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Modeling disease progression in healthcare administrative databases is complicated by the fact that patients are observed only at irregular intervals when they seek healthcare services. In a longitudinal cohort of 76,888 patients with…

Machine Learning · Computer Science 2018-12-04 Aman Verma , Guido Powell , Yu Luo , David Stephens , David L. Buckeridge

Key features of biological activity can often be captured by transitions between a finite number of semi-stable states that correspond to behaviors or decisions. We present here a broad class of dynamical systems that are ideal for modeling…

Dynamical Systems · Mathematics 2022-12-14 Megan Morrison , Lai-Sang Young

In this paper, we study state-feedback control of Markov jump linear systems with partial information. In particular, we assume that the controller can only access the mode signals according to a hidden-Markov observation process. Our…

Optimization and Control · Mathematics 2019-03-19 Masaki Ogura , Ahmet Cetinkaya , Tomohisa Hayakawa , Victor M. Preciado

State-space models are commonly used to describe different forms of ecological data. We consider the case of count data with observation errors. For such data the system process is typically multi-dimensional consisting of coupled Markov…

Methodology · Statistics 2017-08-15 Axel Finke , Ruth King , Alexandros Beskos , Petros Dellaportas

Real-world dynamical systems often consist of multiple stochastic subsystems that interact with each other. Modeling and forecasting the behavior of such dynamics are generally not easy, due to the inherent hardness in understanding the…

Machine Learning · Computer Science 2020-01-14 Fan Yang , Ling Chen , Fan Zhou , Yusong Gao , Wei Cao

We present a study using new computational methods, based on a novel combination of machine learning for inferring admixture hidden Markov models and probabilistic model checking, to uncover interaction styles in a mobile app. These styles…

Human-Computer Interaction · Computer Science 2023-05-04 Oana Andrei , Muffy Calder , Matthew Chalmers , Alistair Morrison

The effective control of infectious diseases relies on accurate assessment of the impact of interventions, which is often hindered by the complex dynamics of the spread of disease. A Beta-Dirichlet switching state-space transmission model…

Methodology · Statistics 2024-04-30 Jingxue Feng , Liangliang Wang

Motivated by the analysis of accelerometer data, we introduce a specific finite mixture of hidden Markov models with particular characteristics that adapt well to the specific nature of this type of data. Our model allows for the…

Methodology · Statistics 2020-12-25 Marie du Roy de Chaumaray , Matthieu Marbac , Fabien Navarro

In this paper we study the state-feedback stabilization of a discrete-time Markov jump linear system when the observation of the Markov chain of the system, called the Markov state, is time-randomized by another Markov chain. Embedding the…

Optimization and Control · Mathematics 2016-11-04 Masaki Ogura , Ahmet Cetinkaya

We consider synchronization of chaotic systems coupled indirectly through a common environmnet where the environment has an intrinsic dynmics of its own modulated via feedback from the systems. We find that a rich vareity of synchronization…

Chaotic Dynamics · Physics 2010-05-05 V. Resmi , G. Ambika , R. E. Amritkar

A state-space model is a time-series model that has an unobserved latent process from which we take noisy measurements over time. The observations are conditionally independent given the latent process and the latent process itself is…

Methodology · Statistics 2025-10-07 Paul Fearnhead , Chris Sherlock

Recent developments in automated tracking allow uninterrupted, high-resolution recording of animal trajectories, sometimes coupled with the identification of stereotyped changes of body pose or other behaviors of interest. Analysis and…

Populations and Evolution · Quantitative Biology 2018-07-04 Katarina Bodova , Gabriel J. Mitchell , Roy Harpaz , Elad Schneidman , Gasper Tkacik

This chapter presents an introduction to Markovian modeling for the analysis of sequence data. Contrary to the deterministic approach seen in the previous sequence analysis chapters, Markovian models are probabilistic models, focusing on…

Methodology · Statistics 2023-09-18 Jouni Helske , Satu Helske , Mohammed Saqr , Sonsoles López-Pernas , Keefe Murphy

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Survival competing risks models are very useful for studying the incidence of diseases whose occurrence competes with other possible diseases or health conditions. These models perform properly when working with terminal events, such as…

Applications · Statistics 2021-04-09 Fran Llopis-Cardona , Carmen Armero , Gabriel Sanfélix-Gimeno

We describe a systematic approach to construct coarse-grained Markov state models from molecular dynamics data of systems driven into a non-equilibrium steady state. We apply this method to study the globule-stretch transition of a single…

Soft Condensed Matter · Physics 2017-02-28 Fabian Knoch , Thomas Speck

Regime-switching models, in particular Hidden Markov Models (HMMs) where the switching is driven by an unobservable Markov chain, are widely-used in financial applications, due to their tractability and good econometric properties. In this…

Statistical Finance · Quantitative Finance 2016-02-18 Vikram Krishnamurthy , Elisabeth Leoff , Jörn Sass

Analyzing synchronized nonlinear oscillators is one of the most important and attractive topics in nonlinear science. By understanding the interactions between the oscillators, we can figure out the synchronization process. A promising…

Adaptation and Self-Organizing Systems · Physics 2025-02-05 Yuka Hashimoto , Masahiro Ikeda , Hiroya Nakao , Yoshinobu Kawahara

We compare different selection criteria to choose the number of latent states of a multivariate latent Markov model for longitudinal data. This model is based on an underlying Markov chain to represent the evolution of a latent…

Methodology · Statistics 2012-12-04 Silvia Bacci , Silvia Pandolfi , Fulvia Pennoni

Transformer language models (LMs) exhibit behaviors -- from storytelling to code generation -- that seem to require tracking the unobserved state of an evolving world. How do they do this? We study state tracking in LMs trained or…

Computation and Language · Computer Science 2025-11-03 Belinda Z. Li , Zifan Carl Guo , Jacob Andreas