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Accurate segmentation of Multiple Sclerosis (MS) lesions in longitudinal MRI scans is crucial for monitoring disease progression and treatment efficacy. Although changes across time are taken into account when assessing images in clinical…

We propose a dual pathway, 11-layers deep, three-dimensional Convolutional Neural Network for the challenging task of brain lesion segmentation. The devised architecture is the result of an in-depth analysis of the limitations of current…

Computer Vision and Pattern Recognition · Computer Science 2017-01-10 Konstantinos Kamnitsas , Christian Ledig , Virginia F. J. Newcombe , Joanna P. Simpson , Andrew D. Kane , David K. Menon , Daniel Rueckert , Ben Glocker

Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Chinmay Prabhakar , Hongwei Bran Li , Johannes C. Paetzold , Timo Loehr , Chen Niu , Mark Mühlau , Daniel Rueckert , Benedikt Wiestler , Bjoern Menze

Automated brain lesions detection is an important and very challenging clinical diagnostic task because the lesions have different sizes, shapes, contrasts, and locations. Deep Learning recently has shown promising progress in many…

Computer Vision and Pattern Recognition · Computer Science 2018-01-08 Mina Rezaei , Haojin Yang , Christoph Meinel

In this study, a multi-task deep neural network is proposed for skin lesion analysis. The proposed multi-task learning model solves different tasks (e.g., lesion segmentation and two independent binary lesion classifications) at the same…

Computer Vision and Pattern Recognition · Computer Science 2017-03-06 Xulei Yang , Zeng Zeng , Si Yong Yeo , Colin Tan , Hong Liang Tey , Yi Su

In this paper, we propose generating synthetic multiple sclerosis (MS) lesions on MRI images with the final aim to improve the performance of supervised machine learning algorithms, therefore avoiding the problem of the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2019-01-18 Mostafa Salem , Sergi Valverde , Mariano Cabezas , Deborah Pareto , Arnau Oliver , Joaquim Salvi , Àlex Rovira , Xavier Lladó

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

Deep neural networks (DNN) have shown promises in the lesion segmentation of multiple sclerosis (MS) from multicontrast MRI including T1, T2, proton density (PD) and FLAIR sequences. However, one challenge in deploying such networks into…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Yushan Feng , Huitong Pan , Craig Meyer , Xue Feng

Deep learning (DL) networks have recently been shown to outperform other segmentation methods on various public, medical-image challenge datasets [3,11,16], especially for large pathologies. However, in the context of diseases such as…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Tanya Nair , Doina Precup , Douglas L. Arnold , Tal Arbel

The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Francesco La Rosa , Erin S Beck , Ahmed Abdulkadir , Jean-Philippe Thiran , Daniel S Reich , Pascal Sati , Meritxell Bach Cuadra

Sensor-based human activity segmentation and recognition are two important and challenging problems in many real-world applications and they have drawn increasing attention from the deep learning community in recent years. Most of the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Furong Duan , Tao Zhu , Jinqiang Wang , Liming Chen , Huansheng Ning , Yaping Wan

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies

Structural magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients. The formation of these lesions is a complex process involving inflammation, tissue damage, and tissue repair, all…

Acute stroke lesion segmentation tasks are of great clinical interest as they can help doctors make better informed treatment decisions. Magnetic resonance imaging (MRI) is time demanding but can provide images that are considered gold…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Albert Clèrigues , Sergi Valverde , Jose Bernal , Jordi Freixenet , Arnau Oliver , Xavier Lladó

In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

Purpose: Multiple sclerosis (MS) diagnosis requires accurate assessment of white matter hyperintensities (WMH) and ventricular changes on brain MRI. Current methods treat these structures independently, struggle to differentiate normal from…

Image and Video Processing · Electrical Eng. & Systems 2026-02-20 Mahdi Bashiri Bawil , Mousa Shamsi , Abolhassan Shakeri Bavil

The detection of new or enlarged white-matter lesions in multiple sclerosis is a vital task in the monitoring of patients undergoing disease-modifying treatment for multiple sclerosis. However, the definition of 'new or enlarged' is not…

Automated segmentation of multiple sclerosis (MS) lesions from MRI scans is important to quantify disease progression. In recent years, convolutional neural networks (CNNs) have shown top performance for this task when a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jiacheng Wang , Hao Li , Han Liu , Dewei Hu , Daiwei Lu , Keejin Yoon , Kelsey Barter , Francesca Bagnato , Ipek Oguz

Automatic multiple sclerosis (MS) lesion segmentation using multi-contrast magnetic resonance (MR) images provides improved efficiency and reproducibility compared to manual delineation. Current state-of-the-art automatic MS lesion…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Jinwei Zhang , Lianrui Zuo , Blake E. Dewey , Samuel W. Remedios , Dzung L. Pham , Aaron Carass , Jerry L. Prince