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A simulation methodology for predicting the time-course of enzymatic digestions is described. The model is based solely on the enzyme's subsite architecture and concomitant binding energies. This allows subsite binding energies to be used…

Biological Physics · Physics 2007-05-23 Jonathan J Hunt , Randall G Cameron , Martin A. K. Williams

Biomaterials such as protein or polysaccharide gels are known to behave qualitatively as soft solids and to rupture under an external load. Combining optical and ultrasonic imaging to shear rheology we show that the failure scenario of a…

Soft Condensed Matter · Physics 2014-08-21 Mathieu Leocmach , Christophe Perge , Thibaut Divoux , Sébastien Manneville

Colloidal nanocrystal gels can be assembled using a difunctional "linker" molecule to mediate bonding between nanocrystals. The conditions for gelation and the structure of the gel are controlled macroscopically by the linker concentration…

In this paper, the effects of changes in Sol concentration on the structural and optical properties of SnO2 Nanoparticles are studied through the Sol-Gel method. SnO2 Nanoparticles are produced from different SnO2 solution concentrations…

Mesoscale and Nanoscale Physics · Physics 2025-03-05 Ali Reza Razeghizadeh , Lila Zalaghi , Iraj Kazeminezhad , Vahdat Rafee

In recent years, significant effort has been devoted to developing smart materials whose mechanical properties can adapt under physical stimuli. Particulate colloidal gels, which behave as solids but can also flow under stress, have emerged…

Soft Condensed Matter · Physics 2025-11-19 Julien Bauland , Thomas Gibaud

We investigate the dynamics of alginate gels, an important class of biopolymer-based viscoelastic materials, by combining mechanical tests and non-conventional, time-resolved light scattering methods. Two relaxation modes are observed upon…

Soft Condensed Matter · Physics 2013-10-14 Domenico Larobina , Luca Cipelletti

During their travel through the gastrointestinal tract, ingestible antennas encounter detuning in their impedance response due to varying electromagnetic properties of the surrounding tissues. This paper investigates the possibility of…

We study light-activated quasi-2d gels made of a colloidal network doped with Janus particles. Following the gel formation, the internal dynamics of the gel are monitored before, during, and after the light activation. We monitor both the…

Soft Condensed Matter · Physics 2023-07-11 Mengshi Wei , Matan Ben Zion , Olivier Dauchot

We have investigated the rheology and structure of a gel formed from a mixture of non-Brownian particles and two immiscible liquids. The suspension of particles in a liquid undergoes gelation upon the addition of a small content of second,…

Soft Condensed Matter · Physics 2020-04-27 Sameer Huprikar , Saurabh Usgaonkar , Ashish K. Lele , Ashish V. Orpe

Revealing the structure of complex biological macromolecules, such as proteins, is an essential step for understanding the chemical mechanisms that determine the diversity of their functions. Synchrotron based x-ray crystallography and…

In this paper we investigate how the inclusion of scattering of the stellar radiation into a passive flaring disk model affects its structure and spectral energy distribution, and whether neglecting it could significantly decrease the model…

Astrophysics · Physics 2016-08-30 C. P. Dullemond , A. Natta

Suspensions of attractive particles form space-spanning networks that endow the suspension with solid-like behavior at rest. The microstructure of these colloidal gels depends sensitively on the shear history and on the path followed across…

Kinetic Monte Carlo approach is developed to study aspects of sintering of dispersed nanoparticles of bimodal size distributions. We explore mechanisms of neck development when sintering is initiated at elevated temperatures for nanosize…

Materials Science · Physics 2013-11-06 Vyacheslav Gorshkov , Vasily Kuzmenko , Vladimir Privman

Consumption of food in excess of the required optimal nutritional requirements has already resulted in a global crisis and this is from the perspective of human health, such as obesity, as well as food waste and sustainability. In order to…

Computational Engineering, Finance, and Science · Computer Science 2021-04-23 Dixon Vimalajeewa , Sasitharan Balasubramaniam

This research paper examined and re-evaluates the technological innovation, theory, structural dynamics and evolution of Pill Camera (Capsule Endoscopy) technology in redirecting the response manner of small bowel (intestine) examination in…

What can cells gain by using disordered, rather than folded, proteins in the architecture of their skeleton? Disordered proteins take multiple co-existing conformations, and often contain segments which act as random-walk-shaped polymers.…

Soft Condensed Matter · Physics 2016-10-05 Micha Kornreich , Eti Malka-Gibor , Ben Zuker , Adi Laser-Azogui , Roy Beck

Recently, we presented a framework for understanding protein structure based on the idea that simple constructs of holding hands or touching of objects can be used to rationalize the common characteristics of globular proteins. We developed…

Soft Condensed Matter · Physics 2023-06-21 Tatjana Škrbić , Achille Giacometti , Trinh X. Hoang , Amos Maritan , Jayanth R. Banavar

Ultrasound-induced degradation of soft polymeric colloids, like microgels, as well as a controlled drug release enabled by mechanoresponsive bonds, has recently attracted considerable attention. However, most examples in the literature…

Poly(N-isopropylacrylamide) (PNIPAM) is a synthetic polymer that is widely studied for its thermoresponsive character. However, recent works also reported evidence of a low temperature (protein-like) dynamical transition around 225 K in…

We investigate protein-protein interactions in solution by small-angle X-ray scattering (SAXS) and theoretical modeling. The structure factor for solutions of bovine pancreatic trypsin inhibitor (BPTI), myoglobin (Mb), and intestinal fatty…

Biological Physics · Physics 2014-08-29 Shuji Kaieda , Mikael Lund , Tomás S. Plivelic , Bertil Halle