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Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

We present HyperMorph, a learning-based strategy for deformable image registration that removes the need to tune important registration hyperparameters during training. Classical registration methods solve an optimization problem to find a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Andrew Hoopes , Malte Hoffmann , Bruce Fischl , John Guttag , Adrian V. Dalca

We present a deep learning strategy that enables, for the first time, contrast-agnostic semantic segmentation of completely unpreprocessed brain MRI scans, without requiring additional training or fine-tuning for new modalities. Classical…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Benjamin Billot , Douglas Greve , Koen Van Leemput , Bruce Fischl , Juan Eugenio Iglesias , Adrian V. Dalca

Multi-contrast image registration is a challenging task due to the complex intensity relationships between different imaging contrasts. Conventional image registration methods are typically based on iterative optimizations for each input…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Yinsong Wang , Siyi Du , Shaoming Zheng , Xinzhe Luo , Chen Qin

Nonlinear inter-modality registration is often challenging due to the lack of objective functions that are good proxies for alignment. Here we propose a synthesis-by-registration method to convert this problem into an easier intra-modality…

Computer Vision and Pattern Recognition · Computer Science 2023-01-30 Adrià Casamitjana , Matteo Mancini , Juan Eugenio Iglesias

Purpose A Magnetic Resonance Imaging (MRI) exam typically consists of several sequences that yield different image contrasts. Each sequence is parameterized through multiple acquisition parameters that influence image contrast,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jonas Denck , Jens Guehring , Andreas Maier , Eva Rothgang

Multi-contrast MRI acquisitions of an anatomy enrich the magnitude of information available for diagnosis. Yet, excessive scan times associated with additional contrasts may be a limiting factor. Two mainstream approaches for enhanced scan…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Salman Ul Hassan Dar , Mahmut Yurt , Mohammad Shahdloo , Muhammed Emrullah Ildız , Tolga Çukur

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung

A novel non-rigid image registration algorithm is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered in a self-supervised learning framework. Different from…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Hongming Li , Yong Fan

In this study, we develop a physics-informed deep learning-based method to synthesize multiple brain magnetic resonance imaging (MRI) contrasts from a single five-minute acquisition and investigate its ability to generalize to arbitrary…

The adversarial methods showed advanced performance by producing synthetic images to mitigate the domain shift, a common problem due to the hardship of acquiring labelled data in medical field. Most existing studies focus on modifying the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Xinwen Zhang , Chaoyi Zhang , Dongnan Liu , Qianbi Yu , Weidong Cai

Recent advances in deep learning-based medical image registration have shown that training deep neural networks~(DNNs) does not necessarily require medical images. Previous work showed that DNNs trained on randomly generated images with…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Junyu Chen , Shuwen Wei , Yihao Liu , Aaron Carass , Yong Du

Deep learning approaches to the segmentation of magnetic resonance images have shown significant promise in automating the quantitative analysis of brain images. However, a continuing challenge has been its sensitivity to the variability of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dzung L. Pham , Yi-Yu Chou , Blake E. Dewey , Daniel S. Reich , John A. Butman , Snehashis Roy

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated modalities -- notably magnetic resonance (MR) imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Peirong Liu , Oula Puonti , Xiaoling Hu , Daniel C. Alexander , Juan E. Iglesias

A Magnetic Resonance Imaging (MRI) exam typically consists of the acquisition of multiple MR pulse sequences, which are required for a reliable diagnosis. Each sequence can be parameterized through multiple acquisition parameters affecting…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jonas Denck , Jens Guehring , Andreas Maier , Eva Rothgang

Learning-based synthetic multi-contrast MRI commonly involves deep models trained using high-quality images of source and target contrasts, regardless of whether source and target domain samples are paired or unpaired. This results in…

Image and Video Processing · Electrical Eng. & Systems 2021-05-13 Mahmut Yurt , Salman Ul Hassan Dar , Muzaffer Özbey , Berk Tınaz , Kader Karlı Oğuz , Tolga Çukur

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Current contrastive learning methods use random transformations sampled from a large list of transformations, with fixed hyperparameters, to learn invariance from an unannotated database. Following previous works that introduce a small…

Machine Learning · Computer Science 2023-08-21 Camille Ruppli , Pietro Gori , Roberto Ardon , Isabelle Bloch

Despite advances in data augmentation and transfer learning, convolutional neural networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans, CNNs are highly sensitive to changes in resolution and contrast: even…

Image and Video Processing · Electrical Eng. & Systems 2023-03-01 Benjamin Billot , Douglas N. Greve , Oula Puonti , Axel Thielscher , Koen Van Leemput , Bruce Fischl , Adrian V. Dalca , Juan Eugenio Iglesias
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