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We have developed a novel scanning probe-based methodology to study cell biomechanics. The time dependence of the force exerted by the cell surface on a scanning probe at constant local deformation has been used to extract local…

Biological Physics · Physics 2009-04-20 Susana Moreno-Flores , Rafael Benitez , Maria dM Vivanco , Jose Luis Toca-Herrera

Tracer-kinetic analysis of dynamic contrast-enhanced magnetic resonance imaging data is commonly performed with the well-known Tofts model and nonlinear least squares (NLLS) regression. This approach yields point estimates of model…

Medical Physics · Physics 2020-01-08 Andreas Mittermeier , Birgit Ertl-Wagner , Jens Ricke , Olaf Dietrich , Michael Ingrisch

In various Computer Vision and Signal Processing applications, noise is typically perceived as a drawback of the image capturing system that ought to be removed. We, on the other hand, claim that image noise, just as texture, is important…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Renata Khasanova , Jan Wassenberg , Jyrki Alakuijala

During a surface acquisition process using 3D scanners, noise is inevitable and an important step in geometry processing is to remove these noise components from these surfaces (given as points-set or triangulated mesh). The noise-removal…

Graphics · Computer Science 2022-05-16 Sunil Kumar Yadav , Martin Skrodzki , Eric Zimmermann , Konrad Polthier

As the rapid growth of high-speed and deep-tissue imaging in biomedical research, it is urgent to find a robust and effective denoising method to retain morphological features for further texture analysis and segmentation. Conventional…

Image and Video Processing · Electrical Eng. & Systems 2019-04-16 Sheng-Yong Niu , Lun-Zhang Guo , Yue Li , Tzung-Dau Wang , Yu Tsao , Tzu-Ming Liu

The main goal of the LISA Pathfinder (LPF) mission is to fully characterize the acceleration noise models and to test key technologies for future space-based gravitational-wave observatories similar to the eLISA concept. The data analysis…

Burst denoising methods are crucial for enhancing images captured on handheld devices, but they often struggle with large motion or suffer from prohibitive computational costs. In this paper, we propose DenoiseGS, the first framework to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Yongsen Cheng , Yuanhao Cai , Yulun Zhang

Purpose: Recent developments in hardware design enable the use of Fast Field-Cycling (FFC) techniques in MRI to exploit the different relaxation rates at very low field strength, achieving novel contrast. The method opens new avenues for in…

Signal Processing · Electrical Eng. & Systems 2021-05-19 Markus Bödenler , Oliver Maier , Rudolf Stollberger , Lionel M. Broche , P. James Ross , Mary-Joan MacLeod , Hermann Scharfetter

In this paper, we propose a Bayesian spectral deconvolution method for absorption spectra. In conventional analysis, the noise mechanism of absorption spectral data is never considered appropriately. In that analysis, the least-squares…

Methodology · Statistics 2023-04-21 Tomohiro Nabika , Kenji Nagata , Shun Katakami , Masaichiro Mizumaki , Masato Okada

Noise is one of the primary sources of interference in seismic exploration. Many authors have proposed various methods to remove noise from seismic data; however, in the face of strong noise conditions, satisfactory results are often not…

Geophysics · Physics 2024-04-04 Junheng Peng , Yong Li , Yingtian Liu , Zhangquan Liao

Sonography techniques use multiple transducer elements for tissue visualization. Signals detected at each element are sampled prior to digital beamforming. The sampling rates required to perform high resolution digital beamforming are…

Information Theory · Computer Science 2013-07-25 Tanya Chernyakova , Yonina C. Eldar

Medical ultrasound provides images which are the spatial map of the tissue echogenicity. Unfortunately, an ultrasound image is a low-quality version of the expected Tissue Reflectivity Function (TRF) mainly due to the non-ideal Point Spread…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sobhan Goudarzi , Hassan Rivaz

An efficient technique is introduced for model inference of complex nonlinear dynamical systems driven by noise. The technique does not require extensive global optimization, provides optimal compensation for noise-induced errors and is…

Data Analysis, Statistics and Probability · Physics 2007-05-23 V. N. Smelyanskiy , D. A. Timucin , A. Bandrivskyy , D. G. Luchinsky

Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

Optics · Physics 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

Cryo Focused Ion-Beam Scanning Electron Microscopy (cryo FIB-SEM) enables three-dimensional and nanoscale imaging of biological specimens via a slice and view mechanism. The FIB-SEM experiments are, however, limited by a slow (typically,…

Current self-supervised denoising techniques achieve impressive results, yet their real-world application is frequently constrained by substantial computational and memory demands, necessitating a compromise between inference speed and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Tomáš Chobola , Julia A. Schnabel , Tingying Peng

The Fourier Basis Density Model (FBM) was recently introduced as a flexible probability model for band-limited distributions, i.e. ones which are smooth in the sense of having a characteristic function with limited support around the…

Information Theory · Computer Science 2025-05-12 Alfredo De la Fuente , Saurabh Singh , Jona Ballé

Non-negative matrix factorization (NMF) is widely used in many applications for dimensionality reduction. Inferring an appropriate number of factors for NMF is a challenging problem, and several approaches based on information criteria or…

Methodology · Statistics 2025-02-18 Alessandro Zito , Jeffrey W. Miller

The importance of regularization has been well established in image reconstruction -- which is the computational inversion of imaging forward model -- with applications including deconvolution for microscopy, tomographic reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Sanjay Viswanath , Manu Ghulyani , Muthuvel Arigovindan

The inherent noise in the observed (e.g., scanned) binary document image degrades the image quality and harms the compression ratio through breaking the pattern repentance and adding entropy to the document images. In this paper, we design…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Yandong Guo , Cheng Lu , Jan P. Allebach , Charles A. Bouman