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The software development process has evolved with respect to the problems in developing large and complex applications. There is a paradigm shift towards collaborative development, which necessitates the need to evaluate this approach. A…

Software Engineering · Computer Science 2019-04-02 Robail Yasrab , Javed Ferzund , Saad Razzaq

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

Medical Physics · Physics 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

One of the goals of software design is to model a system in such a way that it is easily understandable. Nowadays the tendency for software development is changing from manual coding to automatic code generation; it is becoming model-based.…

Software Engineering · Computer Science 2015-03-13 N Md Jubair basha , Salman Abdul Moiz , Mohammed Rizwanullah

Software engineering research benefited for decades from openly available tools, accessible systems, and problems that could be studied at modest scale. Today, many of the most relevant software systems are large, proprietary, and embedded…

Software Engineering · Computer Science 2026-03-24 Diomidis Spinellis , Zoe Kotti

The landscape of workflow systems for scientific applications is notoriously convoluted with hundreds of seemingly equivalent workflow systems, many isolated research claims, and a steep learning curve. To address some of these challenges…

The vast majority of the long tail of scientific software, the myriads of tools that implement the many analysis and visualization methods for different scientific fields, is highly specialized, purpose-built for a research project, and has…

Software Engineering · Computer Science 2013-09-10 Daisie Huang , Hilmar Lapp

Using machine learning in clinical practice poses hard requirements on explainability, reliability, replicability and robustness of these systems. Therefore, developing reliable software for monitoring critically ill patients requires close…

Software Engineering · Computer Science 2021-03-16 Miroslaw Staron , Helena Odenstedt Hergés , Silvana Naredi , Linda Block , Ali El-Merhi , Richard Vithal , Mikael Elam

In the past decade, enormous progress has been made in advancing the state-of-the-art in bioimage analysis - a young computational field that works in close collaboration with the life sciences on the quantitative analysis of scientific…

Other Quantitative Biology · Quantitative Biology 2023-07-11 Joran Deschamps , Damian Dalle Nogare , Florian Jug

A low cost remote imaging platform for biological applications was developed. The "Picroscope" is a device that allows the user to perform longitudinal imaging studies on multi-well cell culture plates. Here we present the network…

Workflows in biomolecular science are very important as they are intricately intertwined with the scientific outcomes, as well as algorithmic and methodological innovations. The use and effectiveness of workflow tools to meet the needs of…

Software Engineering · Computer Science 2019-05-29 Levi N. Naden , Sam Ellis , Shantenu Jha

High-quality research software is a cornerstone of modern scientific progress, enabling researchers to analyze complex data, simulate phenomena, and share reproducible results. However, creating such software requires adherence to best…

Software Engineering · Computer Science 2025-07-23 Nasir U. Eisty , David E. Bernholdt , Alex Koufos , David J. Luet , Miranda Mundt

Research software -- specialist software used to support or undertake research -- is of huge importance to researchers. It contributes to significant advances in the wider world and requires collaboration between people with diverse skills…

Software Engineering · Computer Science 2021-06-22 Neil P. Chue Hong , Jeremy Cohen , Caroline Jay

{\mu}Manager, an open-source microscopy acquisition software, has been an essential tool for many microscopy experiments over the past 15 years, but is not easy to use for experiments in which image acquisition and analysis are closely…

Quantitative Methods · Quantitative Biology 2024-02-12 Henry Pinkard , Nico Stuurman , Laura Waller

We pose that microscopy offers an ideal real-world experimental environment for the development and deployment of active Bayesian and reinforcement learning methods. Indeed, the tremendous progress achieved by machine learning (ML) and…

Disordered Systems and Neural Networks · Physics 2022-10-14 Sergei V. Kalinin , Rama Vasudevan , Yongtao Liu , Ayana Ghosh , Kevin Roccapriore , Maxim Ziatdinov

Microscopes are vital pieces of equipment in much of biological research and medical diagnostics. However, access to a microscope can represent a bottleneck in research, especially in lower-income countries. `Smart' computer controlled…

Instrumentation and Detectors · Physics 2022-07-08 Samuel McDermott , Filip Ayazi , Joel Collins , Joe Knapper , Julian Stirling , Richard Bowman , Pietro Cicuta

The adoption of DevOps practices in embedded systems and firmware development is emerging as a response to the growing complexity of modern hardware--software co-designed products. Unlike cloud-native applications, embedded systems…

Software Engineering · Computer Science 2025-07-02 Parthiv Katapara , Anand Sharma

Research software plays a crucial role in advancing scientific knowledge, but ensuring its sustainability, maintainability, and long-term viability is an ongoing challenge. To address these concerns, the Sustainable Research Software…

Software is foundationally important to scientific and social progress, however, traditional acknowledgment of the use of others' work has not adapted in step with the rapid development and use of software in research. This report outlines…

Digital Libraries · Computer Science 2023-02-16 Daina Bouquin , Ana Trisovic , Oliver Bertuch , Elena Colón-Marrero