English
Related papers

Related papers: Alignment-free Genomic Analysis via a Big Data Spa…

200 papers

Early diagnosis of Alzheimer's Disease (AD) is crucial for delaying its progression. While AI-based speech detection is non-invasive and cost-effective, it faces a critical data efficiency dilemma due to medical data scarcity and privacy…

Computation and Language · Computer Science 2026-02-17 Xiao Wei , Bin Wen , Yuqin Lin , Kai Li , Mingyang gu , Xiaobao Wang , Longbiao Wang , Jianwu Dang

High-dimensional approximate $K$ nearest neighbor search (AKNN) is a fundamental task for various applications, including information retrieval. Most existing algorithms for AKNN can be decomposed into two main components, i.e., candidate…

Databases · Computer Science 2024-12-03 Liwei Deng , Penghao Chen , Ximu Zeng , Tianfu Wang , Yan Zhao , Kai Zheng

Federated Domain Adaptation (FDA) is a federated learning (FL) approach that improves model performance at the target client by collaborating with source clients while preserving data privacy. FDA faces two primary challenges: domain shifts…

Machine Learning · Computer Science 2025-09-16 Mrinmay Sen , Ankita Das , Sidhant Nair , C Krishna Mohan

With the development of high-throughput technologies, genomics datasets rapidly grow in size, including functional genomics data. This has allowed the training of large Deep Learning (DL) models to predict epigenetic readouts, such as…

Genomics · Quantitative Biology 2024-05-30 Alexander Rakowski , Remo Monti , Viktoriia Huryn , Marta Lemanczyk , Uwe Ohler , Christoph Lippert

In the architecture of deep learning models, inspired by biological neurons, activation functions (AFs) play a pivotal role. They significantly influence the performance of artificial neural networks. By modulating the non-linear properties…

Machine Learning · Computer Science 2024-07-17 M. M. Hammad

In this paper, we propose a novel Automatic and Scalable Face Detector (ASFD), which is based on a combination of neural architecture search techniques as well as a new loss design. First, we propose an automatic feature enhance module…

Computer Vision and Pattern Recognition · Computer Science 2020-04-01 Bin Zhang , Jian Li , Yabiao Wang , Ying Tai , Chengjie Wang , Jilin Li , Feiyue Huang , Yili Xia , Wenjiang Pei , Rongrong Ji

Defect detection is a critical research area in artificial intelligence. Recently, synthetic data-based self-supervised learning has shown great potential on this task. Although many sophisticated synthesizing strategies exist, little…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Yuxuan Cai , Dingkang Liang , Dongliang Luo , Xinwei He , Xin Yang , Xiang Bai

Distance-based regression model, as a nonparametric multivariate method, has been widely used to detect the association between variations in a distance or dissimilarity matrix for outcomes and predictor variables of interest in genetic…

Statistics Theory · Mathematics 2022-03-14 Yuke Shi , Wei Zhang , Aiyi Liu , Qizhai Li

Approximate functional dependencies (AFDs) relax exact functional dependencies by tolerating a bounded degree of violation, making them suited for data quality auditing. Threshold-based discovery returns all dependencies above a…

Databases · Computer Science 2026-05-26 Xiaolong Wan , Xixian Han

Despite the striking success of general protein folding models such as AlphaFold2(AF2, Jumper et al. (2021)), the accurate computational modeling of antibody-antigen complexes remains a challenging task. In this paper, we first analyze…

Quantitative Methods · Quantitative Biology 2024-07-03 Ruidong Wu , Ruihan Guo , Rui Wang , Shitong Luo , Yue Xu , Jiahan Li , Jianzhu Ma , Qiang Liu , Yunan Luo , Jian Peng

With the emergence of the big data age, the issue of how to obtain valuable knowledge from a dataset efficiently and accurately has attracted increasingly attention from both academia and industry. This paper presents a Parallel Random…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-26 Jianguo Chen , Kenli Li , Zhuo Tang , Kashif Bilal , Shui Yu , Chuliang Weng , Keqin Li

Binary neural networks (BNNs) show promising utilization in cost and power-restricted domains such as edge devices and mobile systems. This is due to its significantly less computation and storage demand, but at the cost of degraded…

Neural and Evolutionary Computing · Computer Science 2022-06-08 Yanfei Li , Tong Geng , Samuel Stein , Ang Li , Huimin Yu

Fairness-aware domain generalization (FairDG) has emerged as a critical challenge for deploying trustworthy AI systems, particularly in scenarios involving distribution shifts. Traditional methods for addressing fairness have failed in…

Machine Learning · Computer Science 2025-05-01 Yujie Lin , Dong Li , Minglai Shao , Guihong Wan , Chen Zhao

The exponential growth of DNA sequencing data has outpaced traditional heuristic-based methods, which struggle to scale effectively. Efficient computational approaches are urgently needed to support large-scale similarity search, a…

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Motivation: Array Comparative Genomic Hybridization (aCGH) is used to scan the entire genome for variations in DNA copy number. A central task in the analysis of aCGH data is the segmentation into groups of probes sharing the same DNA copy…

Quantitative Methods · Quantitative Biology 2008-04-29 Erez Ben-Yaacov , Yonina Eldar

Federated learning has allowed the training of statistical models over remote devices without the transfer of raw client data. In practice, training in heterogeneous and large networks introduce novel challenges in various aspects like…

Machine Learning · Computer Science 2020-11-17 Dipankar Sarkar , Sumit Rai , Ankur Narang

In this paper, an Artificial Neural Network (ANN) technique is developed to find solution of celebrated Fractional order Differential Equations (FDE). Compared to integer order differential equation, FDE has the advantage that it can better…

Analysis of PDEs · Mathematics 2018-10-15 Susmita Mall , S. Chakraverty

We present an efficient phylogenetic reconstruction algorithm allowing insertions and deletions which provably achieves a sequence-length requirement (or sample complexity) growing polynomially in the number of taxa. Our algorithm is…

Probability · Mathematics 2013-02-25 Constantinos Daskalakis , Sebastien Roch

Along with current multi-scale based detectors, Feature Aggregation and Enhancement (FAE) modules have shown superior performance gains for cutting-edge object detection. However, these hand-crafted FAE modules show inconsistent…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 Jian Li , Bin Zhang , Yabiao Wang , Ying Tai , ZhenYu Zhang , Chengjie Wang , Jilin Li , Xiaoming Huang , Yili Xia