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In Proteomics, only the de novo peptide sequencing approach allows a partial amino acid sequence of a peptide to be found from a MS/MS spectrum. In this article a preliminary work is presented to discover a complete protein sequence from…

Quantitative Methods · Quantitative Biology 2008-12-18 Jean-Charles Boisson , Laetitia Jourdan , El-Ghazali Talbi , Christian Rolando

Algorithms that detect covariance between pairs of columns in multiple sequence alignments are commonly employed to predict functionally important residues and structural contacts. However, the assumption that co-variance only occurs…

Quantitative Methods · Quantitative Biology 2014-01-07 Kyle E. Kreth , Anthony A. Fodor

Electron spin resonance (ESR) pulsed dipolar spectroscopy (PDS) is used in protein 3D structure determination. However, the accuracy of the signal analysis depends heavily on the background correction process. In this work, we derive the…

Quantitative Methods · Quantitative Biology 2021-07-01 Aritro Sinha Roy

We show that measurements of semi-inclusive $\pi^\pm$ asymmetries on $p$ and $n$ with polarized and unpolarized target and beams allow, without any knowledge of the polarized parton densities 1) to test independent fragmentation and SU(2)…

High Energy Physics - Phenomenology · Physics 2016-09-06 Ekaterina Christova , Elliot Leader

While electron microscopy offers crucial atomic-resolution insights into structure-property relationships, radiation damage severely limits its use on beam-sensitive materials like proteins and 2D materials. To overcome this challenge, we…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Zifei Wang , Zian Mao , Xiaoya He , Xi Huang , Haoran Zhang , Chun Cheng , Shufen Chu , Tingzheng Hou , Xiaoqin Zeng , Yujun Xie

Despite the significant increase in computational power, molecular modeling of protein structure using classical all-atom approaches remains inefficient, at least for most of the protein targets in the focus of biomedical research. Perhaps…

Biomolecules · Quantitative Biology 2016-11-01 Sebastian Kmiecik , Andrzej Kolinski

The method of Probability Density Profile Analysis has been introduced previously as a tool to find the best match between a set of experimentally generated Residual Dipolar Couplings and a set of known protein structures. While it proved…

Biomolecules · Quantitative Biology 2019-11-07 Ryan Yandle , Rishi Mukhopadhyay , Homayoun Valafar

This paper introduces an efficient algorithm based on the Parity-Consistent Decomposition (PCD) method to determine the WD of pre-transformed polar codes. First, to address the bit dependencies introduced by the pre-transformation matrix,…

Information Theory · Computer Science 2026-01-13 Yang Liu , Bolin Wu , Yuxin Han , Kai Niu

The piecewise constant Mumford-Shah (PCMS) model and the Rudin-Osher-Fatemi (ROF) model are two important variational models in image segmentation and image restoration, respectively. In this paper, we explore a linkage between these…

Numerical Analysis · Mathematics 2020-05-14 Xiaohao Cai , Raymond Chan , Carola-Bibiane Schonlieb , Gabriele Steidl , Tieyong Zeng

Objective: To assess automatic computer-aided in-situ recognition of morphological features of pure and mixed urinary stones using intraoperative digital endoscopic images acquired in a clinical setting. Materials and methods: In this…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Vincent Estrade , Michel Daudon , Emmanuel Richard , Jean-Christophe Bernhard , Franck Bladou , Gregoire Robert , Baudouin Denis de Senneville

Transforming bi-dimensional sets of image pixels into mono-dimensional sequences with a Peano scan (PS) is an established technique enabling the use of hidden Markov chains (HMCs) for unsupervised image segmentation. Related Bayesian…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Clément Fernandes , Wojciech Pieczynski

We propose differential phase contrast (DPC) imaging using energy-filtered electrons to image the magnetic properties of materials at the atomic scale. Compared to DPC measurements with elastic electrons, our simulations predict about two…

Materials Science · Physics 2024-09-02 Devendra Singh Negi , Peter A. van Aken , Jan Rusz

Due to low tissue contrast, irregular object appearance, and unpredictable location variation, segmenting the objects from different medical imaging modalities (e.g., CT, MR) is considered as an important yet challenging task. In this…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Jinquan Sun , Yinghuan Shi , Yang Gao , Lei Wang , Luping Zhou , Wanqi Yang , Dinggang Shen

Photon-Counting Computed Tomography (PCCT) is a novel imaging modality that simultaneously acquires volumetric data at multiple X-ray energy levels, generating separate volumes that capture energy-dependent attenuation properties.…

Human-Computer Interaction · Computer Science 2025-08-21 Mohit Sharma , Emma Nilsson , Martin Falk , Talha Bin Masood , Lee Jollans , Anders Persson , Tino Ebbers , Ingrid Hotz

Medical imaging based prostate cancer diagnosis procedure uses intra-operative transrectal ultrasound (TRUS) imaging to visualize the prostate shape and location to collect tissue samples. Correct tissue sampling from prostate requires…

Computer Vision and Pattern Recognition · Computer Science 2019-03-22 M. S. Hossain , A. P. Paplinski , J. M. Betts

The feasibility of low-energy fragmentation experiments using a magnetic spectrometer is discussed. The main challenge is the multiplicity of the ionic charge states, which can hamper the identification in both Z and A of the fragments.…

Nuclear Experiment · Physics 2009-11-10 L. Audouin , L. Tassan-Got , P. Armbruster , K. -H. Schmidt , C. Stephan , J. Taieb

The contributions of this thesis stem from technology developed to analyse large sets of volumetric images in terms of atom-like features extracted in 3D image space, following SIFT algorithm in 2D image space. New feature properties are…

Image and Video Processing · Electrical Eng. & Systems 2022-08-29 Laurent Chauvin

Deep neural networks have achieved satisfactory performance in piles of medical image analysis tasks. However the training of deep neural network requires a large amount of samples with high-quality annotations. In medical image…

Computer Vision and Pattern Recognition · Computer Science 2020-07-08 Jixin Wang , Sanping Zhou , Chaowei Fang , Le Wang , Jinjun Wang

The Pixel-Imaging Mass Spectrometry (PImMS) camera allows for 3D charged particle imaging measurements, in which the particle time-of-flight is recorded along with $(x,y)$ position. Coupling the PImMS camera to an ultrafast pump-probe…

Many-body physics of electron-electron correlations plays a central role in condensed mater physics, it governs a wide range of phenomena, stretching from superconductivity to magnetism, and is behind numerous technological applications. To…

Mesoscale and Nanoscale Physics · Physics 2023-06-09 Anupam Bhattacharya , Ivan Timokhin , Ratnamala Chatterjee , Qian Yang , Artem Mishchenko
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