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200 papers

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

Computer Vision and Pattern Recognition · Computer Science 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

While deep learning methods have shown great success in medical image analysis, they require a number of medical images to train. Due to data privacy concerns and unavailability of medical annotators, it is oftentimes very difficult to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Yue Yang , Pengtao Xie

Trained using only image class label, deep weakly supervised methods allow image classification and ROI segmentation for interpretability. Despite their success on natural images, they face several challenges over histology data where ROI…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Histopathology images are gigapixel-sized and include features and information at different resolutions. Collecting annotations in histopathology requires highly specialized pathologists, making it expensive and time-consuming.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Jin Li , Deepta Rajan , Chintan Shah , Dinkar Juyal , Shreya Chakraborty , Chandan Akiti , Filip Kos , Janani Iyer , Anand Sampat , Ali Behrooz

In biomedical imaging, deep learning-based methods are state-of-the-art for every modality (virtual slides, MRI, etc.) In histopathology, these methods can be used to detect certain biomarkers or classify lesions. However, such techniques…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Adrien Nivaggioli , Nicolas Pozin , Rémy Peyret , Stéphane Sockeel , Marie Sockeel , Nicolas Nerrienet , Marceau Clavel , Clara Simmat , Catherine Miquel

Histopathologic Images (HI) are the gold standard for evaluation of some tumors. However, the analysis of such images is challenging even for experienced pathologists, resulting in problems of inter and intra observer. Besides that, the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Jonathan de Matos , Alceu de Souza Britto , Luiz E. S. Oliveira , Alessandro L. Koerich

Progress in digital pathology is hindered by high-resolution images and the prohibitive cost of exhaustive localized annotations. The commonly used paradigm to categorize pathology images is patch-based processing, which often incorporates…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Thomas Stegmüller , Behzad Bozorgtabar , Antoine Spahr , Jean-Philippe Thiran

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Training neural networks with high-quality pixel-level annotation in histopathology whole-slide images (WSI) is an expensive process due to gigapixel resolution of WSIs. However, recent advances in self-supervised learning have shown that…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Nohemi Sofia Leon Contreras , Marina D'Amato , Francesco Ciompi , Clement Grisi , Witali Aswolinskiy , Simona Vatrano , Filippo Fraggetta , Iris Nagtegaal

In histopathological image analysis, feature extraction for classification is a challenging task due to the diversity of histology features suitable for each problem as well as presence of rich geometrical structure. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Tiep H. Vu , Hojjat S. Mousavi , Vishal Monga , UK Arvind Rao , Ganesh Rao

Segmentation of anatomical structures and pathologies is inherently ambiguous. For instance, structure borders may not be clearly visible or different experts may have different styles of annotating. The majority of current state-of-the-art…

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Deep learning methods have shown promise in classifying breast cancer histopathology images, but their performance often declines with limited annotated data, a critical challenge in medical imaging due to the high cost and expertise…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Liu Suxing , Byungwon Min

Image classifiers are typically scored on their test set accuracy, but high accuracy can mask a subtle type of model failure. We find that high scoring convolutional neural networks (CNNs) on popular benchmarks exhibit troubling pathologies…

Machine Learning · Computer Science 2021-12-08 Brandon Carter , Siddhartha Jain , Jonas Mueller , David Gifford

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

Transfer learning is crucial for medical imaging, yet the selection of source datasets often relies on researchers' intuition rather than systematic principles, which can impact the generalizability of algorithms and, thus, patient…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Yucheng Lu , Hubert Dariusz Zając , Veronika Cheplygina , Amelia Jiménez-Sánchez

Image-to-image translation is a technique that focuses on transferring images from one domain to another while maintaining the essential content representations. In recent years, image-to-image translation has gained significant attention…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Xixian Wu , Dian Chao , Yang Yang