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In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

Lesion detection in brain Magnetic Resonance Images (MRI) remains a challenging task. State-of-the-art approaches are mostly based on supervised learning making use of large annotated datasets. Human beings, on the other hand, even…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Xiaoran Chen , Ender Konukoglu

We propose a novel unsupervised out-of-distribution detection method for medical images based on implicit fields image representations. In our approach, an auto-decoder feed-forward neural network learns the distribution of healthy images…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Sergio Naval Marimont , Giacomo Tarroni

Finding automatically multiple lesions in large images is a common problem in medical image analysis. Solving this problem can be challenging if, during optimization, the automated method cannot access information about the location of the…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Florian Dubost , Hieab Adams , Pinar Yilmaz , Gerda Bortsova , Gijs van Tulder , M. Arfan Ikram , Wiro Niessen , Meike Vernooij , Marleen de Bruijne

Automatic skin lesion segmentation on dermoscopic images is an essential component in computer-aided diagnosis of melanoma. Recently, many fully supervised deep learning based methods have been proposed for automatic skin lesion…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Pheng-Ann Heng

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

A wide range of systems exhibit high dimensional incomplete data. Accurate estimation of the missing data is often desired, and is crucial for many downstream analyses. Many state-of-the-art recovery methods involve supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2019-03-15 Adrian V. Dalca , John Guttag , Mert R. Sabuncu

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

In numerous practical applications, especially in medical image reconstruction, it is often infeasible to obtain a large ensemble of ground-truth/measurement pairs for supervised learning. Therefore, it is imperative to develop unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2021-03-31 Subhadip Mukherjee , Ozan Öktem , Carola-Bibiane Schönlieb

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas

This work addresses image restoration tasks through the lens of inverse problems using unpaired datasets. In contrast to traditional approaches -- which typically assume full knowledge of the forward model or access to paired degraded and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Giacomo Meanti , Thomas Ryckeboer , Michael Arbel , Julien Mairal

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Eduardo Pinho , Carlos Costa

Bias field, which is caused by imperfect MR devices or imaged objects, introduces intensity inhomogeneity into MR images and degrades the performance of MR image analysis methods. Many retrospective algorithms were developed to facilitate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Dong Liang , Xingyu Qiu , Kuanquan Wang , Gongning Luo , Wei Wang , Yashu Liu

Imaging is a standard example of an inverse problem, where the task of reconstructing a ground truth from a noisy measurement is ill-posed. Recent state-of-the-art approaches for imaging use deep learning, spearheaded by unrolled and…

Unsupervised Anomaly Detection has become a popular method to detect pathologies in medical images as it does not require supervision or labels for training. Most commonly, the anomaly detection model generates a "normal" version of an…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Johannes Paetzold , Georgios Kaissis , Daniel Rueckert

We consider the problem of segmenting a biomedical image into anatomical regions of interest. We specifically address the frequent scenario where we have no paired training data that contains images and their manual segmentations. Instead,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Adrian V. Dalca , John Guttag , Mert R. Sabuncu

Current unsupervised anomaly localization approaches rely on generative models to learn the distribution of normal images, which is later used to identify potential anomalous regions derived from errors on the reconstructed images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Julio Silva-Rodríguez , Valery Naranjo , Jose Dolz

Supervised learning with a convolutional neural network is recognized as a powerful means of image restoration. However, most such methods have been designed for application to grayscale and/or color images; therefore, they have limited…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Ryuji Imamura , Tatsuki Itasaka , Masahiro Okuda

Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ziyun Liang , Xiaoqing Guo , Wentian Xu , Yasin Ibrahim , Natalie Voets , Pieter M Pretorius , J. Alison Noble , Konstantinos Kamnitsas

Oversight in medical images is a crucial problem, and timely reporting of medical images is desired. Therefore, an all-purpose anomaly detection method that can detect virtually all types of lesions/diseases in a given image is strongly…

Image and Video Processing · Electrical Eng. & Systems 2020-10-21 H. Shibata , S. Hanaoka , Y. Nomura , T. Nakao , I. Sato , D. Sato , N. Hayashi , O. Abe
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