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Optical coherence tomography angiography (OCTA) can non-invasively image the eye's circulatory system. In order to reliably characterize the retinal vasculature, there is a need to automatically extract quantitative metrics from these…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Martin J. Menten , Johannes C. Paetzold , Alina Dima , Bjoern H. Menze , Benjamin Knier , Daniel Rueckert

To establish the tissue regions necessary to accurately represent the mechanics of the optic nerve head (ONH), imaging data of the ONH from 2 healthy subjects were used to create in vivo subject-specific eye mechanical models considering…

Medical Physics · Physics 2025-05-01 Soumaya Ouhsousou , Lucy Q. Shen , Chhavi Saini , Amin Pourasghar , Mengyu Wang , John C. Brigham

Due to its noninvasive character, optical coherence tomography (OCT) has become a popular diagnostic method in clinical settings. However, the low-coherence interferometric imaging procedure is inevitably contaminated by heavy speckle…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Yongqiang Huang , Wenjun Xia , Zexin Lu , Yan Liu , Hu Chen , Jiliu Zhou , Leyuan Fang , Yi Zhang

In order to realize fast OCT-systems with adjustable line rate, we investigate averaging of image data from an FDML based MHz-OCT-system. The line rate can be reduced in software and traded in for increased system sensitivity and image…

Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. Due to the underlying physics, OCT images usually suffer from a granular…

Computer Vision and Pattern Recognition · Computer Science 2015-02-10 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

How the brain co-ordinates the actions of distant regions in an efficient manner is an open problem. Many believe that cross-frequency coupling between the amplitude of high frequency local field potential oscillations in one region and the…

Neurons and Cognition · Quantitative Biology 2016-04-04 Thomas E. Gorochowski , Rafal Bogacz , Matthew Jones

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

A recent advance in optical coherence tomography (OCT), termed swept-source OCT, is generalized into a new technique, Fourier-domain OCT. It represents a realization of a full-field OCT system in place of the conventional serial image…

Optical coherence tomography (OCT) is an established imaging technology for in vivo skin investigation. Topical application of gold nanoshells (GNS) provides contrast enhancement in OCT by generating a strong hyperreflective signal from…

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie

Optical Coherence Tomography (OCT) is an emerging medical imaging modality for luminal organ diagnosis. The non-constant rotation speed of optical components in the OCT catheter tip causes rotational distortion in OCT volumetric scanning.…

Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Dewei Hu , Yuankai K. Tao , Ipek Oguz

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…

Reducing the bit-depth is an effective approach to lower the cost of optical coherence tomography (OCT) systems and increase the transmission efficiency in data acquisition and telemedicine. However, a low bit-depth will lead to the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-03 Qiangjiang Hao , Kang Zhou , Jianlong Yang , Liyang Fang , Zhengjie Chai , Yuhui Ma , Yan Hu , Shenghua Gao , Jiang Liu

Non-invasive observation of spatiotemporal neural activity of large neural populations distributed over entire brains is a longstanding goal of neuroscience. We developed a real-time volumetric and multispectral optoacoustic tomography…

Neurons and Cognition · Quantitative Biology 2015-01-13 Gali Sela , Antonella Lauri , X. Luís Deán-Ben , Moritz Kneipp , Vasilis Ntziachristos , Shy Shoham , Gil G. Westmeyer , Daniel Razansky

Inpainting shadowed regions cast by superficial blood vessels in retinal optical coherence tomography (OCT) images is critical for accurate and robust machine analysis and clinical diagnosis. Traditional sequence-based approaches such as…

Computer Vision and Pattern Recognition · Computer Science 2022-02-24 Yaoqi Tang , Yufan Li , Hongshan Liu , Jiaxuan Li , Peiyao Jin , Yu Gan , Yuye Ling , Yikai Su

Forward-viewing endoscopic optical coherence tomography (OCT) provides 3D imaging in vivo, and can be combined with widefield fluorescence imaging by use of a double-clad fiber. However, it is technically challenging to build a…

The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here…

Purpose: Reliability for Nerve Fiber Layer Reflectance Using Spectral Domain Optical Coherence Tomography (OCT) Methods: The study utilized OCT to scan participants with a cubic 6x6 mm disc scan. NFL reflectance were normalized by the…

Quantitative Methods · Quantitative Biology 2024-06-04 Kabir Hossain , Ou Tan , Po-Han Yeh , Jie Wang , Elizabeth White , Dongseok Choi , David Huang
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