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Discriminating patients with Alzheimer's disease (AD) from healthy subjects is a crucial task in the research of Alzheimer's disease. The task can be potentially achieved by linear discriminant analysis (LDA), which is one of the most…

Methodology · Statistics 2020-05-05 Yingjie Li , Liangliang Zhang , Tapabrata Maiti

The objective of this study is to derive functional networks for the autism spectrum disorder (ASD) population using the group ICA and dictionary learning model together and to classify ASD and typically developing (TD) participants using…

Neurons and Cognition · Quantitative Biology 2021-06-17 Xin Yang , Ning Zhang , Donglin Wang

The growing use of neuroimaging technologies generates a massive amount of biomedical data that exhibit high dimensionality. Tensor-based analysis of brain imaging data has been proved quite effective in exploiting their multiway nature.…

Numerical Analysis · Computer Science 2016-07-21 Christos Chatzichristos , Eleftherios Kofidis , Giannis Kopsinis , Sergios Theodoridis

Functional magnetic resonance imaging (fMRI) data contain complex spatiotemporal dynamics, thus researchers have developed approaches that reduce the dimensionality of the signal while extracting relevant and interpretable dynamics. Models…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Eloy Geenjaar , Amrit Kashyap , Noah Lewis , Robyn Miller , Vince Calhoun

Autism spectrum disorder is one of the leading neurodevelopmental disorders in our world, present in over 1% of the population and rapidly increasing in prevalence, yet the condition lacks a robust, objective, and efficient diagnostic.…

Neurons and Cognition · Quantitative Biology 2024-03-04 Annie Adhikary

Schizophrenia is a chronic neuropsychiatric disorder that causes distinct structural alterations within the brain. We hypothesize that deep learning applied to a structural neuroimaging dataset could detect disease-related alteration and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Junhao Zhang , Vishwanatha M. Rao , Ye Tian , Yanting Yang , Nicolas Acosta , Zihan Wan , Pin-Yu Lee , Chloe Zhang , Lawrence S. Kegeles , Scott A. Small , Jia Guo

Autism Spectrum Disorder (ASD) presents significant challenges in early diagnosis and intervention, impacting children and their families. With prevalence rates rising, there is a critical need for accessible and efficient screening tools.…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Halil Ismail Helvaci , Sen-ching Samson Cheung , Chen-Nee Chuah , Sally Ozonoff

Early diagnosis of Alzheimer Diagnostics (AD) is a challenging task due to its subtle and complex clinical symptoms. Deep learning-assisted medical diagnosis using image recognition techniques has become an important research topic in this…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Yihao Lin , Ximeng Li , Yan Zhang , Jinshan Tang

Discovering reliable measures that inform on autism spectrum disorder (ASD) diagnosis is critical for providing appropriate and timely treatment for this neurodevelopmental disorder. In this work we present applications of adversarial…

Machine Learning · Computer Science 2021-12-01 William E. Carson , Dmitry Isaev , Samatha Major , Guillermo Sapiro , Geraldine Dawson , David Carlson

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…

Machine Learning · Computer Science 2024-11-21 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

This paper applies a hidden Markov model to the problem of Attention Deficit Hyperactivity Disorder (ADHD) diagnosis from resting-state functional Magnetic Resonance Image (fMRI) scans of subjects. The proposed model considers the temporal…

Quantitative Methods · Quantitative Biology 2015-06-22 Bhaskar Sen , Zheng Shi , Gregory Burlet

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Autism spectrum disorder (ASD) is a prevalent psychiatric condition characterized by atypical cognitive, emotional, and social patterns. Timely and accurate diagnosis is crucial for effective interventions and improved outcomes in…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Lucas Mahler , Qi Wang , Julius Steiglechner , Florian Birk , Samuel Heczko , Klaus Scheffler , Gabriele Lohmann

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Conventionally, evaluation for the diagnosis of Autism spectrum disorder is done by a trained specialist through questionnaire-based formal assessments and by observation of behavioral cues under various settings to capture the early…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Vaibhavi Lokegaonkar , Vijay Jaisankar , Pon Deepika , Madhav Rao , T K Srikanth , Sarbani Mallick , Manjit Sodhi

Autism and Attention-Deficit Hyperactivity Disorder (ADHD) are two of the most commonly observed neurodevelopmental conditions in childhood. Providing a specific computational assessment to distinguish between the two can prove difficult…

Machine Learning · Computer Science 2024-11-19 Aditi Jaiswal , Dennis P. Wall , Peter Washington

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

The early diagnosis of autism spectrum disorder (ASD) is critically dependent on systematic observation and analysis of children's social behaviors. While current methodologies predominantly utilize supervised learning approaches, their…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Wenxing Liu , Yueran Pan , Dong Zhang , Hongzhu Deng , Xiaobing Zou , Ming Li

Accurate and efficient classification of Alzheimer's disease (AD) severity from brain magnetic resonance imaging (MRI) remains a critical challenge, particularly when limited data and model interpretability are of concern. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Faisal Ahmed

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang