of optimal control, estimation, system identification and design problems can be formulated as functional optimization problems with differential equality and inequality constraints. Since these problems are infinite-dimensional…

We show that enhanced turbulent mixing can be used to mitigate airborne COVID-19 transmission by dispersing virus-laden clouds in enclosed, poorly ventilated spaces. A simple system of fan-driven turbulent jets is designed so as to minimize…

Fluid Dynamics · Physics 2022-01-20 Justin Tahmassebpur , Patrick H. Diamond

We propose a synthesis method for the design of digital twins applicable to various systems (pneumatic, hydraulic, electrical/electronic circuits). The methodology allows representing the operation of these systems through an active digital…

Systems and Control · Electrical Eng. & Systems 2024-10-01 Veyis Gunes

Mechanical ventilation is one of the most widely used therapies in the ICU. However, despite broad application from anaesthesia to COVID-related life support, many injurious challenges remain. We frame these as a control problem:…

Smart devices, storage and other distributed technologies have the potential to greatly improve the utilisation of network infrastructure and renewable generation. Decentralised control of these technologies overcomes many scalability and…

Optimization and Control · Mathematics 2024-10-30 Paul Scott , Sylvie Thiébaux

Bubble curtains are widely used to protect marine life from exposure to noise during offshore construction. However, operating a bubble curtain is costly. Therefore optimizing the acoustic effect of the available air is important. An…

Fluid Dynamics · Physics 2024-10-21 Simon Beelen , Marten Nijhof , Christ de Jong , Leen van Wijngaarden , Dominik Krug

A novel scheme for tunable optofluidic optical coupler is proposed, by using directional coupling waveguide structure and microfluidic channel with two tapers at end points. The normalized optical power at two output ports can be…

Applied Physics · Physics 2019-10-01 Xionggui Tang , Fang Meng

This paper studies a scalable control method for multi-zone heating, ventilation and air-conditioning (HVAC) systems to optimize the energy cost for maintaining thermal comfort and indoor air quality (IAQ) (represented by CO2)…

Systems and Control · Electrical Eng. & Systems 2021-01-05 Yu Yang , Seshadhri Srinivasan , Guoqiang Hu , Costas J. Spanos

Pneumatic pressure cells with thin metallic spherical diaphragm of shallow spherical shell configuration linked with vibrating wire pickup or vibrating cantilever pickup were reported in the past. In order to enhance the sensitivity of the…

Systems and Control · Computer Science 2012-03-13 Akin Cellatoglu , Balasubramanian Karuppanan

Recently, Kami\'nski et al. [1] demonstrated that a two-dimensional streamwise waviness with carefully selected amplitude and period can be effectively used in postponement of a flow separation at high Reynolds number which is out of reach…

Fluid Dynamics · Physics 2025-05-29 Piotr Kamiński , Artur Tyliszczak , Witold Elsner , Paweł Niegodajew

Controlling the air quality is of the utmost importance in today buildings. Vertical air curtains are often used to separate two different climatic zones with a view to reduce heat transfer. In fact, this research work proposes an air…

Fluid Dynamics · Physics 2020-02-27 Joao Carlos Viegas , Fernando Oliveira , Daniel Aelenei

Pedestrian dynamics simulates the fine-scaled trajectories of individuals in a crowd. It has been used to suggest public health interventions to reduce infection risk in important components of air travel, such as during boarding and in…

Computers and Society · Computer Science 2024-10-21 Ashok Srinivasan , Satkkeerthi Sriram , Sirish Namilae , Andrew Arash Mahyari

This paper presents a recurrent neural network approach to simulating mechanical ventilator pressure. The traditional mechanical ventilator has a control pressure that is monitored by a medical practitioner and can behave incorrectly if the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-10 Su Diao , Changsong Wei , Junyu Wang , Yizhou Li

Cardiac digital twins are computational tools capturing key functional and anatomical characteristics of patient hearts for investigating disease phenotypes and predicting responses to therapy. When paired with large-scale computational…

Computational Engineering, Finance, and Science · Computer Science 2024-01-19 Julia Camps , Zhinuo Jenny Wang , Ruben Doste , Maxx Holmes , Brodie Lawson , Jakub Tomek , Kevin Burrage , Alfonso Bueno-Orovio , Blanca Rodriguez

This work presents an algorithm for determining the parameters of a nonlinear dynamic model of the respiratory system in patients undergoing assisted ventilation. Using the pressure and flow signals measured at the mouth, the model's…

Systems and Control · Electrical Eng. & Systems 2024-03-01 Diego A. Riva , Carolina A. Evangelista , Paul F. Puleston , Luis Corsiglia , Nahuel Dargains

We present a viable prototype of a simple mechanical ventilator intended as a last resort to ventilate COVID-19 patients. The prototype implements the pressure-controlled continuous mandatory ventilation mode (PC-CMV) with settable…

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