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Related papers: Computational neurology: Computational modeling ap…

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Computational biomechanics of the brain for neurosurgery is an emerging area of research recently gaining in importance and practical applications. This review paper presents the contributions of the Intelligent Systems for Medicine…

Computational Engineering, Finance, and Science · Computer Science 2019-04-03 K. Miller , G. R. Joldes , G. Bourantas , S. K. Warfield , D. E. Hyde , R. Kikinis , A. Wittek

Studying psychiatric illness has often been limited by difficulties in connecting symptoms and behavior to neurobiology. Computational psychiatry approaches promise to bridge this gap by providing formal accounts of the latent information…

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the accumulation of amyloid-beta (A$\beta$) and phosphorylated tau (p-tau) proteins, leading to cognitive decline measured by the Alzheimer's Disease…

Neurons and Cognition · Quantitative Biology 2025-04-21 Swadesh Pal , Roderick Melnik

Computational modeling helps neuroscientists to integrate and explain experimental data obtained through neurophysiological and anatomical studies, thus providing a mechanism by which we can better understand and predict the principles of…

Neurons and Cognition · Quantitative Biology 2023-09-22 Parvin Zarei Eskikand , David B Grayden , Tatiana Kameneva , Anthony N Burkitt , Michael R Ibbotson

Multimodal imaging has transformed neuroscience research. While it presents unprecedented opportunities, it also imposes serious challenges. Particularly, it is difficult to combine the merits of the interpretability attributed to a simple…

Methodology · Statistics 2021-11-25 Xiaowu Dai , Lexin Li

Deep brain stimulation(DBS)has become an effective intervention for advanced Parkinson's disease, but the exact mechanism of DBS is still unclear. In this review, we discuss the history of DBS, the anatomy and internal architecture of the…

Neurons and Cognition · Quantitative Biology 2023-03-24 Yongtong Wu , Kejia Hu , Shenquan Liu

Alzheimer's disease (AD) is an irreversible and progressive brain disease that can be stopped or slowed down with medical treatment. Language changes serve as a sign that a patient's cognitive functions have been impacted, potentially…

Computation and Language · Computer Science 2018-04-19 Sweta Karlekar , Tong Niu , Mohit Bansal

Dementia has serious consequences for the daily life of the person affected due to the decline in the their cognitive, behavioral and functional abilities. Caring for people living with dementia can be challenging and distressing.…

Human-Computer Interaction · Computer Science 2024-04-16 Yong Ma , Oda Elise Nordberg , Jessica Hubbers , Yuchong Zhang , Arvid Rongve , Miroslav Bachinski , Morten Fjeld

In psychiatry, we often speak of constructing "models." Here we try to make sense of what such a claim might mean, starting with the most fundamental question: "What is (and isn't) a model?". We then discuss, in a concrete measurable sense,…

Neurons and Cognition · Quantitative Biology 2020-04-15 LR Mujica-Parodi , HH Strey

Information from neuroimaging examinations is increasingly used to support diagnoses of dementia, e.g., Alzheimer's disease. While current clinical practice is mainly based on visual inspection and feature engineering, Deep Learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Lisa Anita De Santi , Jörg Schlötterer , Michael Scheschenja , Joel Wessendorf , Meike Nauta , Vincenzo Positano , Christin Seifert

Alzheimer's disease (AD) is the most common long-term illness in elderly people. In recent years, deep learning has become popular in the area of medical imaging and has had a lot of success there. It has become the most effective way to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Mahin Khan Mahadi , Abdullah Abdullah , Jamal Uddin , Asif Newaz

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

Human-Computer Interaction · Computer Science 2025-08-28 Tomás Silva Santos Rocha , Anastasiia Mikhailova , Moreno I. Coco , José Santos-Victor

We present a practical health-theme machine learning (ML) application concerning `AI for social good' domain for `Producing Good Outcomes' track. In particular, the solution is concerning the problem of a potential elderly adult dementia…

Neurons and Cognition · Quantitative Biology 2019-11-28 Tomasz M. Rutkowski , Masato S. Abe , Marcin Koculak , Mihoko Otake-Matsuura

Our research focuses on analysing human activities according to a known behaviorist scenario, in case of noisy and high dimensional collected data. The data come from the monitoring of patients with dementia diseases by wearable cameras. We…

Although pain is frequent in old age, older adults are often undertreated for pain. This is especially the case for long-term care residents with moderate to severe dementia who cannot report their pain because of cognitive impairments that…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Siavash Rezaei , Abhishek Moturu , Shun Zhao , Kenneth M. Prkachin , Thomas Hadjistavropoulos , Babak Taati

Parkinsons Disease (PD) is a progressive neurological disorder that primarily affects motor functions and can lead to mild cognitive impairment (MCI) and dementia in its advanced stages. With approximately 10 million people diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Abu Saleh Musa Miah , taro Suzuki , Jungpil Shin

Background:Cognitive assessments represent the most common clinical routine for the diagnosis of Alzheimer's Disease (AD). Given a large number of cognitive assessment tools and time-limited office visits, it is important to determine a…

Quantitative Methods · Quantitative Biology 2020-11-16 Bo Peng , Xiaohui Yao , Shannon L. Risacher , Andrew J. Saykin , Li Shen , Xia Ning

Affective computing - combining sensor technology, machine learning, and psychology - have been studied for over three decades and is employed in AI-powered technologies to enhance emotional awareness in AI systems, and detect symptoms of…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-21 Anders Rolighed Larsen , Sneha Das , Nicole Nadine Lønfeldt , Paula Petcu , Line Clemmensen

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

Quantitative Methods · Quantitative Biology 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg
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