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Previous work has examined how debiasing language models affect downstream tasks, specifically, how debiasing techniques influence task performance and whether debiased models also make impartial predictions in downstream tasks or not.…

Computation and Language · Computer Science 2022-06-03 Sullam Jeoung , Jana Diesner

Probabilities of causation (PoC) offer valuable insights for informed decision-making. This paper introduces novel variants of PoC-controlled direct, natural direct, and natural indirect probability of necessity and sufficiency (PNS). These…

Artificial Intelligence · Computer Science 2024-12-20 Yuta Kawakami , Jin Tian

Clinical decisions to treat and diagnose patients are affected by implicit biases formed by racism, ableism, sexism, and other stereotypes. These biases reflect broader systemic discrimination in healthcare and risk marginalizing already…

Machine Learning · Computer Science 2025-01-29 Kara Liu , Russ Altman , Vasilis Syrgkanis

Relationships of cause and effect are of prime importance for explaining scientific phenomena. Often, rather than just understanding the effects of causes, researchers also wish to understand how a cause $X$ affects an outcome $Y$…

Methodology · Statistics 2024-11-14 Drago Plecko

Not accounting for competing events in survival analysis can lead to biased estimates, as individuals who die from other causes do not have the opportunity to develop the event of interest. Formal definitions and considerations for causal…

When it comes to clinical survival trials, regulatory restrictions usually require the application of methods that solely utilize baseline covariates and the intention-to-treat principle. Thereby a lot of potentially useful information is…

We propose a difference-in-differences (DiD) framework with mediation for possibly multivalued discrete or continuous treatments and mediators, aimed at identifying the direct effect of the treatment on the outcome (net of effects operating…

Econometrics · Economics 2026-03-02 Martin Huber , Sarina Joy Oberhänsli

Mediation analysis has been widely used to investigate how a treatment influences an outcome through intermediate variables, known as mediators. Analyzing a mediation mechanism typically requires assessing multiple model parameters that…

Methodology · Statistics 2025-10-01 Hanying Jiang , Kris Sankaran , Yinqiu He

Two of the most important extensions of the basic regression model are moderated effects (due to interactions) and mediated effects (i.e. indirect effects). Combinations of these effects may also be present. In this work, an important, yet…

Methodology · Statistics 2022-08-17 Geert H. van Kollenburg , Marcel A. Croon

In this paper new tests for the independence of two high-dimensional vectors are investigated. We consider the case where the dimension of the vectors increases with the sample size and propose multivariate analysis of variance-type…

Statistics Theory · Mathematics 2023-04-19 Taras Bodnar , Holger Dette , Nestor Parolya

Researchers have focused on understanding how individual's behavior is influenced by the behaviors of their peers in observational studies of social networks. Identifying and estimating causal peer influence, however, is challenging due to…

Applications · Statistics 2024-06-18 Seungha Um , Tracy Sweet , Samrachana Adhikari

This paper develops methods for estimating the natural direct and indirect effects in causal mediation analysis. The efficient influence function-based estimator (EIF-based estimator) and the inverse probability weighting estimator (IPW…

Methodology · Statistics 2025-12-11 Kentaro Kawato

Unscheduled treatment interruptions may lead to reduced quality of care in radiation therapy (RT). Identifying the RT prescription dose effects on the outcome of treatment interruptions, mediated through doses distributed into different…

Methodology · Statistics 2024-09-25 Zijin Liu , Zhihui Liu , Ali Hosni , John Kim , Bei Jiang , Olli Saarela

Mediation analysis is an important tool for studying causal associations in biomedical and other scientific areas and has recently gained attention in microbiome studies. Using a microbiome study of acute myeloid leukemia (AML) patients, we…

Network interference occurs when treatments assigned to some units affect the outcomes of others. Traditional approaches often assume that the observed network correctly specifies the interference structure. However, in practice,…

Methodology · Statistics 2026-02-04 Bar Weinstein , Daniel Nevo

Large-scale black-box models have become ubiquitous across numerous applications. Understanding the influence of individual training data sources on predictions made by these models is crucial for improving their trustworthiness. Current…

Machine Learning · Computer Science 2024-06-21 Myeongseob Ko , Feiyang Kang , Weiyan Shi , Ming Jin , Zhou Yu , Ruoxi Jia

Influence function (IF)-based estimators are widely used in mediation analysis due to their modeling flexibility, but standard implementations require direct estimation of the distribution functions of the mediator and treatment variables.…

Methodology · Statistics 2026-02-10 Chang Liu , AmirEmad Ghassami

Motivated by an analysis of causal mechanism from economic stress to entrepreneurial withdrawals through depressed affect, we develop a two-layer generalized varying coefficient mediation model. This model captures the bridging effects of…

Statistics Theory · Mathematics 2022-12-06 Jingyuan Liu , Yujie Liao , Runze Li

Environmental health studies are increasingly measuring endogenous omics data ($\boldsymbol{M}$) to study intermediary biological pathways by which an exogenous exposure ($\boldsymbol{A}$) affects a health outcome ($\boldsymbol{Y}$), given…

How should researchers conduct causal inference when the outcome of interest is latent and measured imperfectly by multiple indicators? We develop a general nonparametric framework for identifying and estimating average treatment effects on…

Methodology · Statistics 2026-04-22 Jiawei Fu , Donald P. Green