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Variable selection in high-dimensional space characterizes many contemporary problems in scientific discovery and decision making. Many frequently-used techniques are based on independence screening; examples include correlation ranking…

Methodology · Statistics 2008-12-18 Jianqing Fan , Richard Samworth , Yichao Wu

The modeling and simulation of high-dimensional multiscale systems is a critical challenge across all areas of science and engineering. It is broadly believed that even with today's computer advances resolving all spatiotemporal scales…

Machine Learning · Statistics 2023-09-13 Emmanuel Menier , Sebastian Kaltenbach , Mouadh Yagoubi , Marc Schoenauer , Petros Koumoutsakos

Multimodal deep learning methods capture synergistic features from multiple modalities and have the potential to improve accuracy for stress detection compared to unimodal methods. However, this accuracy gain typically comes from high…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Morteza Bodaghi , Majid Hosseini , Raju Gottumukkala

We present ImmuVis, a family of efficient foundation models for imaging mass cytometry (IMC), a high-throughput multiplex imaging technology that handles molecular marker measurements as image channels and enables large-scale spatial tissue…

This paper addresses the problem of mapping high-dimensional data to a low-dimensional space, in the presence of other known features. This problem is ubiquitous in science and engineering as there are often controllable/measurable features…

Machine Learning · Statistics 2024-01-01 Anh Tuan Bui

We present DeepMVI, a deep learning method for missing value imputation in multidimensional time-series datasets. Missing values are commonplace in decision support platforms that aggregate data over long time stretches from disparate…

Machine Learning · Computer Science 2023-06-22 Parikshit Bansal , Prathamesh Deshpande , Sunita Sarawagi

In high-dimensional prediction problems, where the number of features may greatly exceed the number of training instances, fully Bayesian approach with a sparsifying prior is known to produce good results but is computationally challenging.…

Methodology · Statistics 2018-10-15 Juho Piironen , Aki Vehtari

Technological advances have enabled the generation of unique and complementary types of data or views (e.g. genomics, proteomics, metabolomics) and opened up a new era in multiview learning research with the potential to lead to new…

Machine Learning · Computer Science 2024-02-19 Hengkang Wang , Han Lu , Ju Sun , Sandra E Safo

Efficiently estimating system dynamics from data is essential for minimizing data collection costs and improving model performance. This work addresses the challenge of designing future control inputs to maximize information gain, thereby…

Systems and Control · Electrical Eng. & Systems 2025-04-29 Joshua Ott , Mykel J. Kochenderfer , Stephen Boyd

Coarse-grained modeling and efficient computer simulations are critical to the study of complex molecular processes with many degrees of freedom and multiple spatiotemporal scales. Variational implicit-solvent model (VISM) for biomolecular…

Chemical Physics · Physics 2022-10-26 Shuang Liu , Zirui Zhang , Li-Tien Cheng , Bo Li

Deep Learning (DL) algorithms hold great promise for applications in the field of computational biophysics. In fact, the vast amount of available molecular structures, as well as their notable complexity, constitutes an ideal context in…

Soft Condensed Matter · Physics 2019-01-07 Marco Giulini , Raffaello Potestio

Video instance segmentation (VIS) is a critical task with diverse applications, including autonomous driving and video editing. Existing methods often underperform on complex and long videos in real world, primarily due to two factors.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Tao Zhang , Xingye Tian , Yu Wu , Shunping Ji , Xuebo Wang , Yuan Zhang , Pengfei Wan

Analyzing large volumes of high-dimensional data requires dimensionality reduction: finding meaningful low-dimensional structures hidden in their high-dimensional observations. Such practice is needed in atomistic simulations of complex…

Computational Physics · Physics 2023-10-17 Jakub Rydzewski , Ming Chen , Omar Valsson

Dynamic substructuring (DS) methods encompass a range of techniques to decompose large structural systems into multiple coupled subsystems. This decomposition has the principle benefit of reducing computational time for dynamic simulation…

Computational Engineering, Finance, and Science · Computer Science 2020-07-01 Thomas Simpson , Dimitrios Giagopoulos , Vasilis Dertimanis , Eleni Chatzi

Virtual screening (VS) is an essential technique for understanding biomolecular interactions, particularly, drug design and discovery. The best-performing VS models depend vitally on three-dimensional (3D) structures, which are not…

Biomolecules · Quantitative Biology 2022-12-29 Li Shen , Hongsong Feng , Yuchi Qiu , Guo-Wei Wei

A variable screening procedure via correlation learning was proposed Fan and Lv (2008) to reduce dimensionality in sparse ultra-high dimensional models. Even when the true model is linear, the marginal regression can be highly nonlinear. To…

Methodology · Statistics 2011-01-19 Jianqing Fan , Yang Feng , Rui Song

Multidimensional scaling (MDS) is a popular dimensionality reduction techniques that has been widely used for network visualization and cooperative localization. However, the traditional stress minimization formulation of MDS necessitates…

Optimization and Control · Mathematics 2016-12-22 Ketan Rajawat , Sandeep Kumar

Instruction following is crucial in contemporary LLM. However, when extended to multimodal setting, it often suffers from misalignment between specific textual instruction and targeted local region of an image. To achieve more accurate and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Jinliang Zheng , Jianxiong Li , Sijie Cheng , Yinan Zheng , Jiaming Li , Jihao Liu , Yu Liu , Jingjing Liu , Xianyuan Zhan

Conventional deep learning models deal with images one-by-one, requiring costly and time-consuming expert labeling in the field of medical imaging, and domain-specific restriction limits model generalizability. Visual in-context learning…

Unsupervised learning makes manifest the underlying structure of data without curated training and specific problem definitions. However, the inference of relationships between data points is frustrated by the `curse of dimensionality' in…