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Accurate diagnosis of pediatric brain tumors, starting with histopathology, presents unique challenges for deep learning, including severe data scarcity, class imbalance, and fine-grained morphologic overlap across diagnostically distinct…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Joakim Nguyen , Jian Yu , Jinrui Fang , Nicholas Konz , Tianlong Chen , Sanjay Krishnan , Chandra Krishnan , Ying Ding , Hairong Wang , Ankita Shukla

This paper presents a generative model for super-resolution in routine clinical magnetic resonance images (MRI), of arbitrary orientation and contrast. The model recasts the recovery of high resolution images as an inverse problem, in which…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Mikael Brudfors , Yael Balbastre , Parashkev Nachev , John Ashburner

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Sean Grullon , Vaughn Spurrier , Jiayi Zhao , Corey Chivers , Yang Jiang , Kiran Motaparthi , Michael Bonham , Julianna Ianni

Automatic segmentation of brain tumors is an essential but challenging step for extracting quantitative imaging biomarkers for accurate tumor detection, diagnosis, prognosis, treatment planning and assessment. Multimodal Brain Tumor…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Yading Yuan

Super-resolution (SR) for image enhancement has great importance in medical image applications. Broadly speaking, there are two types of SR, one requires multiple low resolution (LR) images from different views of the same object to be…

Image and Video Processing · Electrical Eng. & Systems 2018-10-17 Jin Zhu , Guang Yang , Pietro Lio

In this work, we tackle the problem of Semi-Supervised Anomaly Segmentation (SAS) in Magnetic Resonance Images (MRI) of the brain, which is the task of automatically identifying pathologies in brain images. Our work challenges the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Georgios Kaissis , Daniel Rueckert

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

The volume estimation of brain regions from MRI data is a key problem in many clinical applications, where the acquisition of data at high spatial resolution is desirable. While parallel MRI and constrained image reconstruction algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Aniket Pramanik , Xiaodong Wu , Mathews Jacob

Homologous anatomical landmarks between medical scans are instrumental in quantitative assessment of image registration quality in various clinical applications, such as MRI-ultrasound registration for tissue shift correction in…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Soorena Salari , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

The detection of new or enlarged white-matter lesions in multiple sclerosis is a vital task in the monitoring of patients undergoing disease-modifying treatment for multiple sclerosis. However, the definition of 'new or enlarged' is not…

Self-supervised learning has proven to be an effective way to learn representations in domains where annotated labels are scarce, such as medical imaging. A widely adopted framework for this purpose is contrastive learning and it has been…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Hugo Figueiras , Helena Aidos , Nuno Cruz Garcia

Brain activation mapping using functional MRI (fMRI) based on blood oxygenation level-dependent (BOLD) contrast has been conventionally focused on probing gray matter, the BOLD contrast in white matter having been generally disregarded.…

Signal Processing · Electrical Eng. & Systems 2019-10-25 David Abramian , Martin Larsson , Anders Eklund , Hamid Behjat

There are many clinical contexts which require accurate detection and segmentation of all focal pathologies (e.g. lesions, tumours) in patient images. In cases where there are a mix of small and large lesions, standard binary cross entropy…

Image and Video Processing · Electrical Eng. & Systems 2022-05-19 Brennan Nichyporuk , Justin Szeto , Douglas L. Arnold , Tal Arbel

Brain lesions, including stroke and tumours, have a high degree of variability in terms of location, size, intensity and form, making automatic segmentation difficult. We propose an improvement to existing segmentation methods by exploiting…

Image and Video Processing · Electrical Eng. & Systems 2019-07-22 Kevin Raina , Uladzimir Yahorau , Tanya Schmah

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

Whole brain segmentation on structural magnetic resonance imaging (MRI) is essential for understanding neuroanatomical-functional relationships. Traditionally, multi-atlas segmentation has been regarded as the standard method for whole…

Computer Vision and Pattern Recognition · Computer Science 2019-01-09 Yunxi Xiong , Yuankai Huo , Jiachen Wang , L. Taylor Davis , Maureen McHugo , Bennett A. Landman

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated modalities -- notably magnetic resonance (MR) imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Peirong Liu , Oula Puonti , Xiaoling Hu , Daniel C. Alexander , Juan E. Iglesias

Segmentation of brain structures in a large dataset of magnetic resonance images (MRI) necessitates automatic segmentation instead of manual tracing. Automatic segmentation methods provide a much-needed alternative to manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Mohammad-Parsa Hosseini , Esmaeil Davoodi , Evangelia Bouzos , Kost Elisevich , Hamid Soltanian-Zadeh

Whole brain segmentation and cortical surface parcellation are essential in understanding the anatomical-functional relationships of the brain. Multi-atlas segmentation has been regarded as one of the leading segmentation methods for the…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Yuankai Huo , Shunxing Bao , Prasanna Parvathaneni , Bennett A. Landman
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