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Purpose: To assess whether a generative adversarial network (GAN) could synthesize realistic optical coherence tomography (OCT) images that satisfactorily serve as the educational images for retinal specialists and the training datasets for…

Medical Physics · Physics 2020-06-02 Ce Zheng , Xiaolin Xie , Kang Zhou , Bang Chen , Jili Chen , Haiyun Ye , Wen Li , Tong Qiao , Shenghua Gao , Jianlong Yang , Jiang Liu

Precis: A hybrid deep-learning model combines NFL reflectance and other OCT parameters to improve glaucoma diagnosis. Objective: To investigate if a deep learning model could be used to combine nerve fiber layer (NFL) reflectance and other…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Ou Tan , David S. Greenfield , Brian A. Francis , Rohit Varma , Joel S. Schuman , David Huang , Dongseok Choi

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-11-03 Aized Amin Soofi , Fazal-e-Amin

Ischemic stroke is a time-critical medical emergency where rapid diagnosis is essential for improving patient outcomes. Non-contrast computed tomography (NCCT) serves as the frontline imaging tool, yet it often fails to reveal the subtle…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Maria Thoma , Michalis A. Savelonas , Dimitris K. Iakovidis

With the advancement of deep learning techniques, an increasing number of methods have been proposed for optic disc and cup (OD/OC) segmentation from the fundus images. Clinically, OD/OC segmentation is often annotated by multiple clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Junde Wu , Huihui Fang , Dalu Yang , Zhaowei Wang , Wenshuo Zhou , Fangxin Shang , Yehui Yang , Yanwu Xu

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Jiaxuan Li , Peiyao Jin , Jianfeng Zhu , Haidong Zou , Xun Xu , Min Tang , Minwen Zhou , Yu Gan , Jiangnan He , Yuye Ling , Yikai Su

In this paper we present algorithms to diagnosis Pathological Myopia (PM) and detection of retinal structures and lesions such asOptic Disc (OD), Fovea, Atrophy and Detachment. All these tasks were performed in fundus imaging from PM…

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-24 Cheng Huang , Weizheng Xie , Tsengdar Lee , Karanjit Kooner , Ning Zhang , Jia Zhang

Glaucoma is one of the leading causes of vision impairment. Digital imaging techniques, such as color fundus photography (CFP) and optical coherence tomography (OCT), provide quantitative and noninvasive methods for glaucoma diagnosis.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Zhiyuan Yang , Bo Zhang , Yufei Shi , Ningze Zhong , Johnathan Loh , Huihui Fang , Yanwu Xu , Si Yong Yeo

Purpose: To evaluate nerve fiber layer (NFL) reflectance for glaucoma diagnosis using a large dataset. Methods: Participants were imaged with 4.9mm ONH scans using spectral-domain optical coherence tomography (OCT). The NFL reflectance map…

For optical coherence tomography angiography (OCTA) images, a limited scanning rate leads to a trade-off between field-of-view (FOV) and imaging resolution. Although larger FOV images may reveal more parafoveal vascular lesions, their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Weiwen Zhang , Dawei Yang , Haoxuan Che , An Ran Ran , Carol Y. Cheung , Hao Chen

Glaucoma is a disease in which the optic nerve is chronically damaged by the elevation of the intra-ocular pressure, resulting in visual field defect. Therefore, it is important to monitor and treat suspected patients before they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-05 Tae Joon Jun , Dohyeun Kim , Hoang Minh Nguyen , Daeyoung Kim , Youngsub Eom

High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…

Medical Physics · Physics 2020-07-31 Viacheslav Mazlin , Kristina Irsch , Michel Paques , Mathias Fink , Albert Claude Boccara

A resolution enhancement technique for optical coherence tomography (OCT), based on Generative Adversarial Networks (GANs), was developed and investigated. GANs have been previously used for resolution enhancement of photography and optical…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Kaicheng Liang , Xinyu Liu , Si Chen , Jun Xie , Wei Qing Lee , Linbo Liu , Hwee Kuan Lee

This investigation reports on the results of convolutional neural networks developed for the recently introduced PathologicAL Myopia (PALM) dataset, which consists of 1200 fundus images. We propose a new Optic Nerve Head (ONH)-based…

Image and Video Processing · Electrical Eng. & Systems 2020-06-05 Ruben Hemelings , Bart Elen , Matthew B. Blaschko , Julie Jacob , Ingeborg Stalmans , Patrick De Boever

Optical Character Recognition has been a challenging field in the advent of digital computers. It is needed where information is to be readable both to humans and machines. The process of OCR is composed of a set of pre and post processing…

Computer Vision and Pattern Recognition · Computer Science 2018-01-04 Chinmay Chinara , Nishant Nath , Subhajeet Mishra , Sangram Keshari Sahoo , Farida Ashraf Ali

Computational cytology faces two major challenges: i) instance-level labels are unreliable and prohibitively costly to obtain, ii) witness rates are extremely low. We propose SLAM-AGS, a Slide-Label-Aware Multitask pretraining framework…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Marco Acerbis , Swarnadip Chatterjee , Christophe Avenel , Joakim Lindblad

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan