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Multiple viruses are widely studied because of their negative effect on the health of host as well as on whole population. The dynamics of coinfection is important in this case. We formulated a SIR model that describes the coinfection of…

Dynamical Systems · Mathematics 2019-05-14 Samia Ghersheen , Vladimir Kozlov , Vladimir G. Tkachev , Uno Wennergren

We analyze evolutionary dynamics in a confluent, branching cellular population, such as in a growing duct, vasculature, or in a branching microbial colony. We focus on the coarse-grained features of the evolution and build a statistical…

Populations and Evolution · Quantitative Biology 2022-02-15 Adam S. Bryant , Maxim O. Lavrentovich

We study the population dynamics of lytic viruses which replicate slowly in dividing host cells within an organism or cell culture, and find a range of viral replication rates that allows viruses to persist, avoiding extinction of host…

Populations and Evolution · Quantitative Biology 2013-05-29 Jingshan Zhang , Eugene I. Shakhnovich

We present a flexible branching process model for cell population dynamics in synchrony/time-series experiments used to study important cellular processes. Its formulation is constructive, based on an accounting of the unique cohorts in the…

Applications · Statistics 2010-09-30 David A. Orlando , Edwin S. Iversen , Alexander J. Hartemink , Steven B. Haase

The first chapter concerns monotype population models. We first study general birth and death processes and we give non-explosion and extinction criteria, moment computations and a pathwise representation. We then show how different scales…

Probability · Mathematics 2017-07-06 Vincent Bansaye , Sylvie Méléard

We propose two models of the evolution of a pair of competing populations. Both are lattice based. The first is a compromise between fully spatial models, which do not appear amenable to analytic results, and interacting particle system…

Probability · Mathematics 2009-09-29 Jochen Blath , Alison Etheridge , Mark Meredith

We present a population control method with sampling and regulation steps for Monte Carlo particles involved in the numerical simulation of a transport equation. We recall in the first section the difficulties related to the variance…

Numerical Analysis · Mathematics 2023-01-31 Laetitia Laguzet , Gabriel Turinici

We present a stochastic model for two successive SIR (Susceptible, Infectious, Recovered) epidemics in the same network structured population. Individuals infected during the first epidemic might have (partial) immunity for the second one.…

Populations and Evolution · Quantitative Biology 2024-10-29 Frank Ball , Abid Ali Lashari , David Sirl , Pieter Trapman

A branching process in varying environment with generation-dependent immigration is a modification of the standard branching process in which immigration is allowed and the reproduction and immigration laws may vary over the generations.…

Probability · Mathematics 2024-01-31 Miguel González , Goetz Kersting , Carmen Minuesa , Inés del Puerto

We study a simple model of DNA evolution in a growing population of cells. Each cell contains a nucleotide sequence which randomly mutates at cell division. Cells divide according to a branching process. Following typical parameter values…

Probability · Mathematics 2020-06-05 David Cheek , Tibor Antal

We study a size-structured population model in which individual cells grow at a rate determined by a fluctuating internal variable (e.g., gene expression levels). Many previous models of phenotypically heterogeneous populations can be…

Statistical Mechanics · Physics 2026-04-06 Ethan Levien , Yaïr Hein , Farshid Jafarpour

This study builds upon a model proposed by Joanny and collaborators that examines the dynamics of interfaces between two distinct cell populations, particularly during tumor growth in healthy tissues. This framework leads to the…

Analysis of PDEs · Mathematics 2024-09-20 Juan Campos , Carlos Pulido , Juan Soler

We consider the qualitative behavior of a mathematical model for transmission dynamics with two nonlinear stages of contagion. The proposed model is inspired by phenomena occurring in epidemiology (spread of infectious diseases) or social…

Dynamical Systems · Mathematics 2021-05-04 Julian Heidecke , Maria Vittoria Barbarossa

The emergence of a predominant phenotype within a cell population is often triggered by a rare accumulation of DNA mutations in a single cell. For example, tumors may be initiated by a single cell in which multiple mutations cooperate to…

Tissues and Organs · Quantitative Biology 2018-11-21 Philip Greulich , Benjamin D. Simons

We consider a minimal go-or-grow model of cell invasion, whereby cells can either proliferate, following logistic growth, or move, via linear diffusion, and phenotypic switching between these two states is density-dependent. Formal analysis…

Analysis of PDEs · Mathematics 2024-04-18 Carles Falcó , Rebecca M. Crossley , Ruth E. Baker

Percolation on two-dimensional small-world networks has been proposed as a model for the spread of plant diseases. In this paper we give an analytic solution of this model using a combination of generating function methods and high-order…

Statistical Mechanics · Physics 2009-11-07 M. E. J. Newman , I. Jensen , R. M. Ziff

Multipartite viruses replicate through a puzzling evolutionary strategy. Their genome is segmented into two or more parts, and encapsidated in separate particles that appear to propagate independently. Completing the replication cycle,…

Physics and Society · Physics 2019-03-26 Eugenio Valdano , Susanna Manrubia , Sergio Gómez , Alex Arenas

We study a nonlinear branching diffusion process in the sense of McKean, i.e., where particles are subjected to a mean-field interaction. We consider first a strong formulation of the problem and we provide an existence and uniqueness…

Probability · Mathematics 2024-09-12 Julien Claisse , Jiazhi Kang , Xiaolu Tan

Cell differentiation in multicellular organisms is a complex process whose mechanism can be understood by a reductionist approach, in which the individual processes that control the generation of different cell types are identified.…

The aim of the paper is to describe two models of Covid-19 infection dynamics. For this purpose a special class of branching processes with two types of individuals is considered. These models are intended to use only the observed daily…

Populations and Evolution · Quantitative Biology 2020-05-05 Nikolay M. Yanev , Vessela K. Stoimenova , Dimitar V. Atanasov