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Molecular profiling data (e.g., gene expression) has been used for clinical risk prediction and biomarker discovery. However, it is necessary to integrate other prior knowledge like biological pathways or gene interaction networks to…

Genomics · Quantitative Biology 2016-09-22 Wenwen Min , Juan Liu , Shihua Zhang

High-dimensional data sets have become ubiquitous in the past few decades, often with many more covariates than observations. In the frequentist setting, penalized likelihood methods are the most popular approach for variable selection and…

Methodology · Statistics 2021-12-14 Ray Bai , Veronika Rockova , Edward I. George

Variable selection in linear models plays a pivotal role in modern statistics. Hard-thresholding methods such as $l_0$ regularization are theoretically ideal but computationally infeasible. In this paper, we propose a new approach, called…

Machine Learning · Statistics 2015-03-20 Kun Yang

This paper is a survey of dictionary screening for the lasso problem. The lasso problem seeks a sparse linear combination of the columns of a dictionary to best match a given target vector. This sparse representation has proven useful in a…

Machine Learning · Computer Science 2016-08-23 Zhen James Xiang , Yun Wang , Peter J. Ramadge

Neural networks are very successful tools in for example advanced classification. From a statistical point of view, fitting a neural network may be seen as a kind of regression, where we seek a function from the input space to a space of…

Machine Learning · Statistics 2021-07-06 Anton Johansson , Niklas Engsner , Claes Strannegård , Petter Mostad

Recently, new methods for model assessment, based on subsampling and posterior approximations, have been proposed for scaling leave-one-out cross-validation (LOO) to large datasets. Although these methods work well for estimating predictive…

Methodology · Statistics 2020-08-12 Måns Magnusson , Michael Riis Andersen , Johan Jonasson , Aki Vehtari

Label smoothing (LS) is a popular regularisation method for training neural networks as it is effective in improving test accuracy and is simple to implement. ``Hard'' one-hot labels are ``smoothed'' by uniformly distributing probability…

Machine Learning · Computer Science 2025-02-21 Guoxuan Xia , Olivier Laurent , Gianni Franchi , Christos-Savvas Bouganis

Recurrent neural networks (RNNs) have recently achieved remarkable successes in a number of applications. However, the huge sizes and computational burden of these models make it difficult for their deployment on edge devices. A practically…

Machine Learning · Computer Science 2019-12-10 Liangjian Wen , Xuanyang Zhang , Haoli Bai , Zenglin Xu

We consider the problem of fitting the parameters of a high-dimensional linear regression model. In the regime where the number of parameters $p$ is comparable to or exceeds the sample size $n$, a successful approach uses an…

Statistics Theory · Mathematics 2013-11-04 Adel Javanmard , Andrea Montanari

We present a suite of packages in R, Python, Julia, and C++ that efficiently solve the Sorted L-One Penalized Estimation (SLOPE) problem. The packages feature a highly efficient hybrid coordinate descent algorithm that fits generalized…

Computation · Statistics 2025-11-18 Johan Larsson , Malgorzata Bogdan , Krystyna Grzesiak , Mathurin Massias , Jonas Wallin

The growing prevalence of large language models (LLMs) and vision-language models (VLMs) has heightened the need for reliable techniques to determine whether a model has been fine-tuned from or is even identical to another. Existing…

Machine Learning · Computer Science 2025-09-30 Ruibo Chen , Sheng Zhang , Yihan Wu , Tong Zheng , Peihua Mai , Heng Huang

This thesis studies two problems in modern statistics. First, we study selective inference, or inference for hypothesis that are chosen after looking at the data. The motiving application is inference for regression coefficients selected by…

Machine Learning · Statistics 2015-07-02 Jason D. Lee

Recent research has focused on $\ell_1$ penalized least squares (Lasso) estimators for high-dimensional linear regressions in which the number of covariates $p$ is considerably larger than the sample size $n$. However, few studies have…

Statistics Theory · Mathematics 2022-05-05 Yuefeng Han , Ruey S. Tsay

The Lasso is an attractive technique for regularization and variable selection for high-dimensional data, where the number of predictor variables $p_n$ is potentially much larger than the number of samples $n$. However, it was recently…

Statistics Theory · Mathematics 2009-03-02 Nicolai Meinshausen , Bin Yu

To conduct regression analysis for data contaminated with outliers, many approaches have been proposed for simultaneous outlier detection and robust regression, so is the approach proposed in this manuscript. This new approach is called…

Methodology · Statistics 2016-03-25 Xiaoli Gao , Yixin Fang

Scoring rules are used to evaluate the quality of predictions that take the form of probability distributions. A scoring rule is strictly proper if its expected value is uniquely minimized by the true probability distribution. One of the…

Methodology · Statistics 2021-04-05 Zoe Guan

Classification rules can be severely affected by the presence of disturbing observations in the training sample. Looking for an optimal classifier with such data may lead to unnecessarily complex rules. So, simpler effective classification…

Statistics Theory · Mathematics 2017-01-19 Marina Antolín , Eustasio Del Barrio , Jean-Michel Loubes

Variance estimation in the linear model when $p > n$ is a difficult problem. Standard least squares estimation techniques do not apply. Several variance estimators have been proposed in the literature, all with accompanying asymptotic…

Methodology · Statistics 2014-01-30 Stephen Reid , Robert Tibshirani , Jerome Friedman

Regression with the lasso penalty is a popular tool for performing dimension reduction when the number of covariates is large. In many applications of the lasso, like in genomics, covariates are subject to measurement error. We study the…

Methodology · Statistics 2017-01-04 Øystein Sørensen , Arnoldo Frigessi , Magne Thoresen

This paper provides a statistical analysis of high-dimensional batch Reinforcement Learning (RL) using sparse linear function approximation. When there is a large number of candidate features, our result sheds light on the fact that…

Machine Learning · Computer Science 2020-11-10 Botao Hao , Yaqi Duan , Tor Lattimore , Csaba Szepesvári , Mengdi Wang
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