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SARS-CoV-2 is a new human coronavirus (CoV), which emerged in China in late 2019 and is responsible for the global COVID-19 pandemic that caused more than 59 million infections and 1.4 million deaths in 11 months. Understanding the origin…

Populations and Evolution · Quantitative Biology 2020-11-26 Erwan Sallard , José Halloy , Didier Casane , Etienne Decroly , Jacques van Helden

Antibodies are crucial proteins produced by the immune system to eliminate harmful foreign substances and have become pivotal therapeutic agents for treating human diseases. To accelerate the discovery of antibody therapeutics, there is…

Machine Learning · Computer Science 2024-10-17 Hirofumi Tsuruta , Hiroyuki Yamazaki , Ryota Maeda , Ryotaro Tamura , Akihiro Imura

The Corona Virus Disease 2019 (COVID-19) belongs to human coronaviruses (HCoVs), which spreads rapidly around the world. Compared with new drug development, drug repurposing may be the best shortcut for treating COVID-19. Therefore, we…

Machine Learning · Computer Science 2021-07-21 Shuting Jin , Xiangxiang Zeng , Wei Huang , Feng Xia , Changzhi Jiang , Xiangrong Liu , Shaoliang Peng

Coronavirus disease 2019 (COVID-19) is a continuously devastating public health and the world economy. One of the major challenges in controlling the COVID-19 outbreak is its asymptomatic infection and transmission, which are elusive and…

Populations and Evolution · Quantitative Biology 2020-07-06 Rui Wang , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus caused the novel coronavirus disease-2019 (COVID-19) affecting the whole world. Like SARS-CoV and MERS-CoV, SARS-CoV-2 are thought to originate in bats and then spread to…

Other Quantitative Biology · Quantitative Biology 2020-09-22 Daniel H. Tao , Weitao Sun

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected near 5 million people and led to over 0.3 million deaths. Currently, there is no specific anti-SARS-CoV-2…

Biomolecules · Quantitative Biology 2020-05-21 Kaifu Gao , Duc Duy Nguyen , Jiahui Chen , Rui Wang , Guo-Wei Wei

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the current global COVID-19 pandemic, in which millions of lives have been lost. Understanding the zoonotic evolution of the coronavirus may provide…

Populations and Evolution · Quantitative Biology 2022-01-04 Changchuan Yin

Understanding the spread of SARS-CoV-2 has been one of the most pressing problems of the recent past. Network models present a potent approach to studying such spreading phenomena because of their ability to represent complex social…

Social and Information Networks · Computer Science 2023-11-01 Christine Hedde-von Westernhagen , Javier Garcia-Bernardo , Ayoub Bagheri

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) has posed a serious threat to global health. As no specific therapeutics are yet available to control disease evolution, more in-depth…

Viral infections are causing significant morbidity and mortality worldwide. Understanding the interaction patterns between a particular virus and human proteins plays a crucial role in unveiling the underlying mechanism of viral infection…

Machine Learning · Computer Science 2021-11-30 Thi Ngan Dong , Graham Brogden , Gisa Gerold , Megha Khosla

A new coronavirus identified as SARS-CoV-2 virus has brought the world to a state of crisis, causing a major pandemic, claiming more than 433,000 lives and instigating major financial damage to the global economy. Despite current efforts,…

Biomolecules · Quantitative Biology 2020-06-18 Mohsen Chitsaz

Coronavirus disease (COVID-19) which is caused by SARS-COV2 has become a pandemic. This disease is highly infectious and potentially fatal, causing a global public health concern. To contain the spread of COVID-19, governments are adopting…

Physics and Society · Physics 2020-06-22 Sayantari Ghosh , Saumik Bhattacharya

The COVID-19 pandemic, caused by SARS-CoV-2, highlighted the critical need for accurate prediction of disease severity to optimize healthcare resource allocation and patient management. The spike protein, which facilitates viral entry into…

Machine Learning · Computer Science 2025-06-02 Caio Cheohen , Vinnícius M. S. Gomes , Manuela L. da Silva

SARS-CoV-2, also known as COVID-19 or Coronavirus, is a viral contagious disease that is infected by a novel coronavirus, and has been rapidly spreading across the globe. It is very important to test and isolate people to reduce spread, and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Prerak Mann , Sahaj Jain , Saurabh Mittal , Aruna Bhat

After the detection of coronavirus disease 2019 (Covid-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, Hubei Province, China in late December, the cases of Covid-19 have spiralled out around the…

Populations and Evolution · Quantitative Biology 2022-10-12 Suman Bhowmick , Igor M. Sokolov , Hartmut H. K. Lentz

The novel Coronavirus Disease 2019 (COVID-19) is a global pandemic disease spreading rapidly around the world. A robust and automatic early recognition of COVID-19, via auxiliary computer-aided diagnostic tools, is essential for disease…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Md. Kamrul Hasan , Md. Ashraful Alam , Md. Toufick E Elahi , Shidhartho Roy , Sifat Redwan Wahid

There have been more than 850,000 confirmed cases and over 48,000 deaths from the human coronavirus disease 2019 (COVID-19) pandemic, caused by novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), in the United States alone.…

Quantitative Methods · Quantitative Biology 2020-05-25 Xiangxiang Zeng , Xiang Song , Tengfei Ma , Xiaoqin Pan , Yadi Zhou , Yuan Hou , Zheng Zhang , George Karypis , Feixiong Cheng

Researchers across the globe are seeking to rapidly repurpose existing drugs or discover new drugs to counter the the novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One promising…

The recent outbreak of a novel coronavirus (2019-nCoV) has quickly evolved into a global health crisis. The transmission potential of 2019-nCoV has been modelled and studied in several recent research works. The key factors such as the…

Populations and Evolution · Quantitative Biology 2020-02-11 Jun Li

The virus SARS-COV-2 caused disease COVID-19 has been declared a pandemic by WHO. Currently, over 210 countries and territories have been affected. Careful, well-designed drugs and vaccine for the total elimination of this virus seem to be…

Populations and Evolution · Quantitative Biology 2020-10-07 Bishal Chhetri , D. K. K. Vamsi , Vijay M. Bhagat , Ananth V. S. , Bhanu Prakash , Roshan Mandale , Swapna Muthusamy , Carani B Sanjeevi