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Related papers: Evidence Inference 2.0: More Data, Better Models

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The best evidence concerning comparative treatment effectiveness comes from clinical trials, the results of which are reported in unstructured articles. Medical experts must manually extract information from articles to inform…

Computation and Language · Computer Science 2022-01-11 Benjamin E. Nye , Jay DeYoung , Eric Lehman , Ani Nenkova , Iain J. Marshall , Byron C. Wallace

How do we know if a particular medical treatment actually works? Ideally one would consult all available evidence from relevant clinical trials. Unfortunately, such results are primarily disseminated in natural language scientific articles,…

Computation and Language · Computer Science 2019-04-08 Eric Lehman , Jay DeYoung , Regina Barzilay , Byron C. Wallace

Systematic use of the published results of randomized clinical trials is increasingly important in evidence-based medicine. In order to collate and analyze the results from potentially numerous trials, evidence tables are used to represent…

Computation and Language · Computer Science 2015-09-18 Antonio Trenta , Anthony Hunter , Sebastian Riedel

Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions. Due to the sheer volume and rapid growth of medical literature and the high…

Computation and Language · Computer Science 2025-05-29 Zihan Xu , Haotian Ma , Gongbo Zhang , Yihao Ding , Chunhua Weng , Yifan Peng

With the rapid development of precision medicine, a large amount of health data (such as electronic health records, gene sequencing, medical images, etc.) has been produced. It encourages more and more interest in data-driven insight…

Computation and Language · Computer Science 2019-12-10 Sendong Zhao , Fei Wang

Evidence-based medicine is the practice of making medical decisions that adhere to the latest, and best known evidence at that time. Currently, the best evidence is often found in the form of documents, such as randomized control trials,…

Computation and Language · Computer Science 2024-05-21 Anthony Hughes , Xingyi Song

Biomedical knowledge resources often either preserve evidence as unstructured text or compress it into flat triples that omit study design, provenance, and quantitative support. Here we present EvidenceNet, a disease-specific dataset of…

Computational Engineering, Finance, and Science · Computer Science 2026-04-15 Chang Zong , Sicheng Lv , Si-tu Xue , Huilin Zheng , Jian Wan , Lei Zhang

How can we interpret and retrieve medical evidence to support clinical decisions? Clinical trial reports (CTR) amassed over the years contain indispensable information for the development of personalized medicine. However, it is practically…

Computation and Language · Computer Science 2023-10-31 Maël Jullien , Marco Valentino , Hannah Frost , Paul O'Regan , Donal Landers , André Freitas

We study the task of automatically finding evidence relevant to hypotheses in biomedical papers. Finding relevant evidence is an important step when researchers investigate scientific hypotheses. We introduce EvidenceBench to measure models…

This article emphasizes that NLP as a science seeks to make inferences about the performance effects that result from applying one method (compared to another method) in the processing of natural language. Yet NLP research in practice…

Computation and Language · Computer Science 2022-09-15 Sandra Wankmüller

A simple and common type of medical research involves the comparison of one treatment against another. The logical aim should be both to establish which treatment is superior and the strength of evidence supporting this conclusion, a task…

Methodology · Statistics 2022-12-08 Nicholas Adams

Concerns over reproducibility in science extend to research using existing healthcare data; many observational studies investigating the same topic produce conflicting results, even when using the same data. To address this problem, we…

Applications · Statistics 2018-03-30 Martijn J. Schuemie , Patrick B. Ryan , George Hripcsak , David Madigan , Marc A. Suchard

A data science task can be deemed as making sense of the data or testing a hypothesis about it. The conclusions inferred from data can greatly guide us to make informative decisions. Big data has enabled us to carry out countless prediction…

Machine Learning · Computer Science 2022-01-12 Wenhao Zhang , Ramin Ramezani , Arash Naeim

When addressing professional questions in the biomedical domain, humans typically acquire multiple pieces of information as evidence and engage in multifaceted analysis to provide high-quality answers. Current LLM-based question answering…

Computation and Language · Computer Science 2025-09-03 Chang Zong , Jian Wan , Siliang Tang , Lei Zhang

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Systematic reviews in medicine play a critical role in evidence-based decision-making by aggregating findings from multiple studies. A central bottleneck in automating this process is extracting numeric evidence and determining study-level…

Artificial Intelligence · Computer Science 2026-01-26 Massimiliano Pronesti , Michela Lorandi , Paul Flanagan , Oisin Redmond , Anya Belz , Yufang Hou

To assess the effectiveness of any medical intervention, researchers must conduct a time-intensive and highly manual literature review. NLP systems can help to automate or assist in parts of this expensive process. In support of this goal,…

Computation and Language · Computer Science 2021-11-24 Jay DeYoung , Iz Beltagy , Madeleine van Zuylen , Bailey Kuehl , Lucy Lu Wang

Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…

Human-Computer Interaction · Computer Science 2017-07-10 Gaurav Trivedi , Phuong Pham , Wendy Chapman , Rebecca Hwa , Janyce Wiebe , Harry Hochheiser

Clinical evidence encompasses the associations and impacts between patients, interventions (such as drugs or physiotherapy), problems, and outcomes. The goal of recommending clinical evidence is to provide medical practitioners with…

Computation and Language · Computer Science 2023-04-05 Maolin Luo , Xiang Zhang

Combination therapies have become the standard of care for diseases such as cancer, tuberculosis, malaria and HIV. However, the combinatorial set of available multi-drug treatments creates a challenge in identifying effective combination…

Computation and Language · Computer Science 2022-05-06 Aryeh Tiktinsky , Vijay Viswanathan , Danna Niezni , Dana Meron Azagury , Yosi Shamay , Hillel Taub-Tabib , Tom Hope , Yoav Goldberg
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