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Related papers: Prediction of Epilepsy Development in Traumatic Br…

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Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy

Introduction: Approximately 23 million or 30% of epilepsy patients worldwide suffer from drug-resistant epilepsy (DRE). The unpredictability of seizure occurrences, which causes safety issues as well as social concerns, restrict the…

Machine Learning · Computer Science 2024-10-10 Shriya Jaddu , Sidh Jaddu , Camilo Gutierrez , Quincy K. Tran

Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae. Blast pressure waves can cause TBI without penetrating wounds or blunt force…

Medical Physics · Physics 2008-08-12 Amy Courtney , Michael Courtney

Traumatic Brain Injury (TBI) is a common cause of death and disability. However, existing tools for TBI diagnosis are either subjective or require extensive clinical setup and expertise. The increasing affordability and reduction in size of…

Signal Processing · Electrical Eng. & Systems 2021-02-01 Navjodh Singh Dhillon , Agustinus Sutandi , Manoj Vishwanath , Miranda M. Lim , Hung Cao , Dong Si

In this study, we developed and tested machine learning models to predict epilepsy surgical outcome using noninvasive clinical and demographic data from patients. Methods: Seven dif-ferent categorization algorithms were used to analyze the…

Traumatic brain injury (TBI) disrupts thalamocortical connectivity, contributing to cognitive impairment and post-traumatic epilepsy (PTE). This study presents a novel tractography-based framework that leverages diffusion maps to capture…

Quantitative Methods · Quantitative Biology 2025-10-21 Akul Sharma , Anand A. Joshi , Richard M. Leahy

Epilepsy surgery, particularly for temporal lobe epilepsy (TLE), remains a vital treatment option for patients with drug-resistant seizures. However, accurately predicting surgical outcomes remains a significant challenge. This study…

Neurons and Cognition · Quantitative Biology 2025-07-22 Martin Guillemaud , Alice Longhena , Louis Cousyn , Valerio Frazzini , Bertrand Mathon , Vincent Navarro , Mario Chavez

Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…

Patients with traumatic brain injury (TBI) often experience pathological increases in intracranial pressure (ICP), leading to intracranial hypertension (tIH), a common and serious complication. Early warning of an impending rise in ICP…

Controlling the surrounding world and predicting future events has always seemed like a dream, but that could become a reality using a Brain-Computer/Machine Interface (BCI/BMI). Epilepsy is a group of neurological diseases characterized by…

Signal Processing · Electrical Eng. & Systems 2019-06-10 Zaghloul Saad Zaghloul , Magdy Bayoumi

Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferred from diffusion-weighted MRI (DWI). However, publicly…

The accurate prognosis for traumatic brain injury (TBI) patients is difficult yet essential to inform therapy, patient management, and long-term after-care. Patient characteristics such as age, motor and pupil responsiveness, hypoxia and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Margherita Rosnati , Eyal Soreq , Miguel Monteiro , Lucia Li , Neil S. N. Graham , Karl Zimmerman , Carlotta Rossi , Greta Carrara , Guido Bertolini , David J. Sharp , Ben Glocker

Objective: Epilepsy is one of the most prevalent neurological diseases among humans and can lead to severe brain injuries, strokes, and brain tumors. Early detection of seizures can help to mitigate injuries, and can be used to aid the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-20 Theekshana Dissanayake , Tharindu Fernando , Simon Denman , Sridha Sridharan , Clinton Fookes

Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive…

Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…

Machine Learning · Computer Science 2024-10-29 Lucas Steinmetz , Shivam Maheshwari , Garik Kazanjian , Abigail Loyson , Tyler Alexander , Venkat Margapuri , C. Nataraj

Epilepsy is a neurological disorder classified as the second most serious neurological disease known to humanity, after stroke. Localization of the epileptogenic zone is an important step for epileptic patient treatment, which starts with…

Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…

We present a method to estimate a multivariate Gaussian distribution of diffusion tensor features in a set of brain regions based on a small sample of healthy individuals, and use this distribution to identify imaging abnormalities in…

Applications · Statistics 2017-04-24 Matineh Shaker , Deniz Erdogmus , Jennifer Dy , Sylvain Bouix

Background: Ventilator-associated pneumonia (VAP) in traumatic brain injury (TBI) patients poses a significant mortality risk and imposes a considerable financial burden on patients and healthcare systems. Timely detection and…

Machine Learning · Computer Science 2024-08-05 Negin Ashrafi , Armin Abdollahi , Maryam Pishgar

In clinical practice, electroencephalography (EEG) plays an important role in the diagnosis of epilepsy. EEG-based computer-aided diagnosis of epilepsy can greatly improve the ac-curacy of epilepsy detection while reducing the workload of…

Signal Processing · Electrical Eng. & Systems 2026-03-24 Andong Li , Zhaohong Deng , Qiongdan Lou
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