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Vision-Language Models (VLMs) such as CLIP have yielded unprecedented performance for zero-shot image classification, yet their generalization capability may still be seriously challenged when confronted to domain shifts. In response, we…

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Whole-slide images (WSI) in computational pathology have high resolution with gigapixel size, but are generally with sparse regions of interest, which leads to weak diagnostic relevance and data inefficiency for each area in the slide. Most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Boxuan Zhao , Jun Zhang , Deheng Ye , Jian Cao , Xiao Han , Qiang Fu , Wei Yang

Whole Slide Images (WSIs) are high-resolution digital scans widely used in medical diagnostics. WSI classification is typically approached using Multiple Instance Learning (MIL), where the slide is partitioned into tiles treated as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Moving objects can greatly jeopardize the performance of a visual simultaneous localization and mapping (vSLAM) system which relies on the static-world assumption. Motion removal have seen successful on solving this problem. Two main…

Robotics · Computer Science 2019-08-01 Ting Sun , Yuxiang Sun , Ming Liu , Dit-Yan Yeung

We propose a novel scalable end-to-end pipeline that uses symbolic domain knowledge as constraints for learning a neural network for classifying unlabeled data in a weak-supervised manner. Our approach is particularly well-suited for…

Machine Learning · Computer Science 2023-10-23 Sudhir Agarwal , Anu Sreepathy , Lalla Mouatadid

AI-enabled precision medicine promises a transformational improvement in healthcare outcomes by enabling data-driven personalized diagnosis, prognosis, and treatment. However, the well-known "curse of dimensionality" and the clustered…

Machine Learning · Computer Science 2023-05-19 Amanda M. Buch , Conor Liston , Logan Grosenick

In this paper, we consider the problem of planar graph-based simultaneous localization and mapping (SLAM) that involves both poses of the autonomous agent and positions of observed landmarks. We present CPL-SLAM, an efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Taosha Fan , Hanlin Wang , Michael Rubenstein , Todd Murphey

With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Chen Li , Xintong Li , Md Rahaman , Xiaoyan Li , Hongzan Sun , Hong Zhang , Yong Zhang , Xiaoqi Li , Jian Wu , Yudong Yao , Marcin Grzegorzek

Domain adaptation of visual detectors is a critical challenge, yet existing methods have overlooked pixel appearance transformations, focusing instead on bootstrapping and/or domain confusion losses. We propose a Semantic Pixel-Level…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Eric Tzeng , Kaylee Burns , Kate Saenko , Trevor Darrell

Large-scale volumetric medical images with annotation are rare, costly, and time prohibitive to acquire. Self-supervised learning (SSL) offers a promising pre-training and feature extraction solution for many downstream tasks, as it only…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Ke Yu , Li Sun , Junxiang Chen , Max Reynolds , Tigmanshu Chaudhary , Kayhan Batmanghelich

Long-context understanding is crucial for many NLP applications, yet transformers struggle with efficiency due to the quadratic complexity of self-attention. Sparse attention methods alleviate this cost but often impose static, predefined…

Computation and Language · Computer Science 2025-06-16 Hanzhi Zhang , Heng Fan , Kewei Sha , Yan Huang , Yunhe Feng

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Yuci Liang , Xinheng Lyu , Wenting Chen , Meidan Ding , Jipeng Zhang , Xiangjian He , Song Wu , Xiaohan Xing , Sen Yang , Xiyue Wang , Linlin Shen

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Histopathological whole slide image (WSI) analysis with deep learning has become a research focus in computational pathology. The current paradigm is mainly based on multiple instance learning (MIL), in which approaches with Transformer as…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hongbo Chu , Qiehe Sun , Jiawen Li , Yuxuan Chen , Lizhong Zhang , Tian Guan , Anjia Han , Yonghong He

Malicious image manipulation threatens public safety and requires efficient localization methods. Existing approaches depend on costly pixel-level annotations which make training expensive. Existing weakly supervised methods rely only on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Xinghao Wang , Changtao Miao , Dianmo Sheng , Tao Gong , Qi Chu , Nenghai Yu , Quanchen Zou , Deyue Zhang , Xiangzheng Zhang

The recent development of deep learning large models in medicine shows remarkable performance in medical image analysis and diagnosis, but their large number of parameters causes memory and inference latency challenges. Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Shaojie Li , Zhaoshuo Diao

Domain-specific image collections present potential value in various areas of science and business but are often not curated nor have any way to readily extract relevant content. To employ contemporary supervised image analysis methods on…

Machine Learning · Computer Science 2020-03-10 Sara Mousavi , Dylan Lee , Tatianna Griffin , Dawnie Steadman , Audris Mockus

Semi-supervised learning has substantially advanced medical image segmentation since it alleviates the heavy burden of acquiring the costly expert-examined annotations. Especially, the consistency-based approaches have attracted more…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Zhe Xu , Yixin Wang , Donghuan Lu , Lequan Yu , Jiangpeng Yan , Jie Luo , Kai Ma , Yefeng Zheng , Raymond Kai-yu Tong
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