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Current mathematical frameworks for predicting the flux state and macromolecular composition of the cell do not rely on thermodynamic constraints to determine the spontaneous direction of reactions. These predictions may be biologically…

Optimization and Control · Mathematics 2020-08-14 Amir Akbari , Bernhard O. Palsson

This paper shows that the optimal policy and value functions of a Markov Decision Process (MDP), either discounted or not, can be captured by a finite-horizon undiscounted Optimal Control Problem (OCP), even if based on an inexact model.…

Systems and Control · Electrical Eng. & Systems 2023-02-08 Arash Bahari Kordabad , Mario Zanon , Sebastien Gros

Axiomatic approach has demonstrated its power in mathematics. The main goal of this preprint is to show that axiomatic methods are also very efficient for computer science. It is possible to apply these methods to many problems in computer…

Logic · Mathematics 2007-05-23 Mark Burgin

Quantitative logic reasons about the degree to which formulas are satisfied. This paper studies the fundamental reasoning principles of higher-order quantitative logic and their application to reasoning about probabilistic programs and…

Logic in Computer Science · Computer Science 2026-05-21 Giorgio Bacci , Rasmus Ejlers Møgelberg

The process of calibrating computer models of natural phenomena is essential for applications in the physical sciences, where plenty of domain knowledge can be embedded into simulations and then calibrated against real observations. Current…

Machine Learning · Computer Science 2025-01-20 Rafael Oliveira , Dino Sejdinovic , David Howard , Edwin V. Bonilla

We resolve the fundamental problem of online decoding with general $n^{th}$ order ergodic Markov chain models. Specifically, we provide deterministic and randomized algorithms whose performance is close to that of the optimal offline…

Machine Learning · Computer Science 2019-05-31 Vikas K. Garg , Tamar Pichkhadze

The ultimate goal of a supervised learning algorithm is to produce models constructed on the training data that can generalize well to new examples. In classification, functional margin maximization -- correctly classifying as many training…

Machine Learning · Computer Science 2020-01-29 Nikolaos Nikolaou , Henry Reeve , Gavin Brown

Ordinary differential equations obtained as limits of Markov processes appear in many settings. They may arise by scaling large systems, or by averaging rapidly fluctuating systems, or in systems involving multiple time-scales, by a…

Probability · Mathematics 2014-03-24 Hye-Won Kang , Thomas G. Kurtz , Lea Popovic

We construct a general procedure for the Quasi Likelihood Analysis applied to a multivariate point process on the real half line in an ergodic framework. More precisely, we assume that the stochastic intensity of the underlying model…

Statistics Theory · Mathematics 2016-09-28 Simon Clinet , Nakahiro Yoshida

Machines that can replicate human intelligence with type 2 reasoning capabilities should be able to reason at multiple levels of spatio-temporal abstractions and scales using internal world models. Devising formalisms to develop such…

Artificial Intelligence · Computer Science 2025-07-01 Vaisakh Shaj

An important question in the field of AI is the extent to which successful behaviour requires an internal representation of the world. In this work, we quantify the amount of information an optimal policy provides about the underlying…

Artificial Intelligence · Computer Science 2026-02-16 Alfred Harwood , Jose Faustino , Alex Altair

The past century has seen a steady increase in the need of estimating and predicting complex systems and making (possibly critical) decisions with limited information. Although computers have made possible the numerical evaluation of…

Statistics Theory · Mathematics 2017-01-13 Houman Owhadi , Clint Scovel

Markov decision processes (MDPs) is viewed as an optimization of an objective function over certain linear operators over general function spaces. A new existence result is established for the existence of optimal policies in general MDPs,…

Machine Learning · Computer Science 2026-04-01 Abhishek Gupta , Aditya Mahajan

We propose that unconstrained artificial intelligence obeys a Second Law analogous to thermodynamics, where ethical entropy, defined as a measure of divergence from intended goals, increases spontaneously without continuous alignment work.…

Artificial Intelligence · Computer Science 2025-11-19 Samih Fadli

As we know, some global optimization problems cannot be solved using analytic methods, so numeric/algorithmic approaches are used to find near to the optimal solutions for them. A stochastic global optimization algorithm (SGoal) is an…

Artificial Intelligence · Computer Science 2017-06-08 Jonatan Gomez

I consider motivation and value-alignment in AI systems from the perspective of (constrained) entropy maximization. Though the structures encoding knowledge in any physical system can be understood as energetic constraints, only living…

Neurons and Cognition · Quantitative Biology 2025-08-29 Alex B. Kiefer

We propose a neural network approach to model general interaction dynamics and an adjoint based stochastic gradient descent algorithm to calibrate its parameters. The parameter calibration problem is considered as optimal control problem…

Optimization and Control · Mathematics 2021-02-01 Simone Göttlich , Claudia Totzeck

Decision-theoretic planning with risk-sensitive planning objectives is important for building autonomous agents or decision-support systems for real-world applications. However, this line of research has been largely ignored in the…

Artificial Intelligence · Computer Science 2012-07-09 Yaxin Liu , Sven Koenig

We derive a thermodynamic uncertainty relation for general open quantum dynamics, described by a joint unitary evolution on a composite system comprising a system and an environment. By measuring the environmental state after the…

Statistical Mechanics · Physics 2021-01-06 Yoshihiko Hasegawa

Operational quantum stochastic thermodynamics is a recently proposed theory to study the thermodynamics of open systems based on the rigorous notion of a quantum stochastic process or quantum causal model. In there, a stochastic trajectory…

Quantum Physics · Physics 2020-03-04 Philipp Strasberg
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