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Related papers: Multi-View Self-Attention for Interpretable Drug-T…

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Regression problems with time-series predictors are common in banking and many other areas of application. In this paper, we use multi-head attention networks to develop interpretable features and use them to achieve good predictive…

Machine Learning · Computer Science 2022-05-26 Tianjie Wang , Jie Chen , Joel Vaughan , Vijayan N. Nair

Significant differences in protein structures hinder the generalization of existing drug-target interaction (DTI) models, which often rely heavily on pre-learned binding principles or detailed annotations. In contrast, BioBridge designs an…

Machine Learning · Computer Science 2025-03-28 Xiaoqing Lian , Jie Zhu , Tianxu Lv , Shiyun Nie , Hang Fan , Guosheng Wu , Yunjun Ge , Lihua Li , Xiangxiang Zeng , Xiang Pan

Visual interest & affect prediction is a very interesting area of research in the area of computer vision. In this paper, we propose a transfer learning and attention mechanism based neural network model to predict visual interest &…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Deepanway Ghosal , Maheshkumar H. Kolekar

Confounding bias is a crucial problem when applying machine learning to practice, especially in clinical practice. We consider the problem of learning representations independent to multiple biases. In literature, this is mostly solved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Xianjing Liu , Bo Li , Esther Bron , Wiro Niessen , Eppo Wolvius , Gennady Roshchupkin

Real-world clinical problems are often characterized by multimodal data, usually associated with incomplete views and limited sample sizes in their cohorts, posing significant limitations for machine learning algorithms. In this work, we…

Technological advances have enabled the generation of unique and complementary types of data or views (e.g. genomics, proteomics, metabolomics) and opened up a new era in multiview learning research with the potential to lead to new…

Machine Learning · Computer Science 2024-02-19 Hengkang Wang , Han Lu , Ju Sun , Sandra E Safo

Neural language models are becoming the prevailing methodology for the tasks of query answering, text classification, disambiguation, completion and translation. Commonly comprised of hundreds of millions of parameters, these neural network…

Machine Learning · Computer Science 2020-05-13 Blaž Škrlj , Nika Eržen , Shane Sheehan , Saturnino Luz , Marko Robnik-Šikonja , Senja Pollak

Self-supervised representation learning (SSL) on biomedical networks provides new opportunities for drug discovery. However, how to effectively combine multiple SSL models is still challenging and has been rarely explored. Therefore, we…

Machine Learning · Computer Science 2022-12-20 Xiaoqi Wang , Yingjie Cheng , Yaning Yang , Yue Yu , Fei Li , Shaoliang Peng

Understanding the interaction between different drugs (drug-drug interaction or DDI) is critical for ensuring patient safety and optimizing therapeutic outcomes. Existing DDI datasets primarily focus on textual information, overlooking…

Machine Learning · Computer Science 2025-06-03 Tung-Lam Ngo , Ba-Hoang Tran , Duy-Cat Can , Trung-Hieu Do , Oliver Y. Chén , Hoang-Quynh Le

The Interaction between Drugs and Targets (DTI) in human body plays a crucial role in biomedical science and applications. As millions of papers come out every year in the biomedical domain, automatically discovering DTI knowledge from…

Computation and Language · Computer Science 2021-09-28 Yutai Hou , Yingce Xia , Lijun Wu , Shufang Xie , Yang Fan , Jinhua Zhu , Wanxiang Che , Tao Qin , Tie-Yan Liu

Learning distributed node representations in networks has been attracting increasing attention recently due to its effectiveness in a variety of applications. Existing approaches usually study networks with a single type of proximity…

Social and Information Networks · Computer Science 2017-09-21 Meng Qu , Jian Tang , Jingbo Shang , Xiang Ren , Ming Zhang , Jiawei Han

Complex or co-existing diseases are commonly treated using drug combinations, which can lead to higher risk of adverse side effects. The detection of polypharmacy side effects is usually done in Phase IV clinical trials, but there are still…

Machine Learning · Statistics 2019-05-03 Andreea Deac , Yu-Hsiang Huang , Petar Veličković , Pietro Liò , Jian Tang

We propose a novel inherently interpretable machine learning method that bases decisions on few relevant examples that we call prototypes. Our method, ProtoAttend, can be integrated into a wide range of neural network architectures…

Machine Learning · Computer Science 2019-09-27 Sercan O. Arik , Tomas Pfister

The attention mechanism plays an important role in the machine reading comprehension (MRC) model. Here, we describe a pipeline for building an MRC model with a pretrained language model and visualizing the effect of each attention zone in…

Computation and Language · Computer Science 2024-10-29 Yiming Cui , Wei-Nan Zhang , Ting Liu

Active visual exploration aims to assist an agent with a limited field of view to understand its environment based on partial observations made by choosing the best viewing directions in the scene. Recent methods have tried to address this…

Computer Vision and Pattern Recognition · Computer Science 2021-08-27 Soroush Seifi , Abhishek Jha , Tinne Tuytelaars

An important feature of pervasive, intelligent assistance systems is the ability to dynamically adapt to the current needs of their users. Hence, it is critical for such systems to be able to recognize those goals and needs based on…

Artificial Intelligence · Computer Science 2023-01-16 Nils Wilken , Lea Cohausz , Johannes Schaum , Stefan Lüdtke , Heiner Stuckenschmidt

Lung cancer is a condition where there is abnormal growth of malignant cells that spread in an uncontrollable fashion in the lungs. Some common treatment strategies are surgery, chemotherapy, and radiation which aren't the best options due…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Ann Rachel , Pranav M Pawar , Mithun Mukharjee , Raja M , Tojo Mathew

The human proteome contains a vast network of interacting kinases and substrates. Even though some kinases have proven to be immensely useful as therapeutic targets, a majority are still understudied. In this work, we present a novel…

Quantitative Methods · Quantitative Biology 2022-06-13 Sachin Gavali , Karen Ross , Chuming Chen , Julie Cowart , Cathy H. Wu

In this paper, a methodology is proposed that enables to analyze the sensitivity of the outcome of a therapy to unavoidable high dispersion of the patient specific parameters on one hand and to the choice of the parameters that define the…

Systems and Control · Electrical Eng. & Systems 2022-05-17 Mazen Alamir

In meta-learning approaches, it is difficult for a practitioner to make sense of what kind of representations the model employs. Without this ability, it can be difficult to both understand what the model knows as well as to make meaningful…

Machine Learning · Computer Science 2022-04-05 Pedro Sandoval-Segura , Wallace Lawson