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We propose a framework for verifiable and compositional reinforcement learning (RL) in which a collection of RL subsystems, each of which learns to accomplish a separate subtask, are composed to achieve an overall task. The framework…

Machine Learning · Computer Science 2022-05-16 Cyrus Neary , Christos Verginis , Murat Cubuktepe , Ufuk Topcu

Chemical space exploration underlies drug discovery, yet most generative models treat chemical space as a fixed, implicitly learned distribution, focusing on sampling molecules rather than deliberately designing the space itself. We…

Feature selection aims to preprocess the target dataset, find an optimal and most streamlined feature subset, and enhance the downstream machine learning task. Among filter, wrapper, and embedded-based approaches, the reinforcement learning…

Artificial Intelligence · Computer Science 2025-09-17 Weiliang Zhang , Xiaohan Huang , Yi Du , Ziyue Qiao , Qingqing Long , Zhen Meng , Yuanchun Zhou , Meng Xiao

Respondent-driven sampling (RDS) is widely used to study hidden or hard-to-reach populations by incentivizing study participants to recruit their social connections. The success and efficiency of RDS can depend critically on the nature of…

Methodology · Statistics 2025-01-06 Justin Weltz , Angela Yoon , Yichi Zhang , Alexander Volfovsky , Eric Laber

In this work, we introduce a method to fine-tune a Transformer-based generative model for molecular de novo design. Leveraging the superior sequence learning capacity of Transformers over Recurrent Neural Networks (RNNs), our model can…

Machine Learning · Computer Science 2024-03-11 Pengcheng Xu , Tao Feng , Tianfan Fu , Siddhartha Laghuvarapu , Jimeng Sun

Safe Reinforcement Learning (SRL) aims to realize a safe learning process for Deep Reinforcement Learning (DRL) algorithms by incorporating safety constraints. However, the efficacy of SRL approaches often relies on accurate function…

Artificial Intelligence · Computer Science 2025-01-15 Zhehua Zhou , Xuan Xie , Jiayang Song , Zhan Shu , Lei Ma

Constrained synthesizability is an unaddressed challenge in generative molecular design. In particular, designing molecules satisfying multi-parameter optimization objectives, while simultaneously being synthesizable and enforcing the…

Biomolecules · Quantitative Biology 2024-10-16 Jeff Guo , Philippe Schwaller

Finding meaningful and accurate dense rewards is a fundamental task in the field of reinforcement learning (RL) that enables agents to explore environments more efficiently. In traditional RL settings, agents learn optimal policies through…

Artificial Intelligence · Computer Science 2025-12-05 Shuyuan Zhang

Generative machine learning models for exploring chemical space have shown immense promise, but many molecules they generate are too difficult to synthesize, making them impractical for further investigation or development. In this work, we…

Aiming to produce reinforcement learning (RL) policies that are human-interpretable and can generalize better to novel scenarios, Trivedi et al. (2021) present a method (LEAPS) that first learns a program embedding space to continuously…

Machine Learning · Computer Science 2023-06-01 Guan-Ting Liu , En-Pei Hu , Pu-Jen Cheng , Hung-yi Lee , Shao-Hua Sun

Modern cyber-physical systems are becoming increasingly complex to model, thus motivating data-driven techniques such as reinforcement learning (RL) to find appropriate control agents. However, most systems are subject to hard constraints…

This paper presents a review of the field of reinforcement learning (RL), with a focus on providing a comprehensive overview of the key concepts, techniques, and algorithms for beginners. RL has a unique setting, jargon, and mathematics…

Machine Learning · Computer Science 2023-04-04 Mohamed-Amine Chadi , Hajar Mousannif

Logic synthesis, a pivotal stage in chip design, entails optimizing chip specifications encoded in hardware description languages like Verilog into highly efficient implementations using Boolean logic gates. The process involves a…

Machine Learning · Computer Science 2024-01-23 Animesh Basak Chowdhury , Marco Romanelli , Benjamin Tan , Ramesh Karri , Siddharth Garg

Conducting reinforcement learning (RL) in simulated environments offers a cost-effective and highly scalable way to enhance language-based agents. However, previous work has been limited to semi-automated environment synthesis or tasks…

Computation and Language · Computer Science 2025-12-30 Shihao Cai , Runnan Fang , Jialong Wu , Baixuan Li , Xinyu Wang , Yong Jiang , Liangcai Su , Liwen Zhang , Wenbiao Yin , Zhen Zhang , Fuli Feng , Pengjun Xie , Xiaobin Wang

Despite achieving superior performance in human-level control problems, unlike humans, deep reinforcement learning (DRL) lacks high-order intelligence (e.g., logic deduction and reuse), thus it behaves ineffectively than humans regarding…

Artificial Intelligence · Computer Science 2022-05-30 Yushi Cao , Zhiming Li , Tianpei Yang , Hao Zhang , Yan Zheng , Yi Li , Jianye Hao , Yang Liu

Discovering novel stable molecules without training data remains a grand scientific challenge. Current molecular generative models are trained on large, pre-curated datasets, which introduce biases and limit exploration of novel chemistry.…

Machine Learning · Computer Science 2026-05-28 Bjarke Hastrup , Francois Cornet , Tejs Vegge , Arghya Bhowmik

A key challenge for reinforcement learning is solving long-horizon planning problems. Recent work has leveraged programs to guide reinforcement learning in these settings. However, these approaches impose a high manual burden on the user…

Artificial Intelligence · Computer Science 2021-11-03 Yichen David Yang , Jeevana Priya Inala , Osbert Bastani , Yewen Pu , Armando Solar-Lezama , Martin Rinard

Foundation models contain a wealth of information from their vast number of training samples. However, most prior arts fail to extract this information in a precise and efficient way for small sample sizes. In this work, we propose a…

Machine Learning · Computer Science 2024-04-26 Nico Schiavone , Xingyu Li

Data preparation is a foundational yet notoriously challenging component of the machine learning lifecycle, characterized by a vast combinatorial search space. While reinforcement learning (RL) offers a promising direction, state-of-the-art…

Databases · Computer Science 2025-07-29 Jing Chang , Chang Liu , Jinbin Huang , Shuyuan Zheng , Rui Mao , Jianbin Qin

We propose a compositional approach to synthesize policies for networks of continuous-space stochastic control systems with unknown dynamics using model-free reinforcement learning (RL). The approach is based on implicitly abstracting each…

Systems and Control · Electrical Eng. & Systems 2022-08-09 Abolfazl Lavaei , Mateo Perez , Milad Kazemi , Fabio Somenzi , Sadegh Soudjani , Ashutosh Trivedi , Majid Zamani
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