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Receptor-ligand binding is a critical first step in signal transduction and the duration of the interaction can impact signal generation. In mammalian cells, clustering of receptors may be facilitated by heterogeneous zones of lipids, known…

Subcellular Processes · Quantitative Biology 2009-11-10 Manoj Gopalakrishnan , Kimberly Forsten-Williams , Matthew A. Nugent , Uwe C. Tauber

We study the formation of a colloidal gel by means of Molecular Dynamics simulations of a model for colloidal suspensions. A slowing down with gel-like features is observed at low temperatures and low volume fractions, due to the formation…

Soft Condensed Matter · Physics 2009-11-13 A. Fierro , E. Del Gado , A. de Candia , A. Coniglio

Adhesive interactions between elastic structures such as graphene sheets, carbon nanotubes, and microtubules have been shown to exhibit hysteresis due to irrecoverable energy loss associated with bond breakage, even in static…

Biological Physics · Physics 2021-02-02 Edvin Memet , Feodor Hilitski , Zvonimir Dogic , L. Mahadevan

In this paper we examine robust clustering behaviour with multiple nontrivial clusters for identically and globally coupled phase oscillators. These systems are such that the dynamics is completely determined by the number of oscillators N…

Dynamical Systems · Mathematics 2016-04-05 Asma Ismail , Peter Ashwin

Phase transitions are crucial in shaping the collective dynamics of a broad spectrum of natural systems across disciplines. Here, we report two distinct heterogeneous nucleation facilitating single-step and multi-step phase transitions to…

Adaptation and Self-Organizing Systems · Physics 2024-01-23 Akash Yadav , Jan Fialkowski , Rico Berner , V. K. Chandrasekar , D. V. Senthilkumar

Protein aggregation in cell membrane is vital for the majority of biological functions. Recent experimental results suggest that transmembrane domains of proteins such as $\alpha$-helices and $\beta$-sheets have different structural…

Biological Physics · Physics 2016-01-20 Hamidreza Jafarinia , Atefeh Khoshnood , Mir Abbas Jalali

The interplay between gravitational and dispersive forces in a multi-streamed medium leads to an effect which is exposed in the present note as the genuine driving force of stabilization of large-scale structure. The conception of `adhesive…

Astrophysics · Physics 2009-09-25 Thomas Buchert

Many biological tissues feature a heterogeneous network of fibers whose tensile and bending rigidity contribute substantially to these tissues' elastic properties. Rigidity percolation has emerged as a important paradigm for relating these…

We consider mechanically-induced pattern formation within the framework of a growing, planar, elastic rod attached to an elastic foundation. Through a combination of weakly nonlinear analysis and numerical methods, we identify how the shape…

Biological Physics · Physics 2020-06-02 Axel A. Almet , Helen M. Byrne , Philip K. Maini , Derek E. Moulton

Understanding cellular response to mechanical forces is immensely important for a plethora of biological processes. Focal adhesions are multi-molecular protein assemblies that connect the cell to the extracellular matrix and play a pivotal…

Biological Physics · Physics 2019-10-25 Rumi De

Adaptive coupling, where the coupling is dynamical and depends on the behaviour of the oscillators in a complex system, is one of the most crucial factors to control the dynamics and streamline various processes in complex networks. In this…

Adaptation and Self-Organizing Systems · Physics 2014-06-17 V. K. Chandrasekar , Jane H. Sheeba , B. Subash , M. Lakshmanan , J. Kurths

Current questions in ecology revolve around instabilities in the dynamics on spatial networks and particularly the effect of node heterogeneity. We extend the Master Stability Function formalism to inhomogeneous biregular networks having…

Populations and Evolution · Quantitative Biology 2022-04-27 Alexander Krauß , Thilo Gross , Barbara Drossel

Synthetic copolymers and biopolymers, such as polypeptides and double-stranded DNA, often exhibit strong variations in bending stiffness along their contour, which can significantly impact conformational behavior at larger scales. To…

Soft Condensed Matter · Physics 2025-11-04 Yannick Witzky , Friederike Schmid , Arash Nikoubashman

Many animal groups are heterogeneous and may even consist of individuals of different species, called mixed-species flocks. Mathematical and computational models of collective animal movement behaviour, however, typically assume that groups…

Adaptation and Self-Organizing Systems · Physics 2019-03-27 Gokul G. Nair , Athmanathan Senthilnathan , Srikanth K. Iyer , Vishwesha Guttal

Biological adhesion is a critical mechanical function of complex organisms operating at multiple scales. At the cellular scale, cell-cell adhesion is remarkably tunable to enable both cohesion and malleability during development,…

Soft Condensed Matter · Physics 2022-03-07 Dimitri Kaurin , Pradeep K. Bal , Marino Arroyo

We analyze the collective dynamics of an ensemble of globally coupled, externally forced, identical mechanical oscillators with cubic nonlinearity. Focus is put on solutions where the ensemble splits into two internally synchronized…

Adaptation and Self-Organizing Systems · Physics 2021-12-06 Raúl I. Sosa , Damián H. Zanette

Dynamical systems on networks with adaptive couplings appear naturally in real-world systems such as power grid networks, social networks as well as neuronal networks. We investigate a paradigmatic system of adaptively coupled phase…

Adaptation and Self-Organizing Systems · Physics 2019-12-20 Rico Berner , Eckehard Schöll , Serhiy Yanchuk

It is shown that a compound elastic structure, which displays a dynamic instability, may be designed as the union (or 'fusion') of two structures which are stable when separately analyzed. The compound elastic structure has two degrees of…

Classical Physics · Physics 2023-01-16 Marco Rossi , Andrea Piccolroaz , Davide Bigoni

The competition of depletion attractions and longer-ranged repulsions between colloidal particles in colloid-polymer mixtures leads to the formation of heterogeneous gel-like structures. For instance, gel networks, i.e., states where the…

Soft Condensed Matter · Physics 2021-06-24 Matthias Gimperlein , Michael Schmiedeberg

Soft-granular media, such as dense emulsions, foams or tissues, exhibit either fluid- or solid-like properties depending on the applied external stresses. Whereas bulk rheology of such materials has been thoroughly investigated, the…

Soft Condensed Matter · Physics 2024-07-04 Michal Bogdan , Jesus Pineda , Mihir Durve , Leon Jurkiewicz , Sauro Succi , Giovanni Volpe , Jan Guzowski